parameter values (.csv)

Download original .csv file from GitHub

parameter_name

value

param_label

prior_min

prior_max

prior_note

param_label_note

value_note

Unnamed: 8

old values

0

prev_init_any_by_agegp

[0.070,0.130,0.127,0.024,0.027,0.019]

local

[0.0, 0.0, 0.0, 0.0, 0.0, 0.0]

[1.0, 1.0, 1.0, 1.0, 1.0, 1.0]

vague prior

Malawi-specific

<0.5, [0.5; 1), [1; 2), [2; 3), [3; 4), [4; 5) years, init prevalence of any wasting, ie of WHZ < -2

Ines—prev_init_any_by_agegp = [0.029,0.055,0.032,0.025,0.015,0.023] derived from prev_WHZ_distribution_mean_by_agegp = [0.6562448, 0.055192, 0.0242205, 0.0563448, 0.0934278, -0.0317801], prev_WHZ_distribution_sd_by_agegp = [1.397629, 1.28665, 1.090178, 1.046056, 0.9660208, 0.9833179]

1

prev_init_sev_by_agegp

[0.021,0.071,0.047,0.009,0.007,0.006]

local

[0.0, 0.0, 0.0, 0.0, 0.0, 0.0]

[1.0, 1.0, 1.0, 1.0, 1.0, 1.0]

vague prior

Malawi-specific

<0.5, [0.5; 1), [1; 2), [2; 3), [3; 4), [4; 5) years

Ines—prev_init_sev_by_agegp ~ [0.0044,0.0088,0.0028,0.0017,0.0007,0.0013] derived from prev_WHZ_distribution_mean_by_agegp = [0.6562448, 0.055192, 0.0242205, 0.0563448, 0.0934278, -0.0317801], prev_WHZ_distribution_sd_by_agegp = [1.397629, 1.28665, 1.090178, 1.046056, 0.9660208, 0.9833179]

2

max_age_child_wasting

5

local

1

10

vague prior

3

4

wasting_incidence_polling_freq_months

1

undetermined

1

12

design decision

5

min_days_to_relapse

14

local

0

90

vague prior

guesstimate based on a REF

6

base_overall_inc_rate_wasting

0.0076

undetermined

0

1

calibration

calibrated

0.0019*0.4, reference age group 1-5 months — bathtub model v2 calibrated with duration 81 to 0.019, expected to be lower due to sev→mod wasting not being included and duration likely being smaller on average as recovery and death occurs earlier, proportion calibrated with simulations (wasting_analysis__minimal_model-2025-03-29T233447Z) to 0.4

by agegp: [0.02,0.02,0.02,0.02,0.02,0.02]-Emmanuel assumed; [0.024,0.09,0.15,0.09,0.06, 0.06]–Ines’s rough estimates referred to Maleta etal 2003 Childhood malnutrition and its predictors in rural Malawi; [Maleta et al 2003]– my guesstimates – [0.0023,0.0099,0.0189,0.0102,0.003, 0.002], hence overall base inci rate = 0.0023

7

rr_inc_rate_wasting_by_agegp

[1.00, 1.22, 1.71, 0.30, 0.40, 0.26]

undetermined

[1.00, 0.01, 0.01, 0.01, 0.01, 0.01]

[1.00, 100, 100, 100, 100, 100]

calibration

calibrated

<0.5, [0.5; 1), [1; 2), [2; 3), [3; 4), [4; 5); bathtub model v2 calibrated rr

[Maleta et al 2003] – based on my guesstimates – [0.0023,0.0099,0.0189,0.0102,0.003, 0.002] translated into relative risks [1.00, 4.30, 8.22, 4.43, 1.30, 0.87] to work with the base_overall_inc_rate

8

rr_wasting_AGA_and_preterm

2.11

local

0.01

100

vague prior

sub-Saharan Africa-specific

9

rr_wasting_SGA_and_term

2.26

local

0.01

100

vague prior

sub-Saharan Africa-specific

10

rr_wasting_SGA_and_preterm

3.09

local

0.01

100

vague prior

sub-Saharan Africa-specific

11

rr_wasting_wealth_level

0.5

local

0.01

100

vague prior

slowly increasing, nonlinear relative risk assumed

12

13

min_days_duration_of_wasting

31

local

1

90

lowest bound from the 95% CIs for moderate and severe wasting duration

no REF

14

duration_of_untreated_mod_wasting

81

local

69

93

95% CI

15

duration_of_untreated_sev_wasting

45

local

31

68

95% CI

16

progression_severe_wasting_monthly_by_agegp

[0.3082, 0.8614, 0.4229, 0.4337, 0.2508, 0.3321]

undetermined

[0.0, 0.0, 0.0, 0.0, 0.0, 0.0]

[1.0, 1.0, 1.0, 1.0, 1.0, 1.0]

calibration

calibrated

<0.5, [0.5; 1), [1; 2), [2; 3), [3; 4), [4; 5) years; bathtub model v3 calibrated

[0.0027,0.0036,0.0079,0.0053,0.0025,0.002]– my guesstimates of monthly sev. wast. incidence based on Maleta etal 2003 Childhood malnutrition and its predictors in rural Malawi; [ 0.02,0.02,0.02,0.02,0.02,0.02], [0.5,0.5,0.5,0.5,0.5,0.5] – Emmanuel assumed; [0.02,0.03,0.09,0.05,0.04,0.03]–Ines’s dummy values referred to Maleta etal 2003 Childhood malnutrition and its predictors in rural Malawi

17

prob_complications_in_SAM

0.15

local

0.01

1

vague prior

18

duration_sam_to_death

30

local

1

90

vague prior

guesstimate based on a REF

19

base_death_rate_untreated_SAM

0.03

undetermined

0.00001

0.2

calibration

calibrated

20

rr_death_rate_by_agegp

[1.0, 1.0, 0.8, 0.8, 0.8, 0.8]

local

[1.0, 0.0, 0.0, 0.0, 0.0, 0.0]

[1.0, 1.0, 1.0, 1.0, 1.0, 1.0]

vague prior

no REF

dummy

<0.5, [0.5; 1), [1; 2), [2; 3), [3; 4), [4; 5) years

21

recovery_rate_with_standard_RUTF

0.738

local

0.71

0.774

95% CI

22

recovery_rate_with_soy_RUSF

0.805

local

0.01

0.99

vague prior

Malawi-specific [currently not used]

23

recovery_rate_with_CSB++

0.8

local

0.25

0.95

range in a review study

Malawi-specific

24

recovery_rate_with_inpatient_care

0.704

local

65.4

75.3

95% CI

sub-Saharan Africa-specific

25

tx_length_weeks_SuppFeedingMAM

6

local

4

10

vague prior

Malawi-specific guesstimate based on REFs

26

tx_length_weeks_OutpatientSAM

7

local

2

15

vague prior

guesstimate based on REFs

27

tx_length_weeks_InpatientSAM

8

local

3

20

vague prior

guesstimate based on REFs

28

29

MUAC_distribution_WHZ<-3

[13.81053, 1.467763]

local

[9.5, 0.5]

[16, 2]

vague prior

Malawi-specific [currently not used]

dhs 2015

30

MUAC_distribution_-3<=WHZ<-2

[14.14828, 0.9847482]

local

[11.5, 0.5]

[16, 2]

vague prior

Malawi-specific [currently not used]

31

MUAC_distribution_WHZ>=-2

[15.1793, 1.20386]

local

[12.5, 0.5]

[17, 2]

vague prior

Malawi-specific

Ines referenced MMS 2015

32

33

odds_ratio_health_seeking_wasting_children

20

local

1

100

vague prior

34

growth_monitoring_first

42

local

1

90

vague prior

Malawi-specific

35

growth_monitoring_frequency_days_agecat

[47, 73, 182]

local

[30, 30, 30]

[90, 180, 365]

vague prior

Malawi-specific

<1, [1; 2), [2; 5) years; 7 appts for <1 with the first at 6 weeks of age, 5 appts a year for [1; 2), 2 appts a year for [2; 5) years old

36

growth_monitoring_attendance_prob_agecat

[0.76, 0.14, 0.5]

local

[0.01, 0.01, 0.01]

[1.00, 1.00, 1.00]

vague prior

Malawi-specific, Ghana-specific, Ghana-specific

<1, [1; 2), [2; 5) years

37

38

proportion_WHZ<-3_with_MUAC<115mm

0.4012

local

0.01

0.99

vague prior

(1-0.4012) will be WHZ<-3 with MUAC between 115-125mm

39

proportion_-3<=WHZ<-2_with_MUAC<115mm

0.3358

local

0.01

0.99

vague prior

40

proportion_-3<=WHZ<-2_with_MUAC_[115-125)mm

0.4081

local

0.01

0.99

vague prior

(1-0.3358-0.4081) will be -3<=WHZ<-2 with normal MUAC >125mm

41

proportion_mam_with_MUAC_[115-125)mm_and_normal_whz

0.5367

local

0.01

0.99

vague prior

42

proportion_mam_with_MUAC_[115-125)mm_and_-3<=WHZ<-2

0.2846

local

0.01

0.99

vague prior

43

proportion_mam_with_-3<=WHZ<-2_and_normal_MUAC

0.1787

local

0.01

0.99

vague prior

44

prevalence_nutritional_oedema

0.007

local

0

0.99

vague prior

Malawi-specific

45

proportion_WHZ<-2_with_oedema

0.007228

local

0.01

0.99

vague prior

East Africa-specific

46

proportion_oedema_with_WHZ<-2

0.374709077

local

0

0.99

vague prior

East Africa-specific

0.374709077

47

proportion_normal_whz

0.96

local

0.2

1

vague prior

Malawi-specific

1 - prevalence of wasting in 2010 [DHS 2010]

48

49

prob_death_after_SAMcare

0.011450382

undetermined

0

0.2

calibration

calibrated

0.03*0.1/(1−0.738) prob death after SAM care if not fully recovered (where recovery with tx is 0.1 times the base death rate for untreated SAM)