parameter values (.csv)
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parameter_name |
value |
param_label |
prior_min |
prior_max |
prior_note |
param_label_note |
value_note |
Unnamed: 8 |
old values |
|
|---|---|---|---|---|---|---|---|---|---|---|
0 |
prev_init_any_by_agegp |
[0.070,0.130,0.127,0.024,0.027,0.019] |
local |
[0.0, 0.0, 0.0, 0.0, 0.0, 0.0] |
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0] |
vague prior |
Malawi-specific |
<0.5, [0.5; 1), [1; 2), [2; 3), [3; 4), [4; 5) years, init prevalence of any wasting, ie of WHZ < -2 |
Ines—prev_init_any_by_agegp = [0.029,0.055,0.032,0.025,0.015,0.023] derived from prev_WHZ_distribution_mean_by_agegp = [0.6562448, 0.055192, 0.0242205, 0.0563448, 0.0934278, -0.0317801], prev_WHZ_distribution_sd_by_agegp = [1.397629, 1.28665, 1.090178, 1.046056, 0.9660208, 0.9833179] |
|
1 |
prev_init_sev_by_agegp |
[0.021,0.071,0.047,0.009,0.007,0.006] |
local |
[0.0, 0.0, 0.0, 0.0, 0.0, 0.0] |
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0] |
vague prior |
Malawi-specific |
<0.5, [0.5; 1), [1; 2), [2; 3), [3; 4), [4; 5) years |
Ines—prev_init_sev_by_agegp ~ [0.0044,0.0088,0.0028,0.0017,0.0007,0.0013] derived from prev_WHZ_distribution_mean_by_agegp = [0.6562448, 0.055192, 0.0242205, 0.0563448, 0.0934278, -0.0317801], prev_WHZ_distribution_sd_by_agegp = [1.397629, 1.28665, 1.090178, 1.046056, 0.9660208, 0.9833179] |
|
2 |
max_age_child_wasting |
5 |
local |
1 |
10 |
vague prior |
||||
3 |
||||||||||
4 |
wasting_incidence_polling_freq_months |
1 |
undetermined |
1 |
12 |
design decision |
||||
5 |
min_days_to_relapse |
14 |
local |
0 |
90 |
vague prior |
guesstimate based on a REF |
|||
6 |
base_overall_inc_rate_wasting |
0.0076 |
undetermined |
0 |
1 |
calibration |
calibrated |
0.0019*0.4, reference age group 1-5 months — bathtub model v2 calibrated with duration 81 to 0.019, expected to be lower due to sev→mod wasting not being included and duration likely being smaller on average as recovery and death occurs earlier, proportion calibrated with simulations (wasting_analysis__minimal_model-2025-03-29T233447Z) to 0.4 |
by agegp: [0.02,0.02,0.02,0.02,0.02,0.02]-Emmanuel assumed; [0.024,0.09,0.15,0.09,0.06, 0.06]–Ines’s rough estimates referred to Maleta etal 2003 Childhood malnutrition and its predictors in rural Malawi; [Maleta et al 2003]– my guesstimates – [0.0023,0.0099,0.0189,0.0102,0.003, 0.002], hence overall base inci rate = 0.0023 |
|
7 |
rr_inc_rate_wasting_by_agegp |
[1.00, 1.22, 1.71, 0.30, 0.40, 0.26] |
undetermined |
[1.00, 0.01, 0.01, 0.01, 0.01, 0.01] |
[1.00, 100, 100, 100, 100, 100] |
calibration |
calibrated |
<0.5, [0.5; 1), [1; 2), [2; 3), [3; 4), [4; 5); bathtub model v2 calibrated rr |
[Maleta et al 2003] – based on my guesstimates – [0.0023,0.0099,0.0189,0.0102,0.003, 0.002] translated into relative risks [1.00, 4.30, 8.22, 4.43, 1.30, 0.87] to work with the base_overall_inc_rate |
|
8 |
rr_wasting_AGA_and_preterm |
2.11 |
local |
0.01 |
100 |
vague prior |
sub-Saharan Africa-specific |
|||
9 |
rr_wasting_SGA_and_term |
2.26 |
local |
0.01 |
100 |
vague prior |
sub-Saharan Africa-specific |
|||
10 |
rr_wasting_SGA_and_preterm |
3.09 |
local |
0.01 |
100 |
vague prior |
sub-Saharan Africa-specific |
|||
11 |
rr_wasting_wealth_level |
0.5 |
local |
0.01 |
100 |
vague prior |
slowly increasing, nonlinear relative risk assumed |
|||
12 |
||||||||||
13 |
min_days_duration_of_wasting |
31 |
local |
1 |
90 |
lowest bound from the 95% CIs for moderate and severe wasting duration |
no REF |
|||
14 |
duration_of_untreated_mod_wasting |
81 |
local |
69 |
93 |
95% CI |
||||
15 |
duration_of_untreated_sev_wasting |
45 |
local |
31 |
68 |
95% CI |
||||
16 |
progression_severe_wasting_monthly_by_agegp |
[0.3082, 0.8614, 0.4229, 0.4337, 0.2508, 0.3321] |
undetermined |
[0.0, 0.0, 0.0, 0.0, 0.0, 0.0] |
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0] |
calibration |
calibrated |
<0.5, [0.5; 1), [1; 2), [2; 3), [3; 4), [4; 5) years; bathtub model v3 calibrated |
[0.0027,0.0036,0.0079,0.0053,0.0025,0.002]– my guesstimates of monthly sev. wast. incidence based on Maleta etal 2003 Childhood malnutrition and its predictors in rural Malawi; [ 0.02,0.02,0.02,0.02,0.02,0.02], [0.5,0.5,0.5,0.5,0.5,0.5] – Emmanuel assumed; [0.02,0.03,0.09,0.05,0.04,0.03]–Ines’s dummy values referred to Maleta etal 2003 Childhood malnutrition and its predictors in rural Malawi |
|
17 |
prob_complications_in_SAM |
0.15 |
local |
0.01 |
1 |
vague prior |
||||
18 |
duration_sam_to_death |
30 |
local |
1 |
90 |
vague prior |
guesstimate based on a REF |
|||
19 |
base_death_rate_untreated_SAM |
0.03 |
undetermined |
0.00001 |
0.2 |
calibration |
calibrated |
|||
20 |
rr_death_rate_by_agegp |
[1.0, 1.0, 0.8, 0.8, 0.8, 0.8] |
local |
[1.0, 0.0, 0.0, 0.0, 0.0, 0.0] |
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0] |
vague prior |
no REF |
dummy |
<0.5, [0.5; 1), [1; 2), [2; 3), [3; 4), [4; 5) years |
|
21 |
recovery_rate_with_standard_RUTF |
0.738 |
local |
0.71 |
0.774 |
95% CI |
||||
22 |
recovery_rate_with_soy_RUSF |
0.805 |
local |
0.01 |
0.99 |
vague prior |
Malawi-specific [currently not used] |
|||
23 |
recovery_rate_with_CSB++ |
0.8 |
local |
0.25 |
0.95 |
range in a review study |
Malawi-specific |
|||
24 |
recovery_rate_with_inpatient_care |
0.704 |
local |
65.4 |
75.3 |
95% CI |
sub-Saharan Africa-specific |
|||
25 |
tx_length_weeks_SuppFeedingMAM |
6 |
local |
4 |
10 |
vague prior |
Malawi-specific guesstimate based on REFs |
|||
26 |
tx_length_weeks_OutpatientSAM |
7 |
local |
2 |
15 |
vague prior |
guesstimate based on REFs |
|||
27 |
tx_length_weeks_InpatientSAM |
8 |
local |
3 |
20 |
vague prior |
guesstimate based on REFs |
|||
28 |
||||||||||
29 |
MUAC_distribution_WHZ<-3 |
[13.81053, 1.467763] |
local |
[9.5, 0.5] |
[16, 2] |
vague prior |
Malawi-specific [currently not used] |
dhs 2015 |
||
30 |
MUAC_distribution_-3<=WHZ<-2 |
[14.14828, 0.9847482] |
local |
[11.5, 0.5] |
[16, 2] |
vague prior |
Malawi-specific [currently not used] |
|||
31 |
MUAC_distribution_WHZ>=-2 |
[15.1793, 1.20386] |
local |
[12.5, 0.5] |
[17, 2] |
vague prior |
Malawi-specific |
Ines referenced MMS 2015 |
||
32 |
||||||||||
33 |
odds_ratio_health_seeking_wasting_children |
20 |
local |
1 |
100 |
vague prior |
||||
34 |
growth_monitoring_first |
42 |
local |
1 |
90 |
vague prior |
Malawi-specific |
|||
35 |
growth_monitoring_frequency_days_agecat |
[47, 73, 182] |
local |
[30, 30, 30] |
[90, 180, 365] |
vague prior |
Malawi-specific |
<1, [1; 2), [2; 5) years; 7 appts for <1 with the first at 6 weeks of age, 5 appts a year for [1; 2), 2 appts a year for [2; 5) years old |
||
36 |
growth_monitoring_attendance_prob_agecat |
[0.76, 0.14, 0.5] |
local |
[0.01, 0.01, 0.01] |
[1.00, 1.00, 1.00] |
vague prior |
Malawi-specific, Ghana-specific, Ghana-specific |
<1, [1; 2), [2; 5) years |
||
37 |
||||||||||
38 |
proportion_WHZ<-3_with_MUAC<115mm |
0.4012 |
local |
0.01 |
0.99 |
vague prior |
(1-0.4012) will be WHZ<-3 with MUAC between 115-125mm |
|||
39 |
proportion_-3<=WHZ<-2_with_MUAC<115mm |
0.3358 |
local |
0.01 |
0.99 |
vague prior |
||||
40 |
proportion_-3<=WHZ<-2_with_MUAC_[115-125)mm |
0.4081 |
local |
0.01 |
0.99 |
vague prior |
(1-0.3358-0.4081) will be -3<=WHZ<-2 with normal MUAC >125mm |
|||
41 |
proportion_mam_with_MUAC_[115-125)mm_and_normal_whz |
0.5367 |
local |
0.01 |
0.99 |
vague prior |
||||
42 |
proportion_mam_with_MUAC_[115-125)mm_and_-3<=WHZ<-2 |
0.2846 |
local |
0.01 |
0.99 |
vague prior |
||||
43 |
proportion_mam_with_-3<=WHZ<-2_and_normal_MUAC |
0.1787 |
local |
0.01 |
0.99 |
vague prior |
||||
44 |
prevalence_nutritional_oedema |
0.007 |
local |
0 |
0.99 |
vague prior |
Malawi-specific |
|||
45 |
proportion_WHZ<-2_with_oedema |
0.007228 |
local |
0.01 |
0.99 |
vague prior |
East Africa-specific |
|||
46 |
proportion_oedema_with_WHZ<-2 |
0.374709077 |
local |
0 |
0.99 |
vague prior |
East Africa-specific |
0.374709077 |
||
47 |
proportion_normal_whz |
0.96 |
local |
0.2 |
1 |
vague prior |
Malawi-specific |
1 - prevalence of wasting in 2010 [DHS 2010] |
||
48 |
||||||||||
49 |
prob_death_after_SAMcare |
0.011450382 |
undetermined |
0 |
0.2 |
calibration |
calibrated |
0.03*0.1/(1−0.738) prob death after SAM care if not fully recovered (where recovery with tx is 0.1 times the base death rate for untreated SAM) |