Parameters

Default parameter values used in simulations.

Alri

Name

Description

Type

Value

base_inc_rate_ALRI_by_RSV

baseline incidence rate of Alri caused by RSV in age groups 0-11, 12-23, 24-59 months, per child per year

List

[0.165623001012122, 0.0368943809605977, 0.011883807410198]

base_inc_rate_ALRI_by_Rhinovirus

baseline incidence of Alri caused by Rhinovirus in age groups 0-11, 12-23, 24-59 months, per child per year

List

[0.0243368081563306, 0.0564272209432261, 0.0181754025659935]

base_inc_rate_ALRI_by_HMPV

baseline incidence of Alri caused by HMPV in age groups 0-11, 12-23, 24-59 months, per child per year

List

[0.0316242920447732, 0.01106932885584, 0.00356546901880363]

base_inc_rate_ALRI_by_Parainfluenza

baseline incidence of Alri caused by Parainfluenza 1-4 in age groups 0-11, 12-23, 24-59 months, per child per year

List

[0.0400689053941642, 0.0125990679490263, 0.00405820325903094]

base_inc_rate_ALRI_by_Strep_pneumoniae_PCV13

baseline incidence of Alri caused by Streptoccocus pneumoniae PCV13 serotype in age groups 0-11, 12-23, 24-59 months, per child per year

List

[0.00839805492638728, 0.0086009815601405, 0.00277040583791159]

base_inc_rate_ALRI_by_Strep_pneumoniae_non_PCV13

baseline incidence of Alri caused by Streptoccocus pneumoniae non PCV13 serotype in age groups 0-11, 12-23, 24-59 months, per child per year

List

[0.00971808948465436, 0.0056295094957977, 0.00181328443302487]

base_inc_rate_ALRI_by_Hib

baseline incidence of Alri caused by Haemophilus influenzae type b in age groups 0-11, 12-23, 24-59 months, per child per year

List

[0.00456369209787862, 0.00223809928508262, 0.000720899502209533]

base_inc_rate_ALRI_by_H.influenzae_non_type_b

baseline incidence of Alri caused by Haemophilus influenzae non-type b in age groups 0-11, 12-23, 24-59 months, per child per year

List

[0.0178046628079453, 0.00771804577106646, 0.00248600917371134]

base_inc_rate_ALRI_by_Enterobacteriaceae

baseline incidence of Alri caused by Enterobacteriaceae in age groups 0-11, 12-23, 24-59 months, per child per year

List

[0.00577447898013911, 0.00776959582619209, 0.002502613624339]

base_inc_rate_ALRI_by_other_Strepto_Enterococci

baseline incidence of Alri caused by other streptococci and Enterococci including Streptococcus pyogenes and Enterococcus faecium in age groups 0-11, 12-23, 24-59 months, per child per year

List

[0.00739221008020393, 0.000441075977443103, 0.000142072094251877]

base_inc_rate_ALRI_by_Staph_aureus

baseline incidence of Alri caused by Staphylococcus aureus in age groups 0-11, 12-23, 24-59 months, per child per year

List

[0.0230583713892271, 0.00164959730828988, 0.000531340984878809]

base_inc_rate_ALRI_by_Influenza

baseline incidence of Alri caused by Influenza type A, B, and C in age groups 0-11, 12-23, 24-59 months, per child per year

List

[0.0156895896609387, 0.00577122651203705, 0.00185893197294524]

base_inc_rate_ALRI_by_P.jirovecii

baseline incidence of Alri caused by P. jirovecii in age groups 0-11, 12-23, 24-59 months, per child per year

List

[0.00532021183938121, 0.00406616141018573, 0.00130972462037058]

base_inc_rate_ALRI_by_other_viral_pathogens

baseline incidence of Alri caused by other viral pathogens in age groups 0-11, 12-23, 24-59 months, per child per year

List

[0.0289052989892286, 0.0340001707821008, 0.0109515723253317]

base_inc_rate_ALRI_by_other_bacterial_pathogens

baseline incidence of Alri caused by other viral pathogens in age groups 0-11, 12-23, 24-59 months, per child per year

List

[0.0340967151177136, 0.0275272316777052, 0.00886661630515269]

base_inc_rate_ALRI_by_other_pathogens_NoS

baseline incidence of Alri caused by other pathogens not otherwise specified in age groups 0-11, 12-23, 24-59 months, per child per year

List

[0.012096954443426, 0.0244908799021158, 0.00788859692140824]

proportion_pneumonia_in_RSV_ALRI

proportion of RSV-attributed ALRI manifesting as pneumonia by age, (based on PERCH CXR+ results)

List

[0.469523118748083, 0.493147834326293]

proportion_pneumonia_in_Rhinovirus_ALRI

proportion of Rhinovirus-attributed ALRI manifesting as pneumonia by age, (based on PERCH CXR+ results)

List

[0.233411098940226, 0.300943850285401]

proportion_pneumonia_in_HMPV_ALRI

proportion of HMPV-attributed ALRI manifesting as pneumonia by age, (based on PERCH CXR+ results)

List

[0.514096212711081, 0.607661832402657]

proportion_pneumonia_in_Parainfluenza_ALRI

proportion of Parainfluenza-attributed ALRI manifesting as pneumonia by age, (based on PERCH CXR+ results)

List

[0.381306534835401, 0.586394378700289]

proportion_pneumonia_in_Strep_pneumoniae_PCV13_ALRI

proportion of S. pneumoniae PCV13-type-attributed ALRI manifesting as pneumonia by age, (based on PERCH CXR+ results)

List

[0.419837201436785, 1]

proportion_pneumonia_in_Strep_pneumoniae_non_PCV13_ALRI

proportion of S. pneumoniae non PCV13-type-attributed ALRI manifesting as pneumonia by age, (based on PERCH CXR+ results)

List

[0.584526531211357, 0.47010416567094]

proportion_pneumonia_in_Hib_ALRI

proportion of Hib ALRI-attributed ALRI manifesting as pneumonia by age, (based on PERCH CXR+ results)

List

[0.643816417750475, 0.591228432603006]

proportion_pneumonia_in_H.influenzae_non_type_b_ALRI

proportion of H.influenzae non type-b-attributed ALRI manifesting as pneumonia by age, (based on PERCH CXR+ results)

List

[0.484067635967411, 0.685783925920651]

proportion_pneumonia_in_Staph_aureus_ALRI

proportion of S. aureus-attributed ALRI manifesting as pneumonia by age, (based on PERCH CXR+ results)

List

[0.314311461687961, 0.668460076932899]

proportion_pneumonia_in_Enterobacteriaceae_ALRI

proportion of Enterobacteriaceae-attributed ALRI manifesting as pneumonia by age, (based on PERCH CXR+ results)

List

[0.542743088827561, 0.397386416381317]

proportion_pneumonia_in_other_Strepto_Enterococci_ALRI

proportion of other Streptococci- and Enterococci-attributed ALRI manifesting as pneumoniaby age, (based on PERCH CXR+ results)

List

[0.794939501527616, 1]

proportion_pneumonia_in_Influenza_ALRI

proportion of Influenza-attributed ALRI manifesting as pneumonia by age, (based on PERCH CXR+ results)

List

[0.274661773216931, 0.477667070122735]

proportion_pneumonia_in_P.jirovecii_ALRI

proportion of P. jirovecii-attributed ALRI manifesting as pneumonia by age, (based on PERCH CXR+ results)

List

[0.773174448993322, 0.650848699225084]

proportion_pneumonia_in_other_viral_pathogens_ALRI

proportion of other viral pathogens-attributed ALRI manifesting as pneumonia by age, (based on PERCH CXR+ results)

List

[0.264286065267648, 0.301616616612727]

proportion_pneumonia_in_other_bacterial_pathogens_ALRI

proportion of other bacterial pathogens-attributed ALRI manifesting as pneumonia by age, (based on PERCH CXR+ results)

List

[0.321708555070697, 0.424616377668989]

proportion_pneumonia_in_other_pathogens_NoS_ALRI

proportion of other pathogens NoS-attributed ALRI manifesting as pneumonia by age, (based on PERCH CXR+ results)

List

[0.323847892119005, 0.256639724815326]

rr_ALRI_HIV/AIDS

relative rate of acquiring Alri for children with HIV+/AIDS

Real

6.51

rr_ALRI_incomplete_measles_immunisation

relative rate of acquiring Alri for children with incomplete measles immunisation

Real

1.8

rr_ALRI_low_birth_weight

relative rate of acquiring Alri for infants with low birth weight

Real

3.6

rr_ALRI_non_exclusive_breastfeeding

relative rate of acquiring Alri for not exclusive breastfeeding upto 6 months

Real

2.7

rr_ALRI_indoor_air_pollution

relative rate of acquiring Alri for indoor air pollution

Real

1.57

prob_viral_pneumonia_bacterial_coinfection

probability of primary viral pneumonia having a bacterial co-infection

Real

0.3

proportion_bacterial_coinfection_pathogen

list of proportions of each bacterial pathogens in a viral/bacterial co-infection pneumonia,the current values used are the pathogen attributable fractions (AFs) from PERCH for all ages. The AFs were scaled to bacterial pathogens only causes - value assumed to be the proportions of bacterial pathogens causing co-/secondary infection

List

[0.107, 0.072, 0.038, 0.141, 0.134, 0.117, 0.052, 0.338]

max_alri_duration_in_days_without_treatment

maximum duration in days of untreated ALRI episode, assuming an average of 7 days

Real

14.0

overall_progression_to_severe_ALRI

probability of progression to severe ALRI

Real

0.12

prob_pulmonary_complications_in_pneumonia

probability of pulmonary complications in (CXR+) pneumonia

Real

0.215

prob_pleural_effusion_in_pulmonary_complicated_pneumonia

probability of pleural effusion in pneumonia with pulmonary complications

Real

0.938

prob_empyema_in_pulmonary_complicated_pneumonia

probability of empyema in pneumonia with pulmonary complications

Real

0.315

prob_lung_abscess_in_pulmonary_complicated_pneumonia

probability of lung abscess in pneumonia with pulmonary complications

Real

0.049

prob_pneumothorax_in_pulmonary_complicated_pneumonia

probability of pneumothorax in pneumonia with pulmonary complications

Real

0.049

prob_hypoxaemia_in_pneumonia

probability of hypoxaemia in pneumonia cases

Real

0.479

prob_hypoxaemia_in_other_alri

probability of hypoxaemia in bronchiolitis and other alri cases

Real

0.273

prob_bacteraemia_in_pneumonia

probability of bacteraemia in pneumonia

Real

0.039

prob_progression_to_sepsis_with_bacteraemia

probability of progression to sepsis from bactereamia

Real

0.3

proportion_hypoxaemia_with_SpO2<90%

proportion of hypoxaemic children with SpO2 <90%

Real

0.3576

scaler_on_risk_of_death

Multiplicative scaler on the overall risk of death, for the purpose of calibration.

Real

0.75

base_odds_death_ALRI_age<2mo

baseline odds of death from ALRI for young infants aged 0 month and severe pneumonia (base group)

Real

0.041965

or_death_ALRI_age<2mo_very_severe_pneumonia

odds ratio of death from ALRI for young infants with very severe pneumonia

Real

3.994783

or_death_ALRI_age<2mo_P.jirovecii

odds ratio of death from ALRI for young infants with P. jirovecii infection

Real

5.460986

or_death_ALRI_age<2mo_by_month_increase_in_age

odds ratio of death from ALRI for young infants by 1 month increase in age (1 month olds)

Real

0.6033254

base_odds_death_ALRI_age2_59mo

baseline odds of death from ALRI for children aged 2 months, male, no SAM, and non-severe pneumonia classification (base group)

Real

0.0244725

or_death_ALRI_age2_59mo_female

odds ratio of death from ALRI for children who are female

Real

1.327285

or_death_ALRI_age2_59mo_very_severe_pneumonia

odds ratio of death from ALRI for children with very severe pneumonia

Real

8.382832

or_death_ALRI_age2_59mo_P.jirovecii

odds ratio of death from ALRI for children with P. jirovecii infection

Real

13.74696

or_death_ALRI_age2_59mo_by_month_increase_in_age

odds ratio of death from ALRI by 1 month increase in age for 2 to 59 months olds

Real

0.9661072

or_death_ALRI_age2_59mo_SAM

odds ratio of death from ALRI for children with severe acute malnutrition

Real

7.216448

or_death_ALRI_SpO2<90%

odds ratio of death from ALRI for children with oxygen saturation < 90%, base group: SpO2 <=93%

Real

5.04

or_death_ALRI_SpO2_90_92%

odds ratio of death from ALRI for children with oxygen saturation between 09 to 92%, base group: SpO2 <=93%

Real

1.54

or_death_ALRI_sepsis

odds ratio of death from ALRI for children with complication of sepsis (compared to if not)

Real

151.9

or_death_ALRI_pneumothorax

odds ratio of death from ALRI for children with complication of pneumothorax (compared to if not)

Real

77.4

prob_cough_in_pneumonia

probability of cough in pneumonia

Real

1.0

prob_difficult_breathing_in_pneumonia

probability of difficulty breathing in pneumonia

Real

1.0

prob_fever_in_pneumonia

probability of fever in pneumonia

Real

0.82

prob_chest_indrawing_in_pneumonia

probability of chest indrawing in pneumonia

Real

0.74

prob_tachypnoea_in_pneumonia

probability of tachypnoea in pneumonia

Real

0.834

prob_danger_signs_in_pneumonia

probability of any danger sign in pneumonia, including: : unable to drink, convulsions, cyanosis, head nodding/bobbing, irritability, abnormally sleepy, lethargy, nasal flaring, grunting

Real

0.28

prob_cough_in_other_alri

probability of cough in bronchiolitis or other alri

Real

1.0

prob_difficult_breathing_in_other_alri

probability of difficulty breathing in bronchiolitis or other alri

Real

1.0

prob_fever_in_other_alri

probability of fever in bronchiolitis or other alri

Real

0.76

prob_tachypnoea_in_other_alri

probability of tachypnoea in bronchiolitis or other alri

Real

0.758

prob_chest_indrawing_in_other_alri

probability of chest wall indrawing in bronchiolitis or other alri

Real

0.33

prob_danger_signs_in_other_alri

probability of any danger signs in bronchiolitis or other alri

Real

0.3

prob_danger_signs_in_sepsis

probability of any danger signs in ALRI complicated by sepsis

Real

1.0

prob_danger_signs_in_SpO2<90%

probability of any danger signs in children with SpO2 <90%

Real

0.313

prob_danger_signs_in_SpO2_90-92%

probability of any danger signs in children with SpO2 between 90-92%

Real

0.133

prob_chest_indrawing_in_SpO2<90%

probability of chest indrawing in children with SpO2 <90%

Real

0.701

prob_chest_indrawing_in_SpO2_90-92%

probability of chest indrawing in children with SpO2 between 90-92%

Real

0.445

prob_cyanosis_in_other_alri

probability of cyanosis in bronchiolitis or other alri

Real

0.04

prob_cyanosis_in_pneumonia

probability of cyanosis in pneumonia

Real

0.06

prob_cyanosis_in_SpO2<90%

probability of cyanosis when SpO2 < 90%

Real

0.078

rr_Strep_pneum_VT_ALRI_with_PCV13_age<2y

relative rate of acquiring S. pneumoniae vaccine-type Alri for children under 2 years of age immunised wth PCV13

Real

0.18

rr_Strep_pneum_VT_ALRI_with_PCV13_age2to5y

relative rate of acquiring S. pneumoniae vaccine-type Alri for children aged 2 to 5 immunised wth PCV13

Real

0.32

rr_all_strains_Strep_pneum_ALRI_with_PCV13

relative rate of acquiring S. pneumoniae all types Alri for children immunised wth PCV13

Real

0.45

effectiveness_Hib_vaccine_on_Hib_strains

effectiveness of Hib vaccine against H. influenzae typ-b ALRI

Real

0.86

rr_Hib_ALRI_with_Hib_vaccine

relative rate of acquiring H. influenzae type-b Alri for children immunised wth Hib vaccine

Real

0.14

days_between_treatment_and_cure

number of days between any treatment being given in an HSI and the cure occurring.

Integer

28

tf_1st_line_antibiotic_for_severe_pneumonia

Risk of treatment failure for a person with danger_signs_pneumonia being treated with first lineintravenous antibiotics

Real

0.11

rr_tf_1st_line_antibiotics_if_cyanosis

Relative Risk for treatment failure for persons with danger_signs_pneumonia being treated with first line intravenous antibiotics if the person has the symptom of cyanosis.having that symptom.

Real

1.55

rr_tf_1st_line_antibiotics_if_SpO2<90%

Relative Risk for treatment failure for persons with danger_signs_pneumonia being treated with first line intravenous antibiotics if the person has oxygen saturation < 90%.

Real

1.28

rr_tf_1st_line_antibiotics_if_abnormal_CXR

Relative Risk for treatment failure for persons with danger_signs_pneumonia being treated with first line intravenous antibiotics if the person has a disease_type of “pneumonia”.

Real

1.71

rr_tf_1st_line_antibiotics_if_MAM

Relative Risk for treatment failure for persons with danger_signs_pneumonia being treated with first line intravenous antibiotics if the person has un_clinical_acute_malnutrition == “MAM”.

Real

1.48

rr_tf_1st_line_antibiotics_if_SAM

Relative Risk for treatment failure for persons with danger_signs_pneumonia being treated with first line intravenous antibiotics if the person has un_clinical_acute_malnutrition == “SAM”.

Real

2.02

rr_tf_1st_line_antibiotics_if_HIV/AIDS

Relative Risk for treatment failure for persons with danger_signs_pneumonia being treated with first line intravenous antibiotics if the person has HIV and is not currently being treated.

Real

1.8

or_mortality_improved_oxygen_systems

Odds Ratio for the effect of oxygen provision to a person that needs oxygen who receives it, compares to a patient who does not. N.B. The inverse of this is used to reflect the increase in odds of death for a patient that needs oxygen but does not receive it.

Real

0.52

tf_3day_amoxicillin_for_fast_breathing_with_SpO2>=90%

probability of treatment failure by day 6 or relapse by day 14 of 3-day course amoxicillin for treating fast-breathing pneumonia

Real

0.101

tf_3day_amoxicillin_for_chest_indrawing_with_SpO2>=90%

probability of treatment failure by day 6 or relapse by day 14 of 3-day course amoxicillin for treating chest-indrawing pneumonia without hypoxaemia (SpO2>=90%)

Real

0.125

tf_5day_amoxicillin_for_chest_indrawing_with_SpO2>=90%

probability of treatment failure by day 6 or relapse by day 14 of 5-day course amoxicillin for treating chest-indrawing pneumonia without hypoxaemia (SpO2>=90%)

Real

0.108

tf_7day_amoxicillin_for_fast_breathing_pneumonia_in_young_infants

probability of treatment failure by day 6 or relapse by day 14 of 5-day course amoxicillin for treating chest-indrawing pneumonia without hypoxaemia (SpO2>=90%)

Real

0.054

tf_oral_amoxicillin_only_for_severe_pneumonia_with_SpO2>=90%

probability of treatment failure by day 2 for oral amoxicillin given to severe pneumonia (danger-signs) without hypoxaemia (SpO2>=93%)

Real

0.6

tf_oral_amoxicillin_only_for_non_severe_pneumonia_with_SpO2<90%

probability of treatment failure or relapsefor oral amoxicillin given to non-severe pneumonia (fast-breathing or chest-indrawing) with hypoxaemia (SpO2<90%)

Real

0.2826

tf_oral_amoxicillin_only_for_severe_pneumonia_with_SpO2<90%

probability of treatment failure or relapsefor oral amoxicillin given to severe pneumonia (danger-signs) with hypoxaemia (SpO2<90%)

Real

0.8

tf_2nd_line_antibiotic_for_severe_pneumonia

probability of treatment failure by end of IV therapy for 2nd line antibiotic either cloxacillin or ceftriaxone to treat severe pneumonia (danger-signs)

Real

0.235

sensitivity_of_classification_of_fast_breathing_pneumonia_facility_level0

sensitivity of correct classification and treatment decision by the HSA trained in iCCM, using paper-based tools, for fast-breathing pneumonia

Real

0.7

sensitivity_of_classification_of_danger_signs_pneumonia_facility_level0

sensitivity of correct classification and referral decision by the HSA trained in iCCM, using paper-based tools, for danger-signs pneumonia

Real

0.7

sensitivity_of_classification_of_non_severe_pneumonia_facility_level1

sensitivity of correct classification and treatment decision for non-severe pneumonia at facility level 1a and 1b

Real

0.7

sensitivity_of_classification_of_severe_pneumonia_facility_level1

sensitivity of correct classification and referral decision for severe pneumonia at facility level 1a and 1b

Real

0.7

sensitivity_of_classification_of_non_severe_pneumonia_facility_level2

sensitivity of correct classification and treatment decision for non-severe pneumonia at facility level 2

Real

0.7

sensitivity_of_classification_of_severe_pneumonia_facility_level2

sensitivity of correct classification and treatment decision for severe pneumonia at facility level 2

Real

0.7

prob_iCCM_severe_pneumonia_treated_as_fast_breathing_pneumonia

probability of misdiagnosis of iCCM severe pneumonia (with chest-indrawing or danger signs) given treatment for non-severe pneumonia (fast-breathing) at facility level O

Real

0.7

prob_IMCI_severe_pneumonia_treated_as_non_severe_pneumonia

probability of misdiagnosis of IMCI severe pneumonia (with danger signs) given treatment for non-severe pneumonia ( fast-breathing or chest-indrawing) at facility level 1a/1b/2

Real

0.7

or_care_seeking_perceived_severe_illness

The Odds Ratio for healthcare seeking for the symptom of chest-indrawing

Real

2.4

pulse_oximeter_and_oxygen_is_available

Control the availability of the pulse oximeter and oxygen. “Default” does not over-ride availability; “Yes” forces them to be available; “No” forces them to not be available

Categorical

Default

prob_for_followup_if_treatment_failure

The probability for scheduling a follow-up appointment following treatment failure

Real

0.3

BladderCancer

Name

Description

Type

Value

init_prop_bladder_cancer_stage

initial proportions in bladder cancer categories for person aged 15-19 and no tobacco and no schisto_h

List

[5e-05, 5e-05, 5e-05]

init_prop_blood_urine_bladder_cancer_by_stage

initial proportions of those with bladder cancer categories that have the symptom blood urine

List

[0.2, 0.5, 0.7]

init_prop_pelvic_pain_bladder_cancer_by_stage

initial proportions of those with bladder cancer categories that have pelvic pain

List

[0.0, 0.3, 0.5]

init_prop_with_blood_urine_diagnosed_bladder_cancer_by_stage

initial proportions of people that have symptom of blood urine that have been diagnosed

List

[0.7, 0.9, 0.9]

init_prop_with_pelvic_pain_diagnosed_bladder_cancer_by_stage

initial proportions of people that have symptom of pelvic pain that have been diagnosed

List

[0.0, 0.7, 0.9]

init_prop_treatment_status_bladder_cancer

initial proportions of people with bladder cancer that had initiated treatment

List

[0.05, 0.05, 0.05]

init_prob_palliative_care

initial probability of being under palliative care if in metastatic

Real

0.95

r_tis_t1_bladder_cancer_none

probability per 3 months of incident tis_t1 bladder cancer, amongst people with no bladder cancer(for person aged 15-19 and no tobacco and no schisto_h)

Real

1e-05

rr_tis_t1_bladder_cancer_none_age3049

rate ratio for tis_t1 bladder cancer for age 30-49

Real

2.0

rr_tis_t1_bladder_cancer_none_age5069

rate ratio for tis_t1 bladder cancer for age 50-69

Real

3.0

rr_tis_t1_bladder_cancer_none_agege70

rate ratio for tis_t1 bladder cancer for age 70+

Real

3.0

rr_tis_t1_bladder_cancer_none_tobacco

rate ratio for tis_t1 bladder cancer for tobacco smokers

Real

3.5

rr_tis_t1_bladder_cancer_none_schisto_h

rate ratio for tis_t1 bladder cancer for schisto_h

Real

5.0

r_t2p_bladder_cancer_tis_t1

probability per 3 months of t2+ bladder cancer, amongst people with tis_t1 bladder cancer

Real

0.05

rr_t2p_bladder_cancer_undergone_curative_treatment

rate ratio for t2+ bladder cancer for people with tis_t1 bladder cancer if had curative treatment at tis_t1 bladder cancer stage

Real

0.1

r_metastatic_t2p_bladder_cancer

probability per 3 months of metastatic bladder cancer amongst people with t2+ bladder cancer

Real

0.05

rr_metastatic_undergone_curative_treatment

rate ratio for metastatic bladder cancer for people with t2+ bladder cancer if had curative treatment at t2+ bladder cancer stage

Real

0.2

rate_palliative_care_metastatic

prob palliative care this 3 month period if metastatic bladder cancer

Real

0.2

r_death_bladder_cancer

probability per 3 months of death from bladder cancer amongst people with metastatic bladder cancer

Real

0.05

r_blood_urine_tis_t1_bladder_cancer

probability per 3 months of blood_urine in a person with tis_t1 bladder cancer

Real

0.01

rr_blood_urine_t2p_bladder_cancer

rate ratio for blood_urine if have t2p bladder cancer

Real

3.0

rr_blood_urine_metastatic_bladder_cancer

rate ratio for blood_urine if have metastatic bladder cancer

Real

3.0

r_pelvic_pain_tis_t1_bladder_cancer

probability per 3 months of pelvic_pain in a person with tis_t1 bladder cancer

Real

0.0003

rr_pelvic_pain_t2p_bladder_cancer

rate ratio for pelvic_pain if have t2p bladder cancer

Real

200.0

rr_pelvic_pain_metastatic_bladder_cancer

rate ratio for pelvic_pain if have metastatic bladder cancer

Real

300.0

rp_bladder_cancer_age3049

relative prevalence at baseline of bladder cancer/cancer age 30-49

Real

2.0

rp_bladder_cancer_age5069

relative prevalence at baseline of bladder cancer/cancer age 50-69

Real

3.0

rp_bladder_cancer_agege70

relative prevalence at baseline of bladder cancer/cancer age 70+

Real

3.0

rp_bladder_cancer_tobacco

relative prevalence at baseline of bladder cancer if tobacco

Real

3.5

rp_bladder_cancer_schisto_h

relative prevalence at baseline of bladder cancer if schisto_h

Real

5.0

sensitivity_of_cystoscopy_for_bladder_cancer_blood_urine

sensitivity of cystoscopy_for diagnosis of bladder cancer given blood urine

Real

1.0

sensitivity_of_cystoscopy_for_bladder_cancer_pelvic_pain

sensitivity of cystoscopy_for diagnosis of bladder cancer given pelvic pain

Real

1.0

BreastCancer

Name

Description

Type

Value

init_prop_breast_cancer_stage

initial proportions in cancer categories for woman aged 15-29

List

[5e-05, 5e-05, 5e-05, 1.5e-05]

init_prop_breast_lump_discernible_breast_cancer_by_stage

initial proportions of those with cancer categories that have the symptom breast_lump_discernible

List

[0.5, 0.8, 0.9, 0.98]

init_prop_with_breast_lump_discernible_diagnosed_breast_cancer_by_stage

initial proportions of people that have breast_lump_discernible that have been diagnosed

List

[0.9, 0.9, 0.9, 0.9]

init_prop_treatment_status_breast_cancer

initial proportions of people with breast cancer previously treated

List

[0.1, 0.1, 0.1, 0.1]

init_prob_palliative_care

initial probability of being under palliative care if in stage 4

Real

0.8

r_stage1_none

probabilty per 3 months of incident stage 1 breast, amongst people with no breast cancer

Real

2e-06

rr_stage1_none_age3049

rate ratio for stage1 breast cancer for age 30-49

Real

20.0

rr_stage1_none_agege50

rate ratio for stage1 breast cancer for age 50+

Real

20.0

r_stage2_stage1

probabilty per 3 months of stage 2 breast cancer amongst people with stage 1

Real

0.15

rr_stage2_undergone_curative_treatment

rate ratio for stage 2 breast cancer for people with stage 1 breast cancer if had curative treatment at stage 1

Real

0.05

r_stage3_stage2

probabilty per 3 months of stage 3 breast cancer amongst people with stage 2

Real

0.15

rr_stage3_undergone_curative_treatment

rate ratio for stage 3 breast cancer for people with stage 2 breast cancer if had curative treatment at stage 2

Real

0.05

r_stage4_stage3

probabilty per 3 months of stage 4 breast cancer amongst people with stage 3

Real

0.15

rr_stage4_undergone_curative_treatment

rate ratio for stage 4 breast cancer for people with stage 3 breast cancer if had curative treatment at stage 3

Real

0.5

r_death_breast_cancer

probabilty per 3 months of death from breast cancer amongst people with stage 4 breast cancer

Real

0.1

r_breast_lump_discernible_stage1

rate ratio for breast_lump_discernible if have stage 1 breast cancer

Real

0.05

rr_breast_lump_discernible_stage2

rate ratio for breast_lump_discernible if have stage 2 breast cancer

Real

2.0

rr_breast_lump_discernible_stage3

rate ratio for breast_lump_discernible if have stage 3 breast cancer

Real

4.0

rr_breast_lump_discernible_stage4

rate ratio for breast_lump_discernible if have stage 4 breast cancer

Real

10.0

rp_breast_cancer_age3049

relative prevalence at baseline of breast cancer if age3049

Real

20.0

rp_breast_cancer_agege50

relative prevalence at baseline of breast cancer if agege50

Real

20.0

sensitivity_of_biopsy_for_stage1_breast_cancer

sensitivity of biopsy_for diagnosis of stage 1 breast cancer

Real

0.8

sensitivity_of_biopsy_for_stage2_breast_cancer

sensitivity of biopsy_for diagnosis of stage 2 breast cancer

Real

0.95

sensitivity_of_biopsy_for_stage3_breast_cancer

sensitivity of biopsy_for diagnosis of stage 3 breast cancer

Real

0.95

sensitivity_of_biopsy_for_stage4_breast_cancer

sensitivity of biopsy_for diagnosis of stage 4 breast cancer

Real

0.95

CardioMetabolicDisorders

Name

Description

Type

Value

diabetes_onset

all the parameters that specify the linear models for onset of diabetes

Series

hypertension_onset

all the parameters that specify the linear models for onset of hypertension

Series

chronic_kidney_disease_onset

all the parameters that specify the linear models for onset of chronic_kidney_disease

Series

chronic_lower_back_pain_onset

all the parameters that specify the linear models for onset of chronic_lower_back_pain

Series

chronic_ischemic_hd_onset

all the parameters that specify the linear models for onset of chronic_ischemic_hd

Series

diabetes_removal

all the parameters that specify the linear models for removal of diabetes

Series

hypertension_removal

all the parameters that specify the linear models for removal of hypertension

Series

chronic_kidney_disease_removal

all the parameters that specify the linear models for removal of chronic_kidney_disease

Series

chronic_lower_back_pain_removal

all the parameters that specify the linear models for removal of chronic_lower_back_pain

Series

chronic_ischemic_hd_removal

all the parameters that specify the linear models for removal of chronic_ischemic_hd

Series

diabetes_hsi

all the parameters that specify diagnostic tests and treatments for diabetes

Series

hypertension_hsi

all the parameters that specify diagnostic tests and treatments for hypertension

Series

chronic_kidney_disease_hsi

all the parameters that specify diagnostic tests and treatments for chronic_kidney_disease

Series

chronic_lower_back_pain_hsi

all the parameters that specify diagnostic tests and treatments for chronic_lower_back_pain

Series

chronic_ischemic_hd_hsi

all the parameters that specify diagnostic tests and treatments for chronic_ischemic_hd

Series

ever_stroke_onset

all the parameters that specify the linear models for onset of ever_stroke

Series

ever_heart_attack_onset

all the parameters that specify the linear models for onset of ever_heart_attack

Series

diabetes_death

all the parameters that specify the linear models for death from diabetes

Series

hypertension_death

all the parameters that specify the linear models for death from hypertension

Series

chronic_kidney_disease_death

all the parameters that specify the linear models for death from chronic_kidney_disease

Series

chronic_lower_back_pain_death

all the parameters that specify the linear models for death from chronic_lower_back_pain

Series

chronic_ischemic_hd_death

all the parameters that specify the linear models for death from chronic_ischemic_hd

Series

ever_stroke_death

all the parameters that specify the linear models for death from ever_stroke

Series

ever_heart_attack_death

all the parameters that specify the linear models for death from ever_heart_attack

Series

ever_stroke_hsi

all the parameters that specify diagnostic tests and treatments for ever_stroke

Series

ever_heart_attack_hsi

all the parameters that specify diagnostic tests and treatments for ever_heart_attack

Series

diabetes_initial_prev

initial prevalence of condition

Series

hypertension_initial_prev

initial prevalence of condition

Series

chronic_kidney_disease_initial_prev

initial prevalence of condition

Series

chronic_lower_back_pain_initial_prev

initial prevalence of condition

Series

chronic_ischemic_hd_initial_prev

initial prevalence of condition

Series

interval_between_polls

months between the main polling event

Integer

3

pr_bmi_reduction

probability of an individual having a reduction in BMI following weight loss treatment

Real

0.1

prob_care_provided_given_seek_emergency_care

The probability that correct care is fully provided to persons that have sought emergency care for a Cardio-metabolic disorder.

Real

0.5

diabetes_onset

value

1.15

0

0

0

0

1

1

1.6

2.21538

Only first 10 rows of 67 are shown.

hypertension_onset

value

0.95

0

0

0

0

0.337838

1.00338

1.00338

1

Only first 10 rows of 67 are shown.

chronic_kidney_disease_onset

value

1.25

0

0

0

0

0.515464

0.515464

0.515464

1

Only first 10 rows of 67 are shown.

chronic_lower_back_pain_onset

value

1

0

0

0

0

0.69

1

1.44615

2.21538

Only first 10 rows of 67 are shown.

chronic_ischemic_hd_onset

value

2.3

0

0

0

0

0.140136

1

1

1

Only first 10 rows of 67 are shown.

diabetes_removal

value

0

0

0

0

0

0

0

0

0

Only first 10 rows of 67 are shown.

hypertension_removal

value

0

0

0

0

0

0

0

0

0

Only first 10 rows of 67 are shown.

chronic_kidney_disease_removal

value

0

0

0

0

0

0

0

0

0

Only first 10 rows of 67 are shown.

chronic_lower_back_pain_removal

value

0.8

0

0

0

0

1

1

1

1

Only first 10 rows of 67 are shown.

chronic_ischemic_hd_removal

value

0

0

0

0

0

0

0

0

0

Only first 10 rows of 67 are shown.

diabetes_hsi

value

216

1

233

0.1

0.42

0.3846

0.8

hypertension_hsi

value

1

221

0.05

0

0.3797

0.8

chronic_kidney_disease_hsi

value

47

1

2064

0

0

0.02

0.8

chronic_lower_back_pain_hsi

value

1

226

0

0

0

0.1

chronic_ischemic_hd_hsi

value

1

226

0

0

0.05

0.8

ever_stroke_onset

value

0.9

0

0

0

0

0.15

0.15

0.15

0.17

Only first 10 rows of 67 are shown.

ever_heart_attack_onset

value

1.5

0

0

0

0

0.05

0.05

0.05

0.05

Only first 10 rows of 67 are shown.

diabetes_death

value

3.2

0

0

0

0

0.2

0.2

0.25

0.25

Only first 10 rows of 67 are shown.

hypertension_death

value

0

0

0

0

0

0

0

0

0

Only first 10 rows of 67 are shown.

chronic_kidney_disease_death

value

2.2

0

0

0

0

0.25

0.2

0.2

0.3

Only first 10 rows of 67 are shown.

chronic_lower_back_pain_death

value

0

0

0

0

0

0

0

0

0

Only first 10 rows of 67 are shown.

chronic_ischemic_hd_death

value

1.4

0

0

0

0

0.673277

0.673277

0.615122

0.641215

Only first 10 rows of 67 are shown.

ever_stroke_death

value

1

0

0

0

0

0.2

0.2

0.35

0.35

Only first 10 rows of 67 are shown.

ever_heart_attack_death

value

1.8

0

0

0

0

0.1

0.1

0.15

0.15

Only first 10 rows of 67 are shown.

ever_stroke_hsi

value

1

226

0

234

0.59

ever_heart_attack_hsi

value

1

226

0

225

0.481

diabetes_initial_prev

value

0

0

0

0.00168696

0.00168696

0.0100913

0.0100913

0.0203044

0.0203044

Only first 10 rows of 42 are shown.

hypertension_initial_prev

value

0

0

0

0.0468696

0.0468696

0.101778

0.101778

0.128891

0.128891

Only first 10 rows of 42 are shown.

chronic_kidney_disease_initial_prev

value

0

0

0

0.0003

0.0003

0.0009

0.0009

0.0033

0.0033

Only first 10 rows of 42 are shown.

chronic_lower_back_pain_initial_prev

value

0.0053

0.0229

0.0341

0.0411

0.0534

0.0657

0.0819

0.0973

0.1095

Only first 10 rows of 42 are shown.

chronic_ischemic_hd_initial_prev

value

0

0

0.0001

0.0005

0.0015

0.0033

0.0065

0.0125

0.0225

Only first 10 rows of 42 are shown.

CareOfWomenDuringPregnancy

Name

Description

Type

Value

prob_seek_anc2

Probability a woman who is not predicted to attended four or more ANC visits will attend ANC2

List

[0.98, 0.98]

prob_seek_anc3

Probability a woman who is not predicted to attended four or more ANC visits will attend ANC3

List

[0.55, 0.55]

prob_seek_anc5

Probability a woman who is predicted to attend four or more ANC visits will attend ANC5

List

[0.125, 0.125]

prob_seek_anc6

Probability a woman who is predicted to attend four or more ANC visits will attend ANC6

List

[0.0625, 0.0625]

prob_seek_anc7

Probability a woman who is predicted to attend four or more ANC visits will attend ANC7

List

[0.03125, 0.03125]

prob_seek_anc8

Probability a woman who is predicted to attend four or more ANC visits will attend ANC8

List

[0.03125, 0.03125]

effect_of_ifa_for_resolving_anaemia

treatment effectiveness of starting iron and folic acid on resolving anaemia

List

[0.7, 0.7]

treatment_effect_blood_transfusion_anaemia

treatment effectiveness of blood transfusion for anaemia in pregnancy

List

[0.9, 0.9]

prob_intervention_delivered_urine_ds

probability a woman will receive the intervention “urine dipstick” given that the HSI has ran and the consumables are available (proxy for clinical quality)

List

[0.53, 0.53]

prob_intervention_delivered_bp

probability a woman will receive the intervention “blood pressure measurement” given that the HSI has ran and the consumables are available (proxy for clinical quality)

List

[0.7, 0.69]

prob_adherent_ifa

probability a woman who is given iron and folic acid will adhere to the treatment for their pregnancy

List

[0.37, 0.34]

prob_intervention_delivered_syph_test

probability a woman will receive the intervention “Syphilis test” given that the HSI has ran and the consumables are available (proxy for clinical quality)

List

[0.43, 0.14]

prob_intervention_delivered_gdm_test

probability a woman will receive the intervention “GDM screening” given that the HSI has ran and the consumables are available (proxy for clinical quality)

List

[0.48, 0.48]

prob_delivery_modes_ec

probabilities that a woman admitted with eclampsia will deliver normally, via caesarean or via assisted vaginal delivery

List

[[0, 0, 1], [0, 0, 1]]

prob_delivery_modes_spe

probabilities that a woman admitted with severe pre-eclampsia will deliver normally, via caesarean or via assisted vaginal delivery

List

[[0.05, 0.05, 0.9], [0.05, 0.05, 0.9]]

sensitivity_bp_monitoring

sensitivity of blood pressure monitoring to detect hypertension

List

[0.74, 0.74]

specificity_bp_monitoring

specificity of blood pressure monitoring to detect hypertension

List

[0.79, 0.79]

sensitivity_urine_protein_1_plus

sensitivity of a urine dipstick test to detect proteinuria at 1+

List

[0.541, 0.541]

specificity_urine_protein_1_plus

specificity of a urine dipstick test to detect proteinuria at 1+

List

[0.841, 0.841]

sensitivity_poc_hb_test

sensitivity of a point of care Hb test to detect anaemia

List

[0.851, 0.851]

specificity_poc_hb_test

specificity of a point of care Hb test to detect anaemia

List

[0.801, 0.801]

sensitivity_fbc_hb_test

sensitivity of a Full Blood Count test to detect anaemia

List

[1.0, 1.0]

specificity_fbc_hb_test

specificity of a Full Blood Count test to detect anaemia

List

[1.0, 1.0]

sensitivity_blood_test_glucose

sensitivity of a blood test to detect raised blood glucose

List

[1.0, 1.0]

specificity_blood_test_glucose

specificity of a blood test to detect raised blood glucose

List

[1.0, 1.0]

sensitivity_blood_test_syphilis

sensitivity of a blood test to detect syphilis

List

[0.82, 0.82]

specificity_blood_test_syphilis

specificity of a blood test to detect syphilis

List

[0.96, 0.96]

Contraception

Name

Description

Type

Value

Method_Use_In_2010

Proportion of women using each method in 2010, by age.

Dataframe

Pregnancy_NotUsing_In_2010

Probability per year of a women not on contraceptive becoming pregnant, by age.

Dataframe

Pregnancy_NotUsing_HIVeffect

Relative probability of becoming pregnant whilst not using a a contraceptive for HIV-positive women compared to HIV-negative women.

Dataframe

Failure_ByMethod

Probability per month of a women on a contraceptive becoming pregnant, by method.

Dataframe

rr_fail_under25

The relative risk of becoming pregnant whilst using a contraceptive for woman younger than 25 years compared to older women.

Real

2.2

Initiation_ByMethod

Probability per month of a women who is not using any contraceptive method of starting use of a method, by method.

Dataframe

Interventions_Pop

Pop (population scale contraception intervention) intervention multiplier.

Dataframe

Interventions_PPFP

PPFP (post-partum family planning) intervention multiplier.

Dataframe

Initiation_ByAge

The effect of age on the probability of starting use of contraceptive (add one for multiplicative effect).

Dataframe

Initiation_AfterBirth

The probability of a woman starting a contraceptive immidiately after birth, by method.

Dataframe

Discontinuation_ByMethod

The probability per month of discontinuing use of a method, by method.

Dataframe

Discontinuation_ByAge

The effect of age on the probability of discontinuing use of contraceptive (add one for multiplicative effect).

Dataframe

Prob_Switch_From

The probability per month that a women switches from one form of contraceptive to another, conditional that she will not discontinue use of the method.

Dataframe

Prob_Switch_From_And_To

The probability of switching to a new method, by method, conditional that the woman will switch to a new method.

Dataframe

days_between_appts_for_maintenance

The number of days between successive family planning appointments for women that are maintaining the use of a method (for each method insorted(self.states_that_may_require_HSI_to_maintain_on), i.e.[IUD, implant, injections, other_modern, pill]).

List

[4383, 1461, 91, 91, 91, 91]

age_specific_fertility_rates

Data table from official source (WPP) for age-specific fertility rates and calendar period.

Dataframe

scaling_factor_on_monthly_risk_of_pregnancy

Scaling factor (by age-group: 15-19, 20-24, …, 45-49) on the monthly risk of pregnancy and contraceptive failure rate. This value is found through calibration so that, at the beginning of the simulation, the age-specific monthly probability of a woman having a live birth matches the WPP age-specific fertility rate value for the same year.

List

[1.227, 0.7191, 0.6632, 0.84945, 0.86135, 0.645, 0.941]

max_number_of_runs_of_hsi_if_consumable_not_available

The maximum number of time an HSI can run (repeats occur if the consumables are not available).

Integer

1000

max_days_delay_between_decision_to_change_method_and_hsi_scheduled

The maximum delay (in days) between the decision for a contraceptive to change and the topen date of the HSI that is scheduled to effect the change (when using the healthsystem).

Integer

7

use_interventions

if True: FP interventions (pop & ppfp) are simulated from the date ‘interventions_start_date’, if False: FP interventions (pop & ppfp) are not simulated.

Boolean

False

interventions_start_date

The date since which the FP interventions (pop & ppfp) are implemented, if at all (ie, if use_interventions==True

Date

2023-01-01 00:00:00

Method_Use_In_2010

age

not_using

pill

IUD

injections

implant

male_condom

female_sterilization

other_modern

periodic_abstinence

withdrawal

other_traditional

16

0.956447

0

0.000853971

0.0187874

0

0.0204953

0

0

0.00256191

0

0.000853971

17

0.917373

0.00105932

0

0.0413136

0

0.0275424

0

0

0.00317797

0.00741525

0.00105932

18

0.843715

0.00679502

0

0.103058

0

0.0396376

0

0

0

0.00566251

0

19

0.738693

0.0188442

0

0.182161

0

0.0376884

0

0

0.00125628

0.0138191

0.00251256

20

0.693305

0.0107991

0

0.218143

0

0.0410367

0.00431965

0

0.00215983

0.0215983

0.00323974

21

0.644362

0.0173482

0.00123916

0.272615

0

0.0371747

0.00123916

0

0.00123916

0.00743494

0.00619579

22

0.634744

0.018931

0

0.26392

0

0.0356347

0.00445434

0

0.00556793

0.0155902

0.00668151

23

0.642616

0.00676437

0.00225479

0.264938

0

0.0394588

0.00338219

0

0.00789177

0.0124014

0.00676437

24

0.588101

0.020595

0.00114416

0.286041

0

0.0297483

0.0125858

0

0.00800915

0.0228833

0.00915332

Only first 10 rows of 35 are shown.

Pregnancy_NotUsing_In_2010

age

AnnualProb

16

0.0780862

17

0.148498

18

0.298088

19

0.402345

20

0.532862

21

0.552413

22

0.586474

23

0.569371

24

0.598742

Only first 10 rows of 35 are shown.

Pregnancy_NotUsing_HIVeffect

age_

RR_pregnancy

16

1.4

17

1.4

18

1.4

19

1.4

20

0.9

21

0.9

22

0.9

23

0.9

24

0.9

Only first 10 rows of 35 are shown.

Failure_ByMethod

pill

IUD

injections

implant

male_condom

female_sterilization

other_modern

periodic_abstinence

withdrawal

other_traditional

0.00192848

0

0.000530667

9.50789e-05

0.00117109

0

0

0.000552797

0.00358032

0.004923

Initiation_ByMethod

not_using

pill

IUD

injections

implant

male_condom

female_sterilization

other_modern

periodic_abstinence

withdrawal

other_traditional

0.993934

0.000397942

1.84759e-05

0.00382829

0.000117488

0.000793041

0.000274295

2.5582e-05

9.2853e-05

0.000358621

0.000159177

Interventions_Pop

pill

IUD

injections

implant

male_condom

female_sterilization

other_modern

periodic_abstinence

withdrawal

other_traditional

2.5

11

1.6

8

2.6

2

5

1

1

1

Interventions_PPFP

pill

IUD

injections

implant

male_condom

female_sterilization

other_modern

periodic_abstinence

withdrawal

other_traditional

2.5

11

1.6

8

2.6

2

5

1

1

1

Initiation_ByAge

age

r_init1_age

16

0.224538

17

0.147192

18

0.089718

19

0.0469456

20

0.0151724

21

-0.00829227

22

-0.0254293

23

-0.0377144

24

-0.0462588

Only first 10 rows of 35 are shown.

Initiation_AfterBirth

not_using

pill

IUD

injections

implant

male_condom

female_sterilization

other_modern

periodic_abstinence

withdrawal

other_traditional

0.99654

0.000224019

5.84398e-06

0.00180189

5.06478e-05

0.000210383

0.000718809

1.1688e-05

0.000105192

0.000181163

0.000149995

Discontinuation_ByMethod

pill

IUD

injections

implant

male_condom

female_sterilization

other_modern

periodic_abstinence

withdrawal

other_traditional

0.0496232

0.0111009

0.0333511

0.00627062

0.0503725

0

0.0332874

0.0422692

0.0423377

0.0497931

Discontinuation_ByAge

age

r_discont_age

16

-0.628712

17

-0.438627

18

-0.29471

19

-0.185198

20

-0.101633

21

-0.037841

22

0.0107489

23

0.0475587

24

0.0751794

Only first 10 rows of 35 are shown.

Prob_Switch_From

pill

IUD

injections

implant

male_condom

female_sterilization

other_modern

periodic_abstinence

withdrawal

other_traditional

0.0109093

0.00145124

0.0030322

0.000862686

0.0114341

0

0.00265503

0.00751371

0.0137878

0.027214

Prob_Switch_From_And_To

switchfrom

pill

IUD

injections

implant

male_condom

female_sterilization

other_modern

periodic_abstinence

withdrawal

other_traditional

pill

0

0

0.540323

0.217742

0.104839

0.0564516

0.0241935

0.00806452

0.0403226

0.00806452

IUD

0.125

0

0.375

0.25

0.125

0.125

0

0

0

0

injections

0.262806

0.0267261

0

0.447661

0.106904

0.0757238

0.00890869

0.00890869

0.0445434

0.0178174

implant

0.205882

0.0294118

0.632353

0

0.102941

0.0294118

0

0

0

0

male_condom

0.0829268

0.00487805

0.595122

0.22439

0

0.0292683

0.00487805

0.0097561

0.0487805

0

other_modern

0

0

1

0

0

0

0

0

0

0

periodic_abstinence

0

0

0.333333

0.666667

0

0

0

0

0

0

withdrawal

0.037037

0.0185185

0.518519

0.296296

0.111111

0.0185185

0

0

0

0

other_traditional

0

0

0.73913

0.144928

0.057971

0.057971

0

0

0

0

age_specific_fertility_rates

Variant

Period

Age_Grp

asfr

WPP_Estimates

1955-1959

15-19

0.183883

WPP_Estimates

1960-1964

15-19

0.186647

WPP_Estimates

1965-1969

15-19

0.191979

WPP_Estimates

1970-1974

15-19

0.197259

WPP_Estimates

1975-1979

15-19

0.202538

WPP_Estimates

1980-1984

15-19

0.202538

WPP_Estimates

1985-1989

15-19

0.193211

WPP_Estimates

1990-1994

15-19

0.159343

WPP_Estimates

1995-1999

15-19

0.160904

Only first 10 rows of 434 are shown.

Copd

Name

Description

Type

Value

prob_mod_exacerb

probability of moderate exacerbation given lung function, for each lung function category.

List

[0, 0, 0, 0.01, 0.05, 0.2, 0.3]

prob_sev_exacerb

probability of severe exacerbation given lung function, for each lung function category.

List

[0, 0, 0, 0.0, 0.0, 0.05, 0.1]

prob_progress_to_next_cat

probability of changing from a lower lung function category to a higher lung function category

Real

0.015

prob_will_die_sev_exacerbation_ge80

probability that a person equal to or greater than 80 years will die of severe exacerbation

Real

0.95

prob_will_die_sev_exacerbation_7079

probability that a person between 70 to 79 years will die of severe exacerbation

Real

0.7

prob_will_die_sev_exacerbation_6069

probability that a person between 60 to 99 years will die of severe exacerbation

Real

0.5

prob_will_die_sev_exacerbation_5059

probability that a person between 50 to 59 years will die of severe exacerbation

Real

0.05

prob_will_die_sev_exacerbation_4049

probability that a person between 40 to 49 years will die of severe exacerbation

Real

0.02

prob_will_die_sev_exacerbation_3039

probability that a person between 30 to 39 years will die of severe exacerbation

Real

0.01

prob_will_die_sev_exacerbation_lt30

probability that a person less than 30 years will die of severe exacerbation

Real

0.0

eff_oxygen

the effect of oxygen on individuals with severe exacerbation

Real

0.6

rel_risk_progress_per_higher_cat

relative risk of progression to the next higher level of lung function for each higher level

Real

0.5

rel_risk_tob

relative effect of tobacco on the rate of lung function progression

Real

7.0

rel_risk_wood_burn_stove

relative risk of wood burn stove on the rate of lung function progression

Real

2.0

prob_not_tob_lung_func_15_39

probability of lung function categories in individuals aged 15-39 and do not smoke tobacco

List

[0.496396, 0.337947, 0.114555, 0.040078, 0.010086, 0.000938, 0.0]

prob_not_tob_lung_func_40_59

probability of lung function categories in individuals aged 40-59 and do not smoke tobacco

List

[0.114194, 0.306129, 0.292286, 0.212143, 0.067501, 0.007387, 0.00036]

prob_not_tob_lung_func_gr59

probability of lung function categories in individuals aged 60+ and do not smoke tobacco

List

[0.009201, 0.08707, 0.263341, 0.44523, 0.183632, 0.010073, 0.001453]

prob_tob_lung_func_15_39

probability of lung function categories in individuals aged 15-39 who smoke tobacco

List

[0.06712, 0.199903, 0.259728, 0.241245, 0.148346, 0.071498, 0.01216]

prob_tob_lung_func_40_59

probability of lung function categories in individuals aged 40-59 who smoke tobacco

List

[0.001499, 0.033733, 0.112819, 0.231259, 0.337331, 0.225637, 0.057722]

prob_tob_lung_func_gr59

probability of lung function categories in individuals aged 60+ who smoke tobacco

List

[0.0, 0.0, 0.035366, 0.20122, 0.453659, 0.246341, 0.063414]

Demography

Name

Description

Type

Value

max_age_initial

The oldest age (in whole years) in the initial population

Integer

120

pop_2010

Population in 2010 for initialising population

Dataframe

district_num_to_district_name

Mapping from district_num to district name

Dictionary

district_num_to_region_name

Mapping from district_num to region name

Dictionary

districts_in_region

Set of districts (by name) that are within a region (by name)

Dictionary

all_cause_mortality_schedule

All-cause age-specific mortality rates from WPP

Dataframe

fraction_of_births_male

Birth Sex Ratio

Series

pop_2010

District

District_Num

Region

Sex

Age

Count

Chitipa

0

Northern

M

1

3673.51

Chitipa

0

Northern

M

2

3538.09

Chitipa

0

Northern

M

3

3410.42

Chitipa

0

Northern

M

4

3289.97

Chitipa

0

Northern

M

5

3176.2

Chitipa

0

Northern

M

6

3068.58

Chitipa

0

Northern

M

7

2966.6

Chitipa

0

Northern

M

8

2869.74

Chitipa

0

Northern

M

9

2777.45

Only first 10 rows of 6464 are shown.

district_num_to_district_name

0

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

21

22

23

24

25

26

27

28

29

30

31

Chitipa

Karonga

Nkhata Bay

Rumphi

Mzimba

Likoma

Mzuzu City

Kasungu

Nkhotakota

Ntchisi

Dowa

Salima

Lilongwe

Mchinji

Dedza

Ntcheu

Lilongwe City

Mangochi

Machinga

Zomba

Chiradzulu

Blantyre

Mwanza

Thyolo

Mulanje

Phalombe

Chikwawa

Nsanje

Balaka

Neno

Zomba City

Blantyre City

district_num_to_region_name

0

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

21

22

23

24

25

26

27

28

29

30

31

Northern

Northern

Northern

Northern

Northern

Northern

Northern

Central

Central

Central

Central

Central

Central

Central

Central

Central

Central

Southern

Southern

Southern

Southern

Southern

Southern

Southern

Southern

Southern

Southern

Southern

Southern

Southern

Southern

Southern

districts_in_region

Northern

0

1

2

3

4

5

6

Chitipa

Mzimba

Likoma

Mzuzu City

Nkhata Bay

Karonga

Rumphi

Central

0

1

2

3

4

5

6

7

8

9

Mchinji

Ntchisi

Dedza

Lilongwe

Lilongwe City

Dowa

Nkhotakota

Salima

Ntcheu

Kasungu

Southern

0

1

2

3

4

5

6

7

8

9

10

11

12

13

14

Neno

Chikwawa

Zomba City

Blantyre

Phalombe

Thyolo

Mwanza

Mangochi

Machinga

Mulanje

Balaka

Chiradzulu

Zomba

Blantyre City

Nsanje

all_cause_mortality_schedule

fallbackyear

sex

age_years

death_rate

1950

M

1

0.0572109

1950

M

2

0.0572109

1950

M

3

0.0572109

1950

M

4

0.0572109

1950

M

5

0.0139565

1950

M

6

0.0139565

1950

M

7

0.0139565

1950

M

8

0.0139565

1950

M

9

0.0139565

Only first 10 rows of 7200 are shown.

fraction_of_births_male

frac_births_male

0.50495

0.50495

0.50495

0.50495

0.50495

0.50495

0.50495

0.50495

0.50495

Only first 10 rows of 150 are shown.

Depression

Name

Description

Type

Value

init_pr_depr_m_age1519_no_cc_wealth123

Initial probability of being depressed in male age1519 with no chronic condition with wealth level 1 or 2 or 3

Real

0.06

init_rp_depr_f_not_rec_preg

Initial relative prevalence of being depressed in females not recently pregnant

Real

1.5

init_rp_depr_f_rec_preg

Initial relative prevalence of being depressed in females recently pregnant

Real

3.0

init_rp_depr_age2059

Initial relative prevalence of being depressed in 20-59 year olds vs 15-19

Real

1.0

init_rp_depr_agege60

Initial relative prevalence of being depressed in 60+ year olds vs 15-19

Real

3.0

init_rp_depr_cc

Initial relative prevalence of being depressed in people with chronic condition

Real

1.0

init_rp_depr_wealth45

Initial relative prevalence of being depressed in people with wealth level 4 or 5 vs 1 or 2 or 3

Real

1.0

init_rp_ever_depr_per_year_older_m

Initial relative prevalence ever depression per year older in men

Real

0.004

init_rp_ever_depr_per_year_older_f

Initial relative prevalence ever depression per year older in women

Real

0.006

init_pr_ever_talking_therapy_if_diagnosed

Initial probability of ever having had talking therapy if ever diagnosed with depression

Real

1.0

init_pr_antidepr_curr_depr

Initial probability of being on antidepressants if currently depressed

Real

0.11

init_rp_antidepr_ever_depr_not_curr

Initial relative prevalence of being on antidepressants if ever depressed but not currently

Real

0.5

init_pr_ever_diagnosed_depression

Initial probability of having ever been diagnosed with depression, amongst people with ever depression and not on antidepressants

Real

0.2

init_pr_ever_self_harmed_if_ever_depr

Initial probability of having ever self harmed if ever depressed

Real

0.004

base_3m_prob_depr

Probability of onset of depression in a 3 month period if male, wealth 1 2 or 3, no chronic condition and never previously depressed

Real

0.0021

rr_depr_wealth45

Relative rate of depression when in wealth level 4 or 5 vs 1 or 2 or 3

Real

3.0

rr_depr_cc

Relative rate of depression if has any chronic disease

Real

1.25

rr_depr_pregnancy

Relative rate of depression when pregnant or recently pregnant

Real

3.0

rr_depr_female

Relative rate of depression for females vs males

Real

1.5

rr_depr_prev_epis

Relative rate of depression associated with previous depression vs never previously depressed

Real

50.0

rr_depr_on_antidepr

Relative rate of depression episode if on antidepressants

Real

30.0

rr_depr_age1519

Relative rate of depression associated with 15-20 year olds

Real

1.0

rr_depr_agege60

Relative rate of depression associated with age > 60

Real

3.0

rr_depr_hiv

Relative rate of depression associated with HIV infection

Real

1.99

depr_resolution_rates

Risk of depression resolving in 3 months if no chronic conditions and no treatments.Each individual is equally likely to be assigned each of these risks

List

[0.2, 0.3, 0.5, 0.7, 0.95]

rr_resol_depr_cc

Relative rate of resolving depression if has any chronic disease

Real

0.5

rr_resol_depr_on_antidepr

Relative rate of resolving depression if on antidepressants

Real

1.5

rr_resol_depr_current_talk_ther

Relative rate of resolving depression if has ever had talking therapy vs has never had talking therapy

Real

1.1

prob_3m_stop_antidepr

Probability per 3 months of stopping antidepressants when not currently depressed.

Real

0.7

prob_3m_default_antidepr

Probability per 3 months of stopping antidepressants when still depressed.

Real

0.2

prob_3m_suicide_depr_m

Probability per 3 months of suicide in currently depressed men

Real

0.0005

rr_suicide_depr_f

Relative risk of suicide in women compared with men

Real

0.333

prob_3m_selfharm_depr

Probability per 3 months of non-fatal self harm in those currently depressed

Real

0.0005

sensitivity_of_assessment_of_depression

The sensitivity of the clinical assessment in detecting the true current status of depression

Real

0.75

pr_assessed_for_depression_in_generic_appt_level1

Probability that a person is assessed for depression during a non-emergency generic appointmentlevel 1

Real

0.01

anti_depressant_medication_item_code

The item code used for one month of anti-depressant treatment

Integer

267

pr_assessed_for_depression_for_perinatal_female

Probability that a perinatal female is assessed for depression during antenatal or postnatal services

Real

0.01

Diarrhoea

Name

Description

Type

Value

base_inc_rate_diarrhoea_by_rotavirus

incidence rate (per person-year) of diarrhoea caused by rotavirus in age groups 0-11, 12-23, 24-59 months

List

[0.175245863, 0.097007598, 0.009324]

base_inc_rate_diarrhoea_by_shigella

incidence rate (per person-year) of diarrhoea caused by shigella spp in age groups 0-11, 12-23, 24-59 months

List

[0.117936461999999, 0.078794104, 0.093018]

base_inc_rate_diarrhoea_by_adenovirus

incidence rate (per person-year) of diarrhoea caused by adenovirus 40/41 in age groups 0-11, 12-23, 24-59 months

List

[0.0586618, 0.058661803, 0.006438]

base_inc_rate_diarrhoea_by_cryptosporidium

incidence rate (per person-year) of diarrhoea caused by cryptosporidium in age groups 0-11, 12-23, 24-59 months

List

[0.030886699, 0.0117923629999999, 0.004662]

base_inc_rate_diarrhoea_by_campylobacter

incidence rate (per person-year) of diarrhoea caused by campylobacter spp in age groups 0-11, 12-23, 24-59 months

List

[0.098663257, 0.027915478, 0.004884]

base_inc_rate_diarrhoea_by_ETEC

incidence rate (per person-year) of diarrhoea caused by ETEC in age groups 0-11, 12-23, 24-59 months

List

[0.27925146, 0.170477152, 0.019758]

base_inc_rate_diarrhoea_by_sapovirus

incidence rate (per person-year) of diarrhoea caused by sapovirus in age groups 0-11, 12-23, 24-59 months

List

[0.100972179, 0.132603114, 0.00555]

base_inc_rate_diarrhoea_by_norovirus

incidence rate (per person-year) of diarrhoea caused by norovirus in age groups 0-11, 12-23, 24-59 months

List

[0.204864004, 0.066146727, 0.000888]

base_inc_rate_diarrhoea_by_astrovirus

incidence rate (per person-year) of diarrhoea caused by astrovirus in age groups 0-11, 12-23, 24-59 months

List

[0.054208352, 0.035974076, 0.001332]

base_inc_rate_diarrhoea_by_tEPEC

incidence rate (per person-year) of diarrhoea caused by tEPEC in age groups 0-11, 12-23, 24-59 months

List

[0.0608224569999999, 0.022716889, 0.001998]

rr_diarrhoea_HHhandwashing

relative rate of diarrhoea with household handwashing with soap

Real

0.7

rr_diarrhoea_improved_sanitation

relative rate of diarrhoea for improved sanitation

Real

0.75

rr_diarrhoea_clean_water

relative rate of diarrhoea for access to clean drinking water

Real

0.67

rr_diarrhoea_exclusive_vs_partial_breastfeeding_<6mo

relative rate of diarrhoea for partial breastfeeding in <6 months old, compared to exclusive breastfeeding

Real

1.68

rr_diarrhoea_exclusive_vs_no_breastfeeding_<6mo

relative rate of diarrhoea for no breastfeeding in <6 months old, compared to exclusive breastfeeding

Real

2.65

rr_diarrhoea_any_vs_no_breastfeeding_6_11mo

relative rate of diarrhoea for no breastfeeding in 6 months old to 1 years old, compared to any breastfeeding at this age group

Real

1.32

rr_diarrhoea_untreated_HIV

relative rate of diarrhoea for HIV positive status

Real

5.4

rr_diarrhoea_SAM

relative rate of diarrhoea for severe malnutrition

Real

1.2

proportion_AWD_in_rotavirus

acute diarrhoea type caused in rotavirus-attributed diarrhoea

Real

0.97668

proportion_AWD_in_shigella

acute diarrhoea type caused in shigella-attributed diarrhoea

Real

0.861942

proportion_AWD_in_adenovirus

acute diarrhoea type caused in adenovirus-attributed diarrhoea

Real

0.950061

proportion_AWD_in_cryptosporidium

acute diarrhoea type caused in cryptosporidium-attributed diarrhoea

Real

0.970984

proportion_AWD_in_campylobacter

acute diarrhoea type caused in campylobacter-attributed diarrhoea

Real

0.896768

proportion_AWD_in_ETEC

acute diarrhoea type caused in ETEC-attributed diarrhoea

Real

0.950465

proportion_AWD_in_sapovirus

acute diarrhoea type caused in sapovirus-attributed diarrhoea

Real

0.966385

proportion_AWD_in_norovirus

acute diarrhoea type caused in norovirus-attributed diarrhoea

Real

0.961643

proportion_AWD_in_astrovirus

acute diarrhoea type caused in astrovirus-attributed diarrhoea

Real

0.974147

proportion_AWD_in_tEPEC

acute diarrhoea type in tEPEC-attributed diarrhoea

Real

0.961485

prob_dehydration_by_rotavirus

probability of any dehydration caused by rotavirus

Real

0.153093

prob_dehydration_by_shigella

probability of any dehydration caused by shigella

Real

0.102962

prob_dehydration_by_adenovirus

probability of any dehydration caused by adenovirus

Real

0.079524

prob_dehydration_by_cryptosporidium

probability of any dehydration caused by cryptosporidium

Real

0.121458

prob_dehydration_by_campylobacter

probability of any dehydration caused by campylobacter

Real

0.072808

prob_dehydration_by_ETEC

probability of any dehydration caused by ETEC

Real

0.075925

prob_dehydration_by_sapovirus

probability of any dehydration caused by sapovirus

Real

0.10364

prob_dehydration_by_norovirus

probability of any dehydration caused by norovirus

Real

0.090728

prob_dehydration_by_astrovirus

probability of any dehydration caused by astrovirus

Real

0.122776

prob_dehydration_by_tEPEC

probability of any dehydration caused by tEPEC

Real

0.113362

probability_of_severe_dehydration_if_some_dehydration

probability that someone with diarrhoea and some dehydration develops severe dehydration

Real

0.167

prob_prolonged_diarr_rotavirus

probability of prolonged episode in rotavirus-attributed diarrhoea

Real

0.117706

prob_prolonged_diarr_shigella

probability of prolonged episode by shigella-attributed diarrhoea

Real

0.165342

prob_prolonged_diarr_adenovirus

probability of prolonged episode by adenovirus-attributed diarrhoea

Real

0.116406

prob_prolonged_diarr_cryptosporidium

probability of prolonged episode by cryptosporidium-attributed diarrhoea

Real

0.169134

prob_prolonged_diarr_campylobacter

probability of prolonged episode by campylobacter-attributed diarrhoea

Real

0.152206

prob_prolonged_diarr_ETEC

probability of prolonged episode by ETEC-attributed diarrhoea

Real

0.114177

prob_prolonged_diarr_sapovirus

probability of prolonged episode by sapovirus-attributed diarrhoea

Real

0.133209

prob_prolonged_diarr_norovirus

probability of prolonged episode by norovirus-attributed diarrhoea

Real

0.118223

prob_prolonged_diarr_astrovirus

probability of prolonged episode by norovirus-attributed diarrhoea

Real

0.13511

prob_prolonged_diarr_tEPEC

probability of prolonged episode by tEPEC-attributed diarrhoea

Real

0.190845

prob_prolonged_to_persistent_diarr

probability of prolonged diarrhoea becoming persistent diarrhoea

Real

0.2866

rr_bec_persistent_age>6mo

relative rate of acute diarrhoea becoming persistent diarrhoea for children over 6 months

Real

0.26

rr_bec_persistent_HIV

relative rate of acute diarrhoea becoming persistent diarrhoea for HIV positive

Real

1.7

rr_bec_persistent_SAM

relative rate of acute diarrhoea becoming persistent diarrhoea for severely acute malnutrition

Real

1.7

rr_bec_persistent_stunted

relative rate of acute diarrhoea becoming persistent diarrhoea for stunted children

Real

33.3

min_dur_acute

The minimum duration (in days) for an episode that is classified as an acute episode

Integer

1

min_dur_prolonged

The minimum duration (in days) for an episode that is classified as a prolonged episode

Integer

5

min_dur_persistent

The minimum duration (in days) for an episode that is classified as a persistent episode

Integer

13

max_dur_persistent

The maximum duration (in days) for an episode that is classified as a persistent episode

Integer

30

prob_fever_by_rotavirus

probability of fever caused by rotavirus

Real

0.384925

prob_fever_by_shigella

probability of fever caused by shigella

Real

0.319876

prob_fever_by_adenovirus

probability of fever caused by adenovirus

Real

0.271513

prob_fever_by_cryptosporidium

probability of fever caused by cryptosporidium

Real

0.322385

prob_fever_by_campylobacter

probability of fever caused by campylobacter

Real

0.312807

prob_fever_by_ETEC

probability of fever caused by ETEC

Real

0.258931

prob_fever_by_sapovirus

probability of fever caused by sapovirus

Real

0.292276

prob_fever_by_norovirus

probability of fever caused by norovirus

Real

0.251071

prob_fever_by_astrovirus

probability of fever caused by astrovirus

Real

0.195905

prob_fever_by_tEPEC

probability of fever caused by tEPEC

Real

0.384547

prob_vomiting_by_rotavirus

probability of vomiting caused by rotavirus

Real

0.471793

prob_vomiting_by_shigella

probability of vomiting caused by shigella

Real

0.209852

prob_vomiting_by_adenovirus

probability of vomiting caused by adenovirus

Real

0.308677

prob_vomiting_by_cryptosporidium

probability of vomiting caused by cryptosporidium

Real

0.243581

prob_vomiting_by_campylobacter

probability of vomiting caused by campylobacter

Real

0.218669

prob_vomiting_by_ETEC

probability of vomiting caused by ETEC

Real

0.283139

prob_vomiting_by_sapovirus

probability of vomiting caused by sapovirus

Real

0.303154

prob_vomiting_by_norovirus

probability of vomiting caused by norovirus

Real

0.299343

prob_vomiting_by_astrovirus

probability of vomiting caused by astrovirus

Real

0.276018

prob_vomiting_by_tEPEC

probability of vomiting caused by tEPEC

Real

0.285661

adjustment_factor_on_cfr

Factor by which fatality probabilities are multiplied (to be used in calibration)

Real

3.75

case_fatality_rate_AWD

case fatality rate for acute watery diarrhoea cases

Real

0.0015

rr_diarr_death_bloody

relative risk of diarrhoea death (compared to case_fatality_rate_AWD if the diarrhoea is of type “bloody” (i.e. dyssentry).

Real

7.6

rr_diarr_death_age24to59mo

relative risk of diarrhoea death for ages 24 to 59 months

Real

0.38

rr_diarr_death_if_duration_longer_than_13_days

relative risk of diarrhoea death if the duration episode is 13 days or longer

Real

0.0035

rr_diarr_death_severe_dehydration

relative risk of diarrhoea death for cases with severe dehyadration

Real

3.45

rr_diarr_death_untreated_HIV

relative risk of diarrhoea death for untreated HIV

Real

5.05

rr_diarr_death_SAM

relative risk of diarrhoea death for severe acute malnutrition

Real

4.13

rr_diarr_death_alri

relative risk of diarrhoea death if concurrent lower respiratory infection

Real

3.51

rr_diarr_death_cryptosporidium

relative risk of diarrhoea death if caused by cryptosporidium

Real

2.14

rr_diarr_death_shigella

relative risk of diarrhoea death if caused by shigella

Real

2.8

sensitivity_severe_dehydration_visual_inspection

sensitivity of IMCI severe dehydration algorithm for dehydration >9% loss of body weight

Real

0.77

specificity_severe_dehydration_visual_inspection

specificity of IMCI severe dehydration algorithm for dehydration >9% loss of body weight

Real

0.67

prob_hospitalization_on_danger_signs

probability of hospitalisation when danger signs are detected in an initial consultation

Real

0.7

prob_WHOPlanC_cures_dehydration_if_severe_dehydration

probability that severe dehydration is cured by Treatment Plan C

Real

0.9

prob_ORS_cures_dehydration_if_severe_dehydration

probability that severe dehydration is cured by ORS

Real

0.721

prob_ORS_cures_dehydration_if_non_severe_dehydration

probability that non-severe dehydration is cured by ORS

Real

0.93

prob_antibiotic_cures_dysentery

probability that blood-in-stool is removed by the use of antibiotics

Real

0.99

number_of_days_reduced_duration_with_zinc

number of days reduced duration with zinc

Integer

1

days_between_treatment_and_cure

number of days between any treatment being given in an HSI and the cure occurring.

Integer

5

rr_severe_dehydration_due_to_rotavirus_with_R1_under1yo

relative risk of severe dehydration with rotavirus vaccine, for under 1 years old.

Real

0.63

rr_severe_dehydration_due_to_rotavirus_with_R1_over1yo

relative risk of severe dehydration with rotavirus vaccine, for those aged 1 year and older.

Real

0.35

Epi

Name

Description

Type

Value

baseline_coverage

baseline vaccination coverage (all vaccines)

Dataframe

vaccine_schedule

vaccination schedule applicable from 2018 onwards

Series

prob_facility_level_for_vaccine

The probability of going to each facility-level (0 / 1a / 1b / 2) for child having vaccines given through childhood immunisation schedule. The probabilities must sum to 1.0

List

[0, 0.8, 0.1, 0.1]

baseline_coverage

Year

BCG

DTP1

DTP3

HepB3

Hib3

MCV1

MCV2

PCV3

Pol3

RCV1

Rota

IPV1

AgeOn01Jan2010

1981

0.86

0.86

0.66

0

0

0.64

0

0

0.57

0

0

0

28

1982

0.87

0.84

0.64

0

0

0.64

0

0

0.58

0

0

0

27

1983

0.81

0.84

0.63

0

0

0.58

0

0

0.58

0

0

0

26

1984

0.74

0.8

0.58

0

0

0.5

0

0

0.56

0

0

0

25

1985

0.87

0.78

0.55

0

0

0.49

0

0

0.55

0

0

0

24

1986

0.87

0.8

0.57

0

0

0.6

0

0

0.53

0

0

0

23

1987

0.92

0.92

0.78

0

0

0.79

0

0

0.78

0

0

0

22

1988

0.9

0.94

0.82

0

0

0.82

0

0

0.72

0

0

0

21

1989

0.96

0.95

0.87

0

0

0.84

0

0

0.9

0

0

0

20

Only first 10 rows of 42 are shown.

vaccine_schedule

date_administration_days

1

42

70

98

42

70

98

42

70

Only first 10 rows of 21 are shown.

Epilepsy

Name

Description

Type

Value

init_epil_seiz_status

Proportions in each seizure status category at baseline

List

[0.974, 0.0175, 0.007, 0.0015]

init_prop_antiepileptic_seiz_stat_1

initial proportions on antiepileptic by if seizure status = 1

Real

0.15

init_prop_antiepileptic_seiz_stat_2

initial proportions on antiepileptic by if seizure status = 2

Real

0.15

init_prop_antiepileptic_seiz_stat_3

initial proportions on antiepileptic by if seizure status = 3

Real

0.2

base_3m_prob_epilepsy

base probability of epilepsy per 3 month period if age < 20

Real

0.000178

rr_epilepsy_age_ge20

relative rate of epilepsy if age over 20

Real

0.3

prop_inc_epilepsy_seiz_freq

proportion of incident epilepsy cases with frequent seizures

Real

0.1

base_prob_3m_seiz_stat_freq_infreq

base probability per 3 months of seizure status frequent if current infrequent

Real

0.05

rr_effectiveness_antiepileptics

relative rate of seizure status frequent if current infrequent if on antiepileptic

Real

3.0

base_prob_3m_seiz_stat_infreq_freq

base probability per 3 months of seizure status infrequent if current frequent

Real

0.05

base_prob_3m_seiz_stat_infreq_none

base probability per 3 months of seizure status infrequent if current nonenow

Real

0.05

base_prob_3m_seiz_stat_none_freq

base probability per 3 months of seizure status nonenow if current frequent

Real

0.05

base_prob_3m_seiz_stat_none_infreq

base probability per 3 months of seizure status nonenow if current infrequent

Real

0.05

base_prob_3m_stop_antiepileptic

base probability per 3 months of stopping antiepileptic, if nonenow seizures

Real

0.1

rr_stop_antiepileptic_seiz_infreq_or_freq

relative rate of stopping antiepileptic if infrequent or frequent seizures

Real

0.5

base_prob_3m_epi_death

base probability per 3 months of epilepsy death

Real

0.000568

daly_wt_epilepsy_severe

disability weight for severe epilepsycontrolled phase - code 860

Real

0.552

daly_wt_epilepsy_less_severe

disability weight for less severe epilepsycontrolled phase - code 861

Real

0.263

daly_wt_epilepsy_seizure_free

disability weight for less severe epilepsycontrolled phase - code 862

Real

0.049

prob_start_anti_epilep_when_seizures_detected_in_generic_first_appt

probability that someone who has had a seizure is started on anti-epileptics. This is calibrated to induce the correct proportion of persons with epilepsy currently receiving anti-epileptics.

Real

0.4

max_num_of_failed_attempts_before_defaulting

maximum number of time an HSI can be repeated if the relevant essential consumables are not available.

Integer

2

HealthSeekingBehaviour

Name

Description

Type

Value

force_any_symptom_to_lead_to_healthcareseeking

Whether every symptom [except those that declare they should not lead to any healthcare seeking] should always lead to healthcare seeking immediately.

Boolean

False

prob_non_emergency_care_seeking_by_level

The probability of going to each facility-level when non-emergency care is sought. The values in the list are the probabilities of going to facility level 0 / 1a / 1b / 2, respectively, and these values must sum to 1.0.

List

[0.14, 0.66, 0.08, 0.12]

baseline_odds_of_healthcareseeking_children

odds of health-care seeking (children: 0-14) if male, 0-5 years-old, living in a rural setting in the Northern region, and not in the wealth categories 4 or 5

Real

2.17

odds_ratio_children_sex_Female

odds ratio for health-care seeking (children) if sex is Female

Real

1.12

odds_ratio_children_age_5to14

odds ratio for health-care seeking (children) if aged 5-14

Real

0.5

odds_ratio_children_setting_urban

odds ratio for health-care seeking (children) if setting is Urban

Real

1.75

odds_ratio_children_region_Central

odds ratio for health-care seeking (children) if region is Central

Real

0.43

odds_ratio_children_region_Southern

odds ratio for health-care seeking (children) if region is Southern

Real

0.56

odds_ratio_children_wealth_higher

odds ratio for health-care seeking (children) if wealth is in categories 4 or 5

Real

1.9

baseline_odds_of_healthcareseeking_adults

odds of health-care seeking (adults: 15+) if male, 15-34 year-olds, living in a rural setting in the Northern region, and not in the wealth categories 4 or 5.

Real

1.27

odds_ratio_adults_sex_Female

odds ratio for health-care seeking (adults) if sex is Female

Real

1.28

odds_ratio_adults_age_35to59

odds ratio for health-care seeking (adults) if aged 35-59

Real

0.93

odds_ratio_adults_age_60plus

odds ratio for health-care seeking (adults) if aged 60+

Real

0.94

odds_ratio_adults_setting_urban

odds ratio for health-care seeking (adults) if setting is Urban

Real

1.67

odds_ratio_adults_region_Central

odds ratio for health-care seeking (adults) if region is Central

Real

0.6

odds_ratio_adults_region_Southern

odds ratio for health-care seeking (adults) if region is Southern

Real

0.68

odds_ratio_adults_wealth_higher

odds ratio for health-care seeking (adults) if wealth is in categories 4 or 5

Real

1.56

max_days_delay_to_generic_HSI_after_symptoms

Maximum days delay between symptom onset and firstgeneric HSI. Actual delay is sample between 0 and this value.

Integer

4

HealthSystem

Name

Description

Type

Value

Master_Facilities_List

Listing of all health facilities.

Dataframe

Officer_Types_Table

The names of the types of health workers (“officers”)

Dataframe

Appt_Types_Table

The names of the type of appointments with the health system

Dataframe

Appt_Offered_By_Facility_Level

Table indicating whether or not each appointment is offered at each facility level.

Dataframe

Appt_Time_Table

The time taken for each appointment, according to officer and facility type.

Dataframe

Daily_Capabilities_actual

The capabilities (minutes of time available of each type of officer in each facility) based on the _estimated current_ number and distribution of staff estimated.

Dataframe

Daily_Capabilities_funded

The capabilities (minutes of time available of each type of officer in each facility) based on the _potential_ number and distribution of staff estimated (i.e. those positions that can be funded).

Dataframe

Daily_Capabilities_funded_plus

The capabilities (minutes of time available of each type of officer in each facility) based on the _potential_ number and distribution of staff estimated, with adjustments to permit each appointment type that should be run at facility level to do so in every district.

Dataframe

use_funded_or_actual_staffing

If actual, then use the numbers and distribution of staff estimated to be available currently; If funded, then use the numbers and distribution of staff that are potentially available. If funded_plus, then use a dataset in which the allocation of staff to facilities is tweaked so as to allow each appointment type to run at each facility_level in each district for which it is defined. N.B. This parameter is over-ridden if an argument is provided to the module initialiser.

String

actual

item_and_package_code_lookups

Data imported from the OneHealth Tool on consumable items, packages and costs.

Dataframe

consumables_item_designations

Look-up table for the designations of consumables (whether diagnostic, medicine, or other

Dataframe

availability_estimates

Estimated availability of consumables in the LMIS dataset.

Dataframe

cons_availability

Availability of consumables. If ‘default’ then use the availability specified in the ResourceFile; if ‘none’, then let no consumable be ever be available; if ‘all’, then all consumables are always available. When using ‘all’ or ‘none’, requests for consumables are not logged. NB. This parameter is over-riddenif an argument is provided to the module initialiser.Note that other options are also available: see the Consumables class.

String

default

BedCapacity

Data on the number of beds available of each type by facility_id

Dataframe

beds_availability

Availability of beds. If ‘default’ then use the availability specified in the ResourceFile; if ‘none’, then let no beds be ever be available; if ‘all’, then all beds are always available. NB. This parameter is over-ridden if an argument is provided to the module initialiser.

String

default

EquipmentCatalogue

Data on equipment items and packages.

Dataframe

equipment_availability_estimates

Data on the availability of equipment items and packages.

Dataframe

equip_availability

What to assume about the availability of equipment. If ‘default’ then use the availability specified in the ResourceFile; if ‘none’, then let no equipment ever be available; if ‘all’, then all equipment is always available. NB. This parameter is over-ridden if an argument is provided to the module initialiser.

String

all

equip_availability_postSwitch

What to assume about the availability of equipment after the switch (see year_equip_availability_switch). The options for this are the same as equip_availability.

String

default

year_equip_availability_switch

Year in which the assumption for equip_availability changes (The change happens on 1st January of that year.)

Integer

2100

Service_Availability

List of services to be available. NB. This parameter is over-ridden if an argument is provided to the module initialiser.

List

[‘*’]

policy_name

Name of priority policy adopted

String

Naive

year_mode_switch

Year in which mode switch is enforced

Integer

2100

scale_to_effective_capabilities

In year in which mode switch takes place, will rescale available capabilities to match thosethat were effectively used (on average) in the past year if this is set to True. This way,we can approximate overtime and rushing of appts even in mode 2.

Boolean

False

year_cons_availability_switch

Year in which consumable availability switch is enforced. The change happenson 1st January of that year.)

Integer

2100

year_use_funded_or_actual_staffing_switch

Year in which switch for use_funded_or_actual_staffing is enforced. (The change happenson 1st January of that year.)

Integer

2100

priority_rank

Data on the priority ranking of each of the Treatment_IDs to be adopted by the queueing system under different policies, where the lower the number the higher the priority, and on which categories of individuals classify for fast-tracking for specific treatments

Dictionary

HR_scaling_by_level_and_officer_type_table

Factors by which capabilities of medical officer types at different levels will bescaled at the start of the year specified by year_HR_scaling_by_level_and_officer_type. Thisserves to simulate a number of effects (e.g. absenteeism, boosting capabilities of specific medical cadres, etc). This is the imported from an Excel workbook: keys are the worksheet names and values are the worksheets in the format of pd.DataFrames. Additional scenarios can be added by adding worksheets to this workbook: the value of HR_scaling_by_level_and_officer_type_mode indicates which sheet is used.

Dictionary

year_HR_scaling_by_level_and_officer_type

Year in which one-off constant HR scaling will take place. (The change happenson 1st January of that year.)

Integer

2100

HR_scaling_by_level_and_officer_type_mode

Mode of HR scaling considered at the start of the simulation. This corresponds to the nameof the worksheet in ResourceFile_HR_scaling_by_level_and_officer_type.xlsx that should be used. Options are: default (capabilities are scaled by a constaint factor of 1); data (factors informed by survey data); and, custom (user can freely set these factors as parameters in the analysis).

String

default

HR_scaling_by_district_table

Factors by which daily capabilities in different districts will bescaled at the start of the year specified by year_HR_scaling_by_district to simulate(e.g., through catastrophic event disrupting delivery of services in particular district(s)).This is the import of an Excel workbook: keys are the worksheet names and values are the worksheets in the format of pd.DataFrames. Additional scenarios can be added by adding worksheets to this workbook: the value of HR_scaling_by_district_mode indicates whichsheet is used.

Dictionary

year_HR_scaling_by_district

Year in which scaling of daily capabilities by district will take place. (The change happenson 1st January of that year.)

Integer

2100

HR_scaling_by_district_mode

Mode of scaling of daily capabilities by district. This corresponds to the name of the worksheet in the file ResourceFile_HR_scaling_by_district.xlsx.

String

default

yearly_HR_scaling

Factors by which HR capabilities are scaled. Each sheet specifies a ‘mode’ for dynamic HR scaling. The mode to use is determined by the parameter yearly_HR_scaling_mode. Each sheet must have the same format, including the same column headers. On each sheet, the first row (for 2010, when the simulation starts) specifies the initial configuration: dynamic_HR_scaling_factor (float) is the factor by which all human resoucres capabilities and multiplied; scale_HR_by_popsize (bool) specifies whether the capabilities should (also) grow by the factor by which the population has grown in the last year. Each subsequent row specifies a year where there should be a CHANGE in the configuration. If there are no further rows, then there is no change. But, for example, an additional row of the form `2015, 1.05, TRUE` would mean that on 1st January of 2015, 2016, 2017, ….(and the rest of the simulation), the capabilities would increase by the product of 1.05 and by the ratio of the population size to that in the year previous.

Dictionary

yearly_HR_scaling_mode

Specifies which of the policies in yearly_HR_scaling should be adopted. This corresponds toa worksheet of the file ResourceFile_dynamic_HR_scaling.xlsx.

String

no_scaling

tclose_overwrite

Decide whether to overwrite tclose variables assigned by disease modules

Integer

0

tclose_days_offset_overwrite

Offset in days from topen at which tclose will be set by the healthsystem for all HSIsif tclose_overwrite is set to True.

Integer

7

mode_appt_constraints

Integer code in {0, 1, 2} determining mode of constraints with regards to officer numbers and time - 0: no constraints, all HSI events run with no squeeze factor, 1: elastic constraints, all HSI events run with squeeze factor, 2: hard constraints, only HSI events with no squeeze factor run. N.B. This parameter is over-ridden if an argument is provided to the module initialiser.

Integer

1

mode_appt_constraints_postSwitch

Mode considered after a mode switch in year_mode_switch.

Integer

1

cons_availability_postSwitch

Consumables availability after switch in year_cons_availability_switch. Acceptable valuesare the same as those for Parameter cons_availability.

String

default

use_funded_or_actual_staffing_postSwitch

Staffing availability after switch in year_use_funded_or_actual_staffing_switch. Acceptable values are the same as those for Parameter use_funded_or_actual_staffing.

String

funded_plus

Master_Facilities_List

District

Facility_Level

Region

Facility_ID

Facility_Name

Balaka

1a

Southern

1

Facility_Level_1a_Balaka

Balaka

1b

Southern

2

Facility_Level_1b_Balaka

Balaka

2

Southern

3

Facility_Level_2_Balaka

Blantyre

0

Southern

4

Facility_Level_0_Blantyre

Blantyre

1a

Southern

5

Facility_Level_1a_Blantyre

Blantyre

1b

Southern

6

Facility_Level_1b_Blantyre

Blantyre

2

Southern

7

Facility_Level_2_Blantyre

Blantyre City

0

Southern

8

Facility_Level_0_Blantyre City

Blantyre City

1a

Southern

9

Facility_Level_1a_Blantyre City

Only first 10 rows of 133 are shown.

Officer_Types_Table

Officer_Type

Officer_Type_Code

Officer_Category

Clinical Officer / Technician

M02

Clinical

Med. Assistant

M03

Clinical

Nurse Officer

N01

Nursing_and_Midwifery

Nurse Midwife Technician

N02

Nursing_and_Midwifery

Pharmacist

P01

Pharmacy

Pharm Technician

P02

Pharmacy

Pharm Assistant

P03

Pharmacy

Lab Officer

L01

Laboratory

Lab Technician

L02

Laboratory

Only first 10 rows of 21 are shown.

Appt_Types_Table

Appt_Type_Code

Appt_Cat

Appt_Type

IPAdmission

GENERAL_INPATIENT_AND_OUTPATIENT_CARE

Inpatient Admissions and Discharge Process

Under5OPD

GENERAL_INPATIENT_AND_OUTPATIENT_CARE

Under 5 Outpatient Visit

Over5OPD

GENERAL_INPATIENT_AND_OUTPATIENT_CARE

Over 5 Outpatient visit

NormalDelivery

RMNCH

Normal Deliveries

CompDelivery

RMNCH

Complicated Deliveries

Csection

RMNCH

Caesarean Sections

FamPlan

RMNCH

Family Planning

AntenatalFirst

RMNCH

Antenatal Care - First Visit

ANCSubsequent

RMNCH

Antenatal Care - Followup Visit

Only first 10 rows of 50 are shown.

Appt_Offered_By_Facility_Level

Appt_Type_Code

Facility_Level_0

Facility_Level_1a

Facility_Level_1b

Facility_Level_2

Facility_Level_3

Facility_Level_4

Facility_Level_5

IPAdmission

False

True

True

True

True

False

False

Under5OPD

False

True

True

True

True

False

False

Over5OPD

False

True

True

True

True

False

False

NormalDelivery

False

True

True

True

True

False

False

CompDelivery

False

True

True

True

True

False

False

Csection

False

True

True

True

True

False

False

FamPlan

False

True

True

True

False

False

False

AntenatalFirst

False

True

True

True

True

False

False

ANCSubsequent

False

True

True

True

True

False

False

Only first 10 rows of 50 are shown.

Appt_Time_Table

Appt_Type_Code

Facility_Level

Officer_Category

Time_Taken_Mins

ANCSubsequent

2

Nursing_and_Midwifery

18

ANCSubsequent

2

Pharmacy

1

ANCSubsequent

3

Clinical

3

ANCSubsequent

3

Nursing_and_Midwifery

15

ANCSubsequent

3

Pharmacy

5

ANCSubsequent

1a

Clinical

1

ANCSubsequent

1a

Nursing_and_Midwifery

11

ANCSubsequent

1a

Pharmacy

0.4

ANCSubsequent

1b

Clinical

2

Only first 10 rows of 345 are shown.

Daily_Capabilities_actual

Facility_ID

Facility_Name

Facility_Level

District

Region

Officer_Category

Total_Mins_Per_Day

Staff_Count

0

Facility_Level_0_Balaka

0

Balaka

Southern

DCSA

17362.5

311

0

Facility_Level_0_Balaka

0

Balaka

Southern

Dental

0

0

0

Facility_Level_0_Balaka

0

Balaka

Southern

Laboratory

0

0

0

Facility_Level_0_Balaka

0

Balaka

Southern

Mental

0

0

0

Facility_Level_0_Balaka

0

Balaka

Southern

Nursing_and_Midwifery

0

0

0

Facility_Level_0_Balaka

0

Balaka

Southern

Nutrition

0

0

0

Facility_Level_0_Balaka

0

Balaka

Southern

Pharmacy

0

0

0

Facility_Level_0_Balaka

0

Balaka

Southern

Radiography

0

0

1

Facility_Level_1a_Balaka

1a

Balaka

Southern

Clinical

7764.57

35.9682

Only first 10 rows of 1197 are shown.

Daily_Capabilities_funded

Facility_ID

Facility_Name

Facility_Level

District

Region

Officer_Category

Total_Mins_Per_Day

Staff_Count

0

Facility_Level_0_Balaka

0

Balaka

Southern

DCSA

13957

250

0

Facility_Level_0_Balaka

0

Balaka

Southern

Dental

0

0

0

Facility_Level_0_Balaka

0

Balaka

Southern

Laboratory

0

0

0

Facility_Level_0_Balaka

0

Balaka

Southern

Mental

0

0

0

Facility_Level_0_Balaka

0

Balaka

Southern

Nursing_and_Midwifery

0

0

0

Facility_Level_0_Balaka

0

Balaka

Southern

Nutrition

0

0

0

Facility_Level_0_Balaka

0

Balaka

Southern

Pharmacy

0

0

0

Facility_Level_0_Balaka

0

Balaka

Southern

Radiography

0

0

1

Facility_Level_1a_Balaka

1a

Balaka

Southern

Clinical

9786.98

47.0287

Only first 10 rows of 1197 are shown.

Daily_Capabilities_funded_plus

Facility_ID

Facility_Name

Facility_Level

District

Region

Officer_Category

Total_Mins_Per_Day

Staff_Count

1

Facility_Level_1a_Balaka

1a

Balaka

Southern

Clinical

9786.98

47.0287

1

Facility_Level_1a_Balaka

1a

Balaka

Southern

Dental

2327.32

11.3933

1

Facility_Level_1a_Balaka

1a

Balaka

Southern

Laboratory

5012.02

24.9123

1

Facility_Level_1a_Balaka

1a

Balaka

Southern

Nursing_and_Midwifery

31874.9

150.48

1

Facility_Level_1a_Balaka

1a

Balaka

Southern

Nutrition

110.791

0.542373

1

Facility_Level_1a_Balaka

1a

Balaka

Southern

Pharmacy

4132.1

20.6361

2

Facility_Level_1b_Balaka

1b

Balaka

Southern

Clinical

6470

31.8781

2

Facility_Level_1b_Balaka

1b

Balaka

Southern

Dental

719.736

3.52345

2

Facility_Level_1b_Balaka

1b

Balaka

Southern

Laboratory

1340.35

5.95697

Only first 10 rows of 733 are shown.

item_and_package_code_lookups

Intervention_Cat

Intervention_Pkg

Intervention_Pkg_Code

Items

Item_Code

Expected_Units_Per_Case

Unit_Cost

Maternal/Newborn and Reproductive Health

Pill

0

Levonorgestrel 0.15 mg + Ethinyl estradiol 30 mcg (Microgynon), cycle

1

7.5

53.3501

Maternal/Newborn and Reproductive Health

Male condom

1

Condom, male

2

120

20.9702

Maternal/Newborn and Reproductive Health

Injectable

2

Depot-Medroxyprogesterone Acetate 150 mg - 3 monthly

3

4

50.9439

Maternal/Newborn and Reproductive Health

Injectable

2

Gloves, exam, latex, disposable, pair

4

4

31.9087

Maternal/Newborn and Reproductive Health

Injectable

2

Povidone iodine, solution, 10 %, 5 ml per injection

5

4

2.00634

Maternal/Newborn and Reproductive Health

Injectable

2

Syringe, Autodisable SoloShot IX

6

4

5.4264

Maternal/Newborn and Reproductive Health

IUD

3

Gloves, exam, latex, disposable, pair

4

3

31.9087

Maternal/Newborn and Reproductive Health

IUD

3

IUD, Copper T-380A

7

1

19.3922

Maternal/Newborn and Reproductive Health

Implant

4

Gloves, exam, latex, disposable, pair

4

2

31.9087

Only first 10 rows of 2444 are shown.

consumables_item_designations

is_diagnostic

is_medicine

is_other

is_vital

is_drug_or_vaccine

0

0

1

1

0

0

1

0

1

1

0

0

1

1

0

0

1

0

1

0

0

0

1

1

0

0

1

0

1

0

0

1

0

0

1

0

0

1

1

0

0

0

1

1

0

Only first 10 rows of 2016 are shown.

availability_estimates

Facility_ID

month

item_code

available_prop

0

1

1

0.3825

0

1

2

0.555

0

1

3

0.33875

0

1

5

0.145161

0

1

6

0.609167

0

1

7

0.4

0

1

8

0

0

1

11

0.25

0

1

12

0.357143

Only first 10 rows of 307296 are shown.

BedCapacity

Facility_ID

maternity_bed

delivery_bed

general_bed

non_bed_space

1

134

29

14

1000

2

49

6

57

1000

3

35

4

54

1000

4

0

0

0

0

5

168

32

50

1000

6

61

7

195

1000

7

44

4

184

1000

8

0

0

0

0

9

168

32

50

1000

Only first 10 rows of 133 are shown.

EquipmentCatalogue

Item_Description

Item_Code

Pkg_Name

Source_Equip_Item

Alternative item names

Weighing scale

1

ANC

Malawi HSSPIII Equipment Costing 2023

‘Salter weighing scale’, ‘Waeighing Scale’

Autoclave

2

nan

Malawi HSSPIII Equipment Costing 2023

‘High pressure cooker sterilizer, complete with stove’, ‘Sterilization drums, medium’, ‘Sterilization drum’, ‘Sterilization buckets’, ‘Sterilization buckets (decontamination buckets)’, ‘Sterilization Buckets’, ‘Decontamination drums’, ‘Dressing drum medium’, ‘Dressing drum large’, ‘Dressing drum small’

Refrigerator

3

nan

Malawi HSSPIII Equipment Costing 2023

‘Vaccine refrigerator (solar)’, ‘Vaccine Refrigerator’

Cold box

4

nan

Malawi HSSPIII Equipment Costing 2023

‘Cold Chain Box-large’, ‘Cold Chain Box-medium’

Vaccine Carriers

5

nan

Malawi HSSPIII Equipment Costing 2023

nan

Blood pressure machine

6

Minor Surgery, Major Surgery, ICU

Malawi HSSPIII Equipment Costing 2023

nan

Thermometer

7

nan

Malawi HSSPIII Equipment Costing 2023

‘Thermometers, digital’

Push bike for mobility

8

nan

Malawi HSSPIII Equipment Costing 2023

nan

Desk

9

nan

Malawi HSSPIII Equipment Costing 2023

‘Office desk’

Only first 10 rows of 404 are shown.

equipment_availability_estimates

Facility_ID

Item_Code

Pr_Available

0

1

0.75

0

2

1

0

3

1

0

4

0.226281

0

5

0.226281

0

6

0.25

0

7

0.75

0

8

0.226281

0

9

0.226281

Only first 10 rows of 53732 are shown.

priority_rank

Default

Treatment

Priority

FT_if_5orUnder

FT_if_pregnant

FT_if_tbdiagnosed

FT_if_Hivdiagnosed

FirstAttendance_SpuriousEmergencyCare

0

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Outpatient

0

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Inpatient

0

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Inpatient_Followup

0

-1

-1

-1

-1

BladderCancer_Investigation

0

-1

-1

-1

-1

BladderCancer_PalliativeCare

0

-1

-1

-1

-1

BladderCancer_Treatment

0

-1

-1

-1

-1

BreastCancer_Investigation

0

-1

-1

-1

-1

BreastCancer_PalliativeCare

0

-1

-1

-1

-1

Only first 10 rows of 87 are shown.

Test

Treatment

Priority

FT_if_5orUnder

FT_if_pregnant

FT_if_tbdiagnosed

FT_if_Hivdiagnosed

FirstAttendance_SpuriousEmergencyCare

0

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Outpatient

0

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Inpatient

0

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Inpatient_Followup

0

-1

-1

-1

-1

BladderCancer_Investigation

0

-1

-1

-1

-1

BladderCancer_PalliativeCare

0

-1

-1

-1

-1

BladderCancer_Treatment

0

-1

-1

-1

-1

BreastCancer_Investigation

0

-1

-1

-1

-1

BreastCancer_PalliativeCare

0

-1

-1

-1

-1

Only first 10 rows of 87 are shown.

Naive

Treatment

Priority

FT_if_5orUnder

FT_if_pregnant

FT_if_tbdiagnosed

FT_if_Hivdiagnosed

FirstAttendance_SpuriousEmergencyCare

1

0

-1

-1

-1

Alri_Pneumonia_Treatment_Outpatient

2

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Inpatient

2

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Inpatient_Followup

2

-1

-1

-1

-1

BladderCancer_Investigation

2

-1

-1

-1

-1

BladderCancer_PalliativeCare

2

-1

-1

-1

-1

BladderCancer_Treatment

2

-1

-1

-1

-1

BreastCancer_Investigation

2

-1

-1

-1

-1

BreastCancer_PalliativeCare

2

-1

-1

-1

-1

Only first 10 rows of 87 are shown.

Test Mode 1

Treatment

Priority

FT_if_5orUnder

FT_if_pregnant

FT_if_tbdiagnosed

FT_if_Hivdiagnosed

FirstAttendance_SpuriousEmergencyCare

4

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Outpatient

0

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Inpatient

4

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Inpatient_Followup

0

-1

-1

-1

-1

BladderCancer_Investigation

4

-1

-1

-1

-1

BladderCancer_PalliativeCare

0

-1

-1

-1

-1

BladderCancer_Treatment

4

-1

-1

-1

-1

BreastCancer_Investigation

0

-1

-1

-1

-1

BreastCancer_PalliativeCare

4

-1

-1

-1

-1

Only first 10 rows of 87 are shown.

ClinicallyVulnerable

Treatment

Priority

FT_if_5orUnder

FT_if_pregnant

FT_if_tbdiagnosed

FT_if_Hivdiagnosed

FirstAttendance_SpuriousEmergencyCare

1

0

-1

-1

-1

Alri_Pneumonia_Treatment_Outpatient

3

2

2

2

2

Alri_Pneumonia_Treatment_Inpatient

3

2

2

2

2

Alri_Pneumonia_Treatment_Inpatient_Followup

3

2

2

2

2

BladderCancer_Investigation

3

2

2

2

2

BladderCancer_PalliativeCare

3

2

2

2

2

BladderCancer_Treatment

3

2

2

2

2

BreastCancer_Investigation

3

2

2

2

2

BreastCancer_PalliativeCare

3

2

2

2

2

Only first 10 rows of 87 are shown.

VerticalProgrammes

Treatment

Priority

FT_if_5orUnder

FT_if_pregnant

FT_if_tbdiagnosed

FT_if_Hivdiagnosed

FirstAttendance_SpuriousEmergencyCare

1

0

-1

-1

-1

Alri_Pneumonia_Treatment_Outpatient

3

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Inpatient

3

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Inpatient_Followup

3

-1

-1

-1

-1

BladderCancer_Investigation

3

-1

-1

-1

-1

BladderCancer_PalliativeCare

3

-1

-1

-1

-1

BladderCancer_Treatment

3

-1

-1

-1

-1

BreastCancer_Investigation

3

-1

-1

-1

-1

BreastCancer_PalliativeCare

3

-1

-1

-1

-1

Only first 10 rows of 87 are shown.

RMNCH

Treatment

Priority

FT_if_5orUnder

FT_if_pregnant

FT_if_tbdiagnosed

FT_if_Hivdiagnosed

FirstAttendance_SpuriousEmergencyCare

1

0

-1

-1

-1

Alri_Pneumonia_Treatment_Outpatient

5

3

-1

-1

-1

Alri_Pneumonia_Treatment_Inpatient

5

3

-1

-1

-1

Alri_Pneumonia_Treatment_Inpatient_Followup

5

3

-1

-1

-1

BladderCancer_Investigation

5

-1

-1

-1

-1

BladderCancer_PalliativeCare

5

-1

-1

-1

-1

BladderCancer_Treatment

5

-1

-1

-1

-1

BreastCancer_Investigation

5

-1

-1

-1

-1

BreastCancer_PalliativeCare

5

-1

-1

-1

-1

Only first 10 rows of 87 are shown.

EHP_III

Treatment

Priority

FT_if_5orUnder

FT_if_pregnant

FT_if_tbdiagnosed

FT_if_Hivdiagnosed

FirstAttendance_SpuriousEmergencyCare

1

0

-1

-1

-1

Alri_Pneumonia_Treatment_Outpatient

2

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Inpatient

2

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Inpatient_Followup

2

-1

-1

-1

-1

BladderCancer_Investigation

4

-1

-1

-1

-1

BladderCancer_PalliativeCare

4

-1

-1

-1

-1

BladderCancer_Treatment

4

-1

-1

-1

-1

BreastCancer_Investigation

4

-1

-1

-1

-1

BreastCancer_PalliativeCare

4

-1

-1

-1

-1

Only first 10 rows of 87 are shown.

LCOA_EHP

Treatment

Priority

FT_if_5orUnder

FT_if_pregnant

FT_if_tbdiagnosed

FT_if_Hivdiagnosed

FirstAttendance_SpuriousEmergencyCare

1

0

-1

-1

-1

Alri_Pneumonia_Treatment_Outpatient

2

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Inpatient

3

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Inpatient_Followup

3

-1

-1

-1

-1

BladderCancer_Investigation

4

-1

-1

-1

-1

BladderCancer_PalliativeCare

4

-1

-1

-1

-1

BladderCancer_Treatment

4

-1

-1

-1

-1

BreastCancer_Investigation

4

-1

-1

-1

-1

BreastCancer_PalliativeCare

4

-1

-1

-1

-1

Only first 10 rows of 87 are shown.

CVD

Treatment

Priority

FT_if_5orUnder

FT_if_pregnant

FT_if_tbdiagnosed

FT_if_Hivdiagnosed

FirstAttendance_SpuriousEmergencyCare

1

0

-1

-1

-1

Alri_Pneumonia_Treatment_Outpatient

3

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Inpatient

3

-1

-1

-1

-1

Alri_Pneumonia_Treatment_Inpatient_Followup

3

-1

-1

-1

-1

BladderCancer_Investigation

3

-1

-1

-1

-1

BladderCancer_PalliativeCare

3

-1

-1

-1

-1

BladderCancer_Treatment

3

-1

-1

-1

-1

BreastCancer_Investigation

3

-1

-1

-1

-1

BreastCancer_PalliativeCare

3

-1

-1

-1

-1

Only first 10 rows of 87 are shown.

HR_scaling_by_level_and_officer_type_table

default

Officer_Category

L0_factor

L1a_factor

L1b_factor

L2_factor

L3_factor

L4_factor

L5_factor

Clinical

1

1

1

1

1

1

1

DCSA

1

1

1

1

1

1

1

Dental

1

1

1

1

1

1

1

Laboratory

1

1

1

1

1

1

1

Mental

1

1

1

1

1

1

1

Nursing_and_Midwifery

1

1

1

1

1

1

1

Nutrition

1

1

1

1

1

1

1

Pharmacy

1

1

1

1

1

1

1

Radiography

1

1

1

1

1

1

1

data

Officer_Category

L0_factor

L1a_factor

L1b_factor

L2_factor

L3_factor

L4_factor

L5_factor

Clinical

1

0.795927

0.836783

1.00678

1

1

1

DCSA

2.13327

1

1

1

1

1

1

Dental

1

1.46777

1.46777

1.46777

1

1

1

Laboratory

1

1.0149

0.997807

1.14721

1

1

1

Mental

1

1

1

1

1

1

1

Nursing_and_Midwifery

1

0.605695

0.615689

0.799333

1

1

1

Nutrition

1

1

1

1

1

1

1

Pharmacy

1

1.02347

1.06089

1.30115

1

1

1

Radiography

1

1

0.275236

0.277971

1

1

1

custom

Officer_Category

L0_factor

L1a_factor

L1b_factor

L2_factor

L3_factor

L4_factor

L5_factor

Clinical

0.5

0.5

0.5

0.5

0.5

0.5

0.5

DCSA

0.5

0.5

0.5

0.5

0.5

0.5

0.5

Dental

0.5

0.5

0.5

0.5

0.5

0.5

0.5

Laboratory

0.5

0.5

0.5

0.5

0.5

0.5

0.5

Mental

0.5

0.5

0.5

0.5

0.5

0.5

0.5

Nursing_and_Midwifery

0.5

0.5

0.5

0.5

0.5

0.5

0.5

Nutrition

0.5

0.5

0.5

0.5

0.5

0.5

0.5

Pharmacy

0.5

0.5

0.5

0.5

0.5

0.5

0.5

Radiography

0.5

0.5

0.5

0.5

0.5

0.5

0.5

x2_fac0&1

Officer_Category

L0_factor

L1a_factor

L1b_factor

L2_factor

L3_factor

L4_factor

L5_factor

Clinical

2

2

2

1

1

1

1

DCSA

2

2

2

1

1

1

1

Dental

2

2

2

1

1

1

1

Laboratory

2

2

2

1

1

1

1

Mental

2

2

2

1

1

1

1

Nursing_and_Midwifery

2

2

2

1

1

1

1

Nutrition

2

2

2

1

1

1

1

Pharmacy

2

2

2

1

1

1

1

Radiography

2

2

2

1

1

1

1

HR_scaling_by_district_table

default

District

Factor

Blantyre

1

Blantyre City

1

Chikwawa

1

Chiradzulu

1

Chitipa

1

Dedza

1

Dowa

1

Karonga

1

Kasungu

1

Only first 10 rows of 32 are shown.

yearly_HR_scaling

no_scaling

year

dynamic_HR_scaling_factor

scale_HR_by_popsize

2010

1

False

scaling_by_population_growth

year

dynamic_HR_scaling_factor

scale_HR_by_popsize

2010

1

False

2019

1

True

GDP_growth

year

dynamic_HR_scaling_factor

scale_HR_by_popsize

2010

1

False

2019

1.042

False

GDP_growth_fHE_case1

year

dynamic_HR_scaling_factor

scale_HR_by_popsize

2010

1

False

2019

1.01074

False

GDP_growth_fHE_case2

year

dynamic_HR_scaling_factor

scale_HR_by_popsize

2010

1

False

2019

1.02116

False

GDP_growth_fHE_case3

year

dynamic_HR_scaling_factor

scale_HR_by_popsize

2010

1

False

2019

1.02637

False

GDP_growth_fHE_case4

year

dynamic_HR_scaling_factor

scale_HR_by_popsize

2010

1

False

2019

1.05763

False

GDP_growth_fHE_case5

year

dynamic_HR_scaling_factor

scale_HR_by_popsize

2010

1

False

2019

1.06284

False

GDP_growth_fHE_case6

year

dynamic_HR_scaling_factor

scale_HR_by_popsize

2010

1

False

2019

1.07326

False

GDP_growth_FL_case1_const_tot_i

year

dynamic_HR_scaling_factor

scale_HR_by_popsize

2010

1

False

2018

1.1

False

2019

1.042

False

2032

0.861157

False

2033

1.042

False

GDP_growth_FL_case2_const_tot_i

year

dynamic_HR_scaling_factor

scale_HR_by_popsize

2010

1

False

2018

1.3

False

2019

1.042

False

2031

0.616568

False

2032

1.042

False

GDP_growth_FL_case1_vary_tot_in

year

dynamic_HR_scaling_factor

scale_HR_by_popsize

2010

1

False

2018

1.1

False

2019

1.042

False

GDP_growth_FL_case2_vary_tot_in

year

dynamic_HR_scaling_factor

scale_HR_by_popsize

2010

1

False

2018

1.3

False

2019

1.042

False

Hiv

Name

Description

Type

Value

time_inf

prob of time since infection for baseline adult pop

Dataframe

art_coverage

coverage of ART at baseline

Dataframe

treatment_cascade

spectrum estimates of treatment cascade

Dataframe

beta

Transmission rate

Real

0.14379

unaids_prevalence_adjustment_factor

adjustment for baseline age-specific prevalence values to give correct population prevalence

Real

1.1

prob_mtct_untreated

Probability of mother to child transmission

Real

0.22

prob_mtct_treated

Probability of mother to child transmission, mother on ART

Real

0.0

prob_mtct_incident_preg

Probability of mother to child transmission, mother infected during pregnancy

Real

0.3

monthly_prob_mtct_bf_untreated

Probability of mother to child transmission during breastfeeding

Real

0.01

monthly_prob_mtct_bf_treated

Probability of mother to child transmission, mother infected during breastfeeding

Real

0.0

rr_fsw

Relative risk of HIV with female sex work

Real

25.0

rr_circumcision

Relative risk of HIV with circumcision

Real

0.4

rr_rural

Relative risk of HIV in rural location

Real

0.52

rr_windex_poorer

Relative risk of HIV with wealth level poorer

Real

0.96

rr_windex_middle

Relative risk of HIV with wealth level middle

Real

1.18

rr_windex_richer

Relative risk of HIV with wealth level richer

Real

1.19

rr_windex_richest

Relative risk of HIV with wealth level richest

Real

1.56

rr_sex_f

Relative risk of HIV if female

Real

1.43

rr_edlevel_primary

Relative risk of HIV with primary education

Real

1.18

rr_edlevel_secondary

Relative risk of HIV with secondary education

Real

1.15

rr_edlevel_higher

Relative risk of HIV with higher education

Real

1.0

rr_schisto

Relative risk of HIV with high intensity S. haematobium infection

Real

2.3

rr_behaviour_change

Relative risk of HIV with behaviour modification

Real

0.75

proportion_reduction_in_risk_of_hiv_aq_if_on_prep

Proportion reduction in risk of HIV acquisition if on PrEP. 0 for no efficacy; 1.0 for perfect efficacy.

Real

0.9

mean_months_between_aids_and_death

Mean number of months (distributed exponentially) for the time between AIDS and AIDS Death

Real

18.0

mean_months_between_aids_and_death_infant

Mean number of months for the time between AIDS and AIDS Death for infants

Real

6.0

infection_to_death_weibull_shape_1519

Shape parameter for Weibull describing time between infection and death for 15-19 yo (units: years)

Real

2.0

infection_to_death_weibull_shape_2024

Shape parameter for Weibull describing time between infection and death for 20-24 yo (units: years)

Real

2.0

infection_to_death_weibull_shape_2529

Shape parameter for Weibull describing time between infection and death for 25-29 yo (units: years)

Real

2.0

infection_to_death_weibull_shape_3034

Shape parameter for Weibull describing time between infection and death for 30-34 yo (units: years)

Real

2.0

infection_to_death_weibull_shape_3539

Shape parameter for Weibull describing time between infection and death for 35-39 yo (units: years)

Real

2.0

infection_to_death_weibull_shape_4044

Shape parameter for Weibull describing time between infection and death for 40-44 yo (units: years)

Real

2.0

infection_to_death_weibull_shape_4549

Shape parameter for Weibull describing time between infection and death for 45-49 yo (units: years)

Real

2.0

infection_to_death_weibull_scale_1519

Scale parameter for Weibull describing time between infection and death for 15-19 yo (units: years)

Real

16.0

infection_to_death_weibull_scale_2024

Scale parameter for Weibull describing time between infection and death for 20-24 yo (units: years)

Real

15.4

infection_to_death_weibull_scale_2529

Scale parameter for Weibull describing time between infection and death for 25-29 yo (units: years)

Real

14.1

infection_to_death_weibull_scale_3034

Scale parameter for Weibull describing time between infection and death for 30-34 yo (units: years)

Real

12.1

infection_to_death_weibull_scale_3539

Scale parameter for Weibull describing time between infection and death for 35-39 yo (units: years)

Real

11.0

infection_to_death_weibull_scale_4044

Scale parameter for Weibull describing time between infection and death for 40-44 yo (units: years)

Real

10.01

infection_to_death_weibull_scale_4549

Scale parameter for Weibull describing time between infection and death for 45-49 yo (units: years)

Real

7.9

art_default_to_aids_mean_years

Mean years between when a person (any change) stops being on treatment to when AIDS is onset (if the absence of resuming treatment).

Real

5.0

prop_delayed_aids_onset

Proportion of PLHIV that will have delayed AIDS onset to compensate for AIDS-TB

Real

0.3

mean_survival_for_infants_infected_prior_to_birth

Exponential rate parameter for mortality in infants who are infected before birth

Real

1.08

infection_to_death_infant_infection_after_birth_weibull_scale

Weibull scale parameter for mortality in infants who are infected after birth

Real

16.0

infection_to_death_infant_infection_after_birth_weibull_shape

Weibull shape parameter for mortality in infants who are infected after birth

Real

2.7

hiv_testing_rates

annual rates of testing for children and adults

Dataframe

rr_test_hiv_positive

relative likelihood of having HIV test for people with HIV

Real

1.1

hiv_testing_rate_adjustment

adjustment to current testing rates to account for multiple routes into HIV testing

Real

0.75

treatment_initiation_adjustment

adjustment to current ART coverage levels to account for defaulters

Real

1.0

vs_adjustment

adjustment to current viral suppression levels to account for defaulters

Real

1.0

prob_hiv_test_at_anc_or_delivery

probability of a women having hiv test at anc or following delivery

Real

0.95

prob_hiv_test_for_newborn_infant

probability of a newborn infant having HIV test pre-discharge

Real

0.95

prob_start_art_or_vs

Probability that a person will start treatment and be virally suppressed following testing

Dataframe

prob_behav_chg_after_hiv_test

Probability that a person will change risk behaviours, if HIV-negative, following testing

Real

0.5

prob_prep_for_fsw_after_hiv_test

Probability that a FSW will start PrEP, if HIV-negative, following testing

Real

0.05

prob_prep_for_agyw

Probability that adolescent girls / young women will start PrEP

Real

0.0

prob_circ_after_hiv_test

Probability that a male will be circumcised, if HIV-negative, following testing

Real

0.05

prob_circ_for_child_before_2020

Probability that a male aging <15 yrs will be circumcised before year 2020

Real

0.0128

prob_circ_for_child_from_2020

Probability that a male aging <15 yrs will be circumcised from year 2020, which is different from before 2020 as children vmmc policy/fund/cases has changed, according to PEPFAR 2020 Country Operational Plan and DHIS2 data

Real

0.0008

probability_of_being_retained_on_prep_every_3_months

Probability that someone who has initiated on prep will attend an appointment and be on prep for the next 3 months, until the next appointment.

Real

0.5

probability_of_being_retained_on_art_every_3_months

Probability that someone who has initiated on treatment will attend an appointment and be on treatment for next 3 months, until the next appointment.

Real

0.95

probability_of_seeking_further_art_appointment_if_drug_not_available

Probability that a person who ‘should’ be on art will seek another appointment (the following day and try for each of the next 7 days) if drugs were not available.

Real

0.9

probability_of_seeking_further_art_appointment_if_appointment_not_available

Probability that a person who ‘should’ be on art will seek another appointment if the health-system has not been able to provide them with an appointment

Real

0.9

prep_start_year

Year from which PrEP is available

Real

2018.0

ART_age_cutoff_young_child

Age cutoff for ART regimen for young children

Integer

1

ART_age_cutoff_older_child

Age cutoff for ART regimen for older children

Integer

10

rel_probability_art_baseline_aids

relative probability of person with HIV infection over 10 years being on ART at baseline

Real

10.0

aids_tb_treatment_adjustment

probability of death if aids and tb, person on treatment for tb

Real

0.5

hiv_healthseekingbehaviour_cap

number of repeat visits assumed for healthcare services

Integer

5

dispensation_period_months

length of prescription for ARVs in months, same for all PLHIV

Real

3.0

length_of_inpatient_stay_if_terminal

length in days of inpatient stay for end-of-life HIV patients: list has two elements [low-bound-inclusive, high-bound-exclusive]

List

[14, 20]

type_of_scaleup

argument to determine type scale-up of program which will be implemented, can be ‘none’, ‘target’ or ‘max’

String

none

scaleup_start_year

the year when the scale-up starts (it will occur on 1st January of that year)

Integer

2025

scaleup_parameters

the parameters and values changed in scenario analysis

Dataframe

time_inf

year

probability_infection

scaled_prob

Unnamed: 3

Unnamed: 4

Unnamed: 5

Distribution by CD4 count - HIV+ not on ART (15+) - (Male+Female)

Unnamed: 7

Unnamed: 8

Unnamed: 9

Unnamed: 10

Unnamed: 11

Unnamed: 12

Unnamed: 13

Unnamed: 14

Unnamed: 15

Unnamed: 16

20

0.0145011

0.0167087

nan

nan

nan

malawi_2021_v14_aim_v6.07

nan

nan

nan

nan

nan

nan

nan

nan

nan

nan

19

0.018403

0.0212047

nan

nan

nan

2010

150189.14229

134383.22199

114415.4995

52950.4893

77739.93484

28957.76557

20245.60225

578882

276528

0.350438

18

0.022511

0.0259382

nan

nan

nan

nan

nan

nan

nan

nan

nan

nan

nan

nan

nan

nan

17

0.0264052

0.0304252

nan

nan

nan

Distribution by CD4 count - HIV+ on ART (15+) - (Male+Female)

nan

nan

nan

nan

nan

nan

nan

nan

nan

nan

16

0.0305511

0.0352023

nan

nan

nan

nan

> 500

350 - 500

250 - 349

200 - 249

100 - 199

50 - 99

< 50

nan

nan

nan

15

0.0338398

0.0389916

nan

nan

nan

malawi_2021_v14_aim_v6.07

nan

nan

nan

nan

nan

nan

nan

nan

nan

nan

14

0.0383583

0.044198

nan

nan

nan

2010

6268.17276

5523.92113

4618.85403

44214.79861

77016.22359

36469.29667

36098.98313

210210

nan

nan

13

0.0423454

0.0487921

nan

nan

nan

nan

nan

nan

nan

nan

nan

nan

nan

nan

nan

nan

12

0.0452294

0.0521152

nan

nan

nan

nan

nan

nan

nan

nan

nan

nan

nan

nan

nan

nan

Only first 10 rows of 21 are shown.

art_coverage

year

age

single_age

sex

art_coverage

prop_coverage

2009

0_4

1

F

10.69

0.1069

2009

0_4

2

F

10.69

0.1069

2009

0_4

3

F

10.69

0.1069

2009

0_4

4

F

10.69

0.1069

2009

5_9

5

F

7.6

0.076

2009

5_9

6

F

7.6

0.076

2009

5_9

7

F

7.6

0.076

2009

5_9

8

F

7.6

0.076

2009

5_9

9

F

7.6

0.076

Only first 10 rows of 1662 are shown.

treatment_cascade

year

age

plhiv

know_status

on_art

plhiv_virally_suppressed

prob_art_if_dx

virally_suppressed_on_art

vs_assumed_value

2011

adults

100

73.2277

37.6375

nan

0.513979

80

yes

2012

adults

100

76.423

46.3159

42.1013

0.606046

91

no

2013

adults

100

78.7843

52.9497

47.6735

0.672084

90

no

2014

adults

100

80.8733

59.2378

51.5664

0.732477

87

no

2015

adults

100

82.7952

64.1071

57.269

0.774285

89

no

2016

adults

100

85.3839

71.6873

65.3256

0.839588

91

no

2017

adults

100

88.3281

78.056

69.322

0.883705

89

no

2018

adults

100

90.6581

84.2257

76.8029

0.929047

91

no

2019

adults

100

92.1484

85.4227

79.9867

0.927012

94

no

Only first 10 rows of 32 are shown.

hiv_testing_rates

year

adults_15plus

children0_14

total

pop_size_children0_14

pop_size_adults15plus

annual_testing_rate_children

annual_testing_rate_adults

annual_testing_rate_all_ages

testing_yield

2011

1.47766e+06

147536

1.62766e+06

6.84823e+06

8.2137e+06

0.0215437

0.179902

0.108065

nan

2012

1.54915e+06

149514

1.70682e+06

6.94965e+06

8.51109e+06

0.0215139

0.182016

0.110397

nan

2013

1.56574e+06

136888

1.70263e+06

7.04596e+06

8.8196e+06

0.0194279

0.177529

0.107316

nan

2014

1.73309e+06

161964

1.89506e+06

7.13959e+06

9.13714e+06

0.0226853

0.189676

0.116427

nan

2015

2.01048e+06

215807

2.22629e+06

7.23293e+06

9.46126e+06

0.0298367

0.212496

0.133357

nan

2016

2.91753e+06

483515

3.40104e+06

7.32839e+06

9.79171e+06

0.0659783

0.297959

0.198658

nan

2017

3.62603e+06

539283

4.16531e+06

7.42836e+06

1.01303e+07

0.0725978

0.35794

0.237223

0.023

2018

4.09092e+06

544240

4.63516e+06

7.53526e+06

1.04771e+07

0.0722257

0.390464

0.257332

0.01925

2019

3.64886e+06

418104

4.06697e+06

7.66667e+06

1.09056e+07

0.0545353

0.334586

0.218981

0.01425

Only first 10 rows of 41 are shown.

prob_start_art_or_vs

year

age

plhiv

know_status

on_art

plhiv_virally_suppressed

prob_art_if_dx

virally_suppressed_on_art

vs_assumed_value

2011

adults

100

73.2277

37.6375

nan

0.513979

80

yes

2012

adults

100

76.423

46.3159

42.1013

0.606046

91

no

2013

adults

100

78.7843

52.9497

47.6735

0.672084

90

no

2014

adults

100

80.8733

59.2378

51.5664

0.732477

87

no

2015

adults

100

82.7952

64.1071

57.269

0.774285

89

no

2016

adults

100

85.3839

71.6873

65.3256

0.839588

91

no

2017

adults

100

88.3281

78.056

69.322

0.883705

89

no

2018

adults

100

90.6581

84.2257

76.8029

0.929047

91

no

2019

adults

100

92.1484

85.4227

79.9867

0.927012

94

no

Only first 10 rows of 32 are shown.

scaleup_parameters

parameter

target_value

min_value

max_value

reduction_in_hiv_beta

0.9

1

0

prob_prep_for_fsw_after_hiv_test

0.5

0

1

prob_prep_for_agyw

0.1

0

1

probability_of_being_retained_on_prep_every_3_months

0.75

0

1

probability_of_being_retained_on_art_every_3_months

1

0

1

prob_circ_after_hiv_test

0.25

0

1

annual_testing_rate_adults

0.4

0

1

prob_hiv_test_at_anc_or_delivery

0.95

0

1

prob_hiv_test_for_newborn_infant

0.95

0

1

virally_suppressed_on_art

95

0

100

Labour

Name

Description

Type

Value

intercept_parity_lr2010

intercept value for linear regression equation predicating womens parity at 2010 baseline

List

[-2.81, -2.81]

effect_age_parity_lr2010

effect of an increase in age by 1 year in the linear regression equation predicating womens parity at 2010 baseline

List

[0.21, 0.21]

effect_mar_stat_2_parity_lr2010

effect of a change in marriage status from comparison (level 1) in the linear regression equation predicating womans parity at 2010 baseline

List

[0.84, 0.84]

effect_mar_stat_3_parity_lr2010

effect of a change in marriage status from comparison (level 1) in the linear regression equation predicating womans parity at 2010 baseline

List

[0.14, 0.14]

effect_wealth_lev_4_parity_lr2010

effect of an increase in wealth level in the linear regression equation predicating womans parity at 2010 base line

List

[-0.09, -0.09]

effect_wealth_lev_3_parity_lr2010

effect of an increase in wealth level in the linear regression equation predicating womans parity at 2010 base line

List

[-0.18, -0.18]

effect_wealth_lev_2_parity_lr2010

effect of an increase in wealth level in the linear regression equation predicating womans parity at 2010 base line

List

[-0.22, -0.22]

effect_wealth_lev_1_parity_lr2010

effect of an increase in wealth level in the linear regression equation predicating womans parity at 2010 base line

List

[-0.48, -0.48]

effect_edu_lev_2_parity_lr2010

effect of an increase in education level in the linear regression equation predicating womans parity at 2010 base line

List

[-0.33, -0.33]

effect_edu_lev_3_parity_lr2010

effect of an increase in education level in the linear regression equation predicating womans parity at 2010 base line

List

[-1, -1]

effect_rural_parity_lr2010

effect of rural living in the linear regression equation predicating womans parity at 2010 base line

List

[0.19, 0.19]

prob_previous_caesarean_at_baseline

probability of previously having delivered via caesarean section at baseline

List

[0.046, 0.046]

risk_post_term_labour

risk of remaining pregnant past 42 weeks

List

[0.077, 0.077]

rr_potl_bmi_30_35

effect of maternal BMI being between 30 and 35 on risk of post term labour

List

[1.42, 1.42]

rr_potl_bmi_35+

effect of maternal BMI being between above 35 on risk of post term labour

List

[1.55, 1.55]

list_limits_for_defining_term_status

List of number of days of gestation used to define term, early preterm, late preterm and post term delivery

List

[[259, 293, 148, 230, 231, 258, 294], [259, 293, 148, 230, 231, 258, 294]]

allowed_interventions

list of interventions allowed to run, used in analysis

List

[[‘prophylactic_labour_interventions’, ‘assessment_and_treatment_of_severe_pre_eclampsia’, ‘assessment_and_treatment_of_obstructed_labour’, ‘assessment_and_treatment_of_maternal_sepsis’, ‘assessment_and_treatment_of_hypertension’, ‘assessment_and_treatment_of_eclampsia’, ‘assessment_and_plan_for_referral_antepartum_haemorrhage’, ‘assessment_and_plan_for_referral_uterine_rupture’, ‘active_management_of_the_third_stage_of_labour’, ‘assessment_and_treatment_of_pph_retained_placenta’, ‘assessment_and_treatment_of_pph_uterine_atony’], [‘prophylactic_labour_interventions’, ‘assessment_and_treatment_of_severe_pre_eclampsia’, ‘assessment_and_treatment_of_obstructed_labour’, ‘assessment_and_treatment_of_maternal_sepsis’, ‘assessment_and_treatment_of_hypertension’, ‘assessment_and_treatment_of_eclampsia’, ‘assessment_and_plan_for_referral_antepartum_haemorrhage’, ‘assessment_and_plan_for_referral_uterine_rupture’, ‘active_management_of_the_third_stage_of_labour’, ‘assessment_and_treatment_of_pph_retained_placenta’, ‘assessment_and_treatment_of_pph_uterine_atony’]]

mean_birth_weights

list of mean birth weights from gestational age at birth 24-41 weeks

List

[[657, 746, 851, 966, 1096, 1240, 1440, 1641, 1841, 2041, 2242, 2442, 2736, 2856, 2995, 3036, 3117, 3136], [657, 746, 851, 966, 1096, 1240, 1440, 1641, 1841, 2041, 2242, 2442, 2736, 2856, 2995, 3036, 3117, 3136]]

standard_deviation_birth_weights

list of standard deviations associated with mean birth weights from gestational age at birth 24-41 weeks

List

[[113, 140, 169, 196, 218, 235, 274, 312, 351, 390, 428, 460, 467, 398, 356, 351, 396, 351], [113, 140, 169, 196, 218, 235, 274, 312, 351, 390, 428, 460, 467, 398, 356, 351, 396, 351]]

residual_prob_of_macrosomia

probability that those allocated to be normal birth weight and above will be macrosomic (>4kg)

List

[0.057, 0.057]

prob_obstruction_cpd

risk of a woman developing obstructed labour secondary to cephalopelvic disproportion

List

[0.012, 0.022]

rr_obstruction_cpd_stunted_mother

relative risk of obstruction secondary to CPD in mothers who are stunted

List

[2.4, 2.4]

rr_obstruction_foetal_macrosomia

relative risk of obstruction secondary to CPD in mothers who are carrying a macrosomic foetus

List

[3.3, 3.3]

prob_obstruction_malpos_malpres

risk of a woman developing obstructed labour secondary to malposition or malpresentation

List

[0.005, 0.009]

prob_obstruction_other

risk of a woman developing obstructed labour secondary to other causes

List

[0.0015, 0.0027]

prob_placental_abruption_during_labour

probability of a woman developing placental abruption during labour

List

[0.0005, 0.0005]

prob_aph_placenta_praevia_labour

probability of a woman with placenta praevia experiencing an APH during labour

List

[0.25, 0.25]

prob_aph_placental_abruption_labour

probability of a woman with placental abruption experiencing an APH during labour

List

[0.9, 0.9]

rr_placental_abruption_hypertension

Relative risk of placental abruption in women with hypertension

List

[2.2, 2.2]

rr_placental_abruption_previous_cs

Relative risk of placental abruption in women who delivered previously via caesarean section

List

[1.3, 1.3]

severity_maternal_haemorrhage

probability a maternal hemorrhage is non-severe (<1000mls) or severe (>1000mls)

List

[[0.8, 0.2], [0.8, 0.2]]

cfr_aph

case fatality rate for antepartum haemorrhage during labour

List

[0.11, 0.04]

prob_sepsis_chorioamnionitis

risk of sepsis following chorioamnionitis infection

List

[0.0002, 0.00018]

rr_sepsis_chorio_prom

relative risk of chorioamnionitis following PROM

List

[1.76, 1.76]

prob_sepsis_endometritis

risk of sepsis following endometritis

List

[6.9e-05, 6.2e-05]

rr_sepsis_endometritis_post_cs

relative risk of endometritis following caesarean delivery

List

[12.1, 12.1]

prob_sepsis_urinary_tract

risk of sepsis following urinary tract infection

List

[5.4e-05, 5.4e-05]

prob_sepsis_skin_soft_tissue

risk of sepsis following skin or soft tissue infection

List

[3.9e-05, 3.5e-05]

rr_sepsis_sst_post_cs

relative risk of skin/soft tissue sepsis following caesarean delivery

List

[3.9, 3.9]

cfr_sepsis

case fatality rate for sepsis during labour

List

[0.75, 0.49]

cfr_pp_sepsis

case fatality rate for sepsis following delivery

List

[0.75, 0.49]

prob_uterine_rupture

probability of a uterine rupture during labour

List

[0.0011, 0.0005]

rr_ur_parity_2

relative risk of uterine rupture in women who have delivered 2 times previously

List

[2.74, 2.74]

rr_ur_parity_3_or_4

relative risk of uterine rupture in women who have delivered 3-4 times previously

List

[4.89, 4.89]

rr_ur_parity_5+

relative risk of uterine rupture in women who have delivered > 5 times previously

List

[7.57, 7.57]

rr_ur_prev_cs

relative risk of uterine rupture in women who have previously delivered via caesarean section

List

[2.02, 2.02]

rr_ur_obstructed_labour

relative risk of uterine rupture in women who have been in obstructed labour

List

[23.6, 23.6]

cfr_uterine_rupture

case fatality rate for uterine rupture in labour

List

[0.65, 0.5]

prob_progression_gest_htn

probability of gestational hypertension progressing to severe gestational hypertensionduring/after labour

List

[0.036, 0.036]

prob_progression_severe_gest_htn

probability of severe gestational hypertension progressing to severe pre-eclampsia during/after labour

List

[0.13, 0.13]

prob_progression_mild_pre_eclamp

probability of mild pre-eclampsia progressing to severe pre-eclampsia during/after labour

List

[0.14, 0.14]

prob_progression_severe_pre_eclamp

probability of severe pre-eclampsia progressing to eclampsia during/after labour

List

[0.29, 0.29]

cfr_eclampsia

case fatality rate for eclampsia during labours

List

[0.028, 0.03]

cfr_severe_pre_eclamp

case fatality rate for severe pre eclampsia during labour

List

[0.018, 0.018]

prob_ip_still_birth

baseline probability of intrapartum still birth

List

[0.006, 0.005]

rr_still_birth_maternal_death

relative risk of still birth in mothers who have died during labour

List

[180, 180]

rr_still_birth_ur

relative risk of still birth in mothers experiencing uterine rupture

List

[56.6, 56.6]

rr_still_birth_ol

relative risk of still birth in mothers experiencing obstructed labour

List

[4.5, 4.5]

rr_still_birth_aph

relative risk of still birth in mothers experiencing antepartum haemorrhage

List

[2.1, 2.1]

rr_still_birth_hypertension

relative risk of still birth in mothers experiencing hypertension

List

[4.5, 4.5]

rr_still_birth_sepsis

relative risk of still birth in mothers experiencing intrapartum sepsis

List

[2, 2]

rr_still_birth_multiple_pregnancy

relative risk of still birth in mothers pregnant with twins

List

[3, 3]

prob_both_twins_ip_still_birth

probability that if this mother will experience still birth, and she is pregnant with twins, that neither baby will survive

List

[0.8, 0.8]

prob_pph_uterine_atony

risk of pph after experiencing uterine atony

List

[0.006, 0.011]

rr_pph_ua_hypertension

relative risk risk of pph after secondary to uterine atony in hypertensive women

List

[1.84, 1.84]

rr_pph_ua_multiple_pregnancy

relative risk risk of pph after secondary to uterine atony in women pregnant with twins

List

[2.16, 2.16]

rr_pph_ua_placental_abruption

relative risk risk of pph after secondary to uterine atony in women with placental abruption

List

[2.74, 2.74]

rr_pph_ua_macrosomia

relative risk risk of pph after secondary to uterine atony in women with macrosomic foetus

List

[1.46, 1.46]

rr_pph_ua_diabetes

risk of pph after experiencing uterine atony

List

[1.22, 1.22]

prob_pph_retained_placenta

risk of pph after experiencing retained placenta

List

[0.001, 0.0016]

prob_pph_other_causes

risk of pph after experiencing other pph causes

List

[0.0007, 0.001]

cfr_pp_pph

case fatality rate for postpartum haemorrhage

List

[0.22, 0.08]

rr_death_from_haem_with_anaemia

relative risk increase of death in women who are anaemic at time of PPH

List

[1.5, 1.5]

odds_deliver_in_health_centre

odds of a woman delivering in a health centre compared to a hospital

List

[0.69, 1.08]

rrr_hc_delivery_age_20_24

relative risk ratio for a woman aged 20-24 delivering in a health centre compared to a hospital

List

[0.79, 1]

rrr_hc_delivery_age_25_29

relative risk ratio for a woman aged 25-29 delivering in a health centre compared to a hospital

List

[0.5, 0.56]

rrr_hc_delivery_age_30_34

relative risk ratio for a woman aged 30-34 delivering in a health centre compared to a hospital

List

[0.27, 0.32]

rrr_hc_delivery_age_35_39

relative risk ratio for a woman aged 35-39 delivering in a health centre compared to a hospital

List

[0.13, 0.14]

rrr_hc_delivery_age_40_44

relative risk ratio for a woman aged 40-44 delivering in a health centre compared to a hospital

List

[0.06, 0.07]

rrr_hc_delivery_age_45_49

relative risk ratio for a woman aged 45-49 delivering in a health centre compared to a hospital

List

[0.02, 0.03]

rrr_hc_delivery_wealth_4

relative risk ratio of a woman at wealth level 4 delivering at health centre compared to a hospital

List

[0.82, 0.79]

rrr_hc_delivery_wealth_3

relative risk ratio of a woman at wealth level 3 delivering at health centre compared to a hospital

List

[0.77, 0.73]

rrr_hc_delivery_wealth_2

relative risk ratio of a woman at wealth level 2 delivering at health centre compared to a hospital

List

[0.62, 0.58]

rrr_hc_delivery_wealth_1

relative risk ratio of a woman at wealth level 1 delivering at health centre compared to a hospital

List

[0.55, 0.43]

rrr_hc_delivery_parity_3_to_4

relative risk ratio for a woman with a parity of 3-4 delivering in a health centre compared toa hospital

List

[2, 1.85]

rrr_hc_delivery_parity_>4

relative risk ratio of a woman with a parity >4 delivering in health centre compared to a hospital

List

[3.9, 3.8]

rrr_hc_delivery_rural

relative risk ratio of a married woman delivering in a health centre compared to a hospital

List

[1.99, 1.81]

rrr_hc_delivery_married

relative risk ratio of a married woman delivering in a health centre compared to a hospital

List

[1.3, 1.42]

odds_deliver_at_home

odds of a woman delivering at home compared to a hospital

List

[0.37, 0.09]

rrr_hb_delivery_age_20_24

relative risk ratio for a woman aged 20-24 delivering at home compared to a hospital

List

[1.42, 1]

rrr_hb_delivery_age_25_29

relative risk ratio for a woman aged 25-29 delivering at home compared to a hospital

List

[1, 0.58]

rrr_hb_delivery_age_30_34

relative risk ratio for a woman aged 30-34 delivering at home compared to a hospital

List

[0.42, 0.25]

rrr_hb_delivery_age_35_39

relative risk ratio for a woman aged 35-39 delivering at home compared to a hospital

List

[0.24, 0.16]

rrr_hb_delivery_age_40_44

relative risk ratio for a woman aged 40-44 delivering at home compared to a hospital

List

[0.12, 0.07]

rrr_hb_delivery_age_45_49

relative risk ratio for a woman aged 45-49 delivering at home compared to a hospital

List

[0.05, 0.04]

rrr_hb_delivery_rural

relative risk ratio of a rural delivering at home compared to a hospital

List

[1.73, 1]

rrr_hb_delivery_primary_education

relative risk ratio of a woman with a primary education delivering at home compared to a hospital

List

[0.76, 0.79]

rrr_hb_delivery_secondary_education

relative risk ratio of a woman with a secondary education delivering at home compared to a hospital

List

[0.46, 0.51]

rrr_hb_delivery_wealth_4

relative risk ratio of a woman at wealth level 4 delivering at home compared to a hospital

List

[0.82, 0.74]

rrr_hb_delivery_wealth_3

relative risk ratio of a woman at wealth level 3 delivering at home compared to a hospital

List

[0.72, 0.68]

rrr_hb_delivery_wealth_2

relative risk ratio of a woman at wealth level 2 delivering at home compared to a hospital

List

[0.41, 0.49]

rrr_hb_delivery_wealth_1

relative risk ratio of a woman at wealth level 1 delivering at home compared to a hospital

List

[0.2, 0.17]

rrr_hb_delivery_parity_3_to_4

relative risk ratio for a woman with a parity of 3-4 delivering at home compared toa hospital

List

[2.4, 1]

rrr_hb_delivery_parity_>4

relative risk ratio of a woman with a parity >4 delivering at home compared to a hospital

List

[5.25, 1]

rrr_hb_delivery_married

relative risk ratio of a married woman delivering in a home compared to a hospital

List

[0.63, 1]

probability_delivery_hospital

probability of delivering in a hospital

List

[0.32, 0.4]

prob_timings_pnc

probabilities that a woman who will receive a PNC check will receive care <48hrs post birth or > 48hrs post birth

List

[[0.85, 0.15], [0.88, 0.12]]

odds_will_attend_pnc

baseline odss a woman will seek PNC for her and her newborn following delivery

List

[0.9, 0.9]

or_pnc_age_30_35

odds ratio for women aged 30-35 attending PNC

List

[1.75, 1.75]

or_pnc_age_>35

odds ratio for women aged > 35 attending PNC

List

[1.86, 1.86]

or_pnc_rural

odds ratio for women who live rurally attending PNC

List

[0.55, 0.55]

or_pnc_wealth_level_1

odds ratio for women from the highest wealth level attending PNC

List

[0.72, 0.72]

or_pnc_anc4+

odds ratio for women who attended ANC4+ attending PNC

List

[1.2, 1.2]

or_pnc_caesarean_delivery

odds ratio for women who delivered by caesarean attending PNC

List

[1.93, 1.93]

or_pnc_facility_delivery

odds ratio for women who delivered in a health facility attending PNC

List

[1.91, 1.91]

or_pnc_parity_>4

odds ratio for women with a parity of >4 attending PNC

List

[0.03, 0.03]

probs_of_attending_pn_event_by_day

probabilities used in a weighted random draw to determine when a woman will attend the postnatal event

List

[[0.4, 0.3, 0.2, 0.05, 0.05], [0.4, 0.3, 0.2, 0.05, 0.05]]

prob_careseeking_for_complication

probability of a woman seeking skilled assistance after developing a complication at a home birth

List

[0.782, 0.782]

prob_careseeking_for_complication_pn

probability of a woman seeking skilled assistance after developing a postnatal complication following a home birth

List

[0.782, 0.782]

test_care_seeking_probs

dummy probabilities of delivery care seeking used in testing

List

[[0.33, 0.33, 0.34], [0.33, 0.33, 0.34]]

prob_delivery_modes_ec

probabilities that a woman admitted with eclampsia will deliver normally, via caesarean or via assisted vaginal delivery

List

[[0, 0, 1], [0, 0, 1]]

prob_delivery_modes_spe

probabilities that a woman admitted with severe pre-eclampsia will deliver normally, via caesarean or via assisted vaginal delivery

List

[[0.05, 0.05, 0.9], [0.05, 0.05, 0.9]]

residual_prob_avd

probabilities that a woman will deliver via assisted vaginal delivery for an indication not explicitly modelled

List

[0.128, 0.128]

residual_prob_caesarean

probabilities that a woman will deliver via caesarean section for an indication not explicitly modelled

List

[0.0188, 0.022]

prob_adherent_ifa

probability that a woman started on postnatal IFA will be adherent

List

[0.37, 0.34]

effect_of_ifa_for_resolving_anaemia

relative effect of iron and folic acid on anaemia status

List

[0.7, 0.7]

number_ifa_tablets_required_postnatally

total number of iron and folic acid tablets required during postnatal period

List

[93, 93]

treatment_effect_maternal_infection_clean_delivery

Effect of clean delivery practices on risk of maternal infection

List

[0.4, 0.4]

treatment_effect_maternal_chorio_abx_prom

Relative effect of antibiotics for premature rupture of membranes on maternal risk of chorioamnionitis prior to birth

List

[0.66, 0.66]

treatment_effect_amtsl

relative risk of severe postpartum haemorrhage following active management of the third stage of labour

List

[0.34, 0.34]

prob_haemostatis_uterotonics

probability of uterotonics stopping a postpartum haemorrhage due to uterine atony

List

[0.57, 0.57]

prob_successful_manual_removal_placenta

probability of manual removal of retained products arresting a post partum haemorrhage

List

[0.75, 0.75]

success_rate_pph_surgery

probability of surgery for postpartum haemorrhage being successful

List

[0.79, 0.79]

pph_treatment_effect_surg_md

effect of surgery on maternal death due to postpartum haemorrhage

List

[0.25, 0.25]

pph_treatment_effect_hyst_md

effect of hysterectomy on maternal death due to postpartum haemorrhage

List

[0.25, 0.25]

pph_bt_treatment_effect_md

effect of blood transfusion treatment for postpartum haemorrhage on risk of maternal death

List

[0.4, 0.4]

sepsis_treatment_effect_md

effect of treatment for sepsis on risk of maternal death

List

[0.2, 0.2]

success_rate_uterine_repair

probability repairing a ruptured uterus surgically

List

[0.83, 0.83]

prob_successful_assisted_vaginal_delivery

probability of successful assisted vaginal delivery

List

[0.7, 0.7]

ur_repair_treatment_effect_md

effect of surgical uterine repair treatment for uterine rupture on risk of maternal death

List

[0.25, 0.25]

ur_treatment_effect_bt_md

effect of blood transfusion treatment for uterine rupture on risk of maternal death

List

[0.4, 0.4]

ur_hysterectomy_treatment_effect_md

effect of blood hysterectomy for uterine rupture on risk of maternal death

List

[0.25, 0.25]

eclampsia_treatment_effect_severe_pe

effect of treatment for severe pre eclampsia on risk of eclampsia

List

[0.41, 0.41]

eclampsia_treatment_effect_md

effect of treatment for eclampsia on risk of maternal death

List

[0.4, 0.4]

anti_htns_treatment_effect_md

effect of IV anti hypertensive treatment on risk of death secondary to severe pre-eclampsia/eclampsia stillbirth

List

[0.5, 0.5]

anti_htns_treatment_effect_progression

effect of IV anti hypertensive treatment on risk of progression from mild to severe gestational hypertension

List

[0.49, 0.49]

aph_bt_treatment_effect_md

effect of blood transfusion treatment for antepartum haemorrhage on risk of maternal death

List

[0.4, 0.4]

treatment_effect_blood_transfusion_anaemia

effect of blood transfusion treatment for severe anaemia

List

[0.9, 0.9]

aph_cs_treatment_effect_md

effect of caesarean section for antepartum haemorrhage on risk of maternal death

List

[0.25, 0.25]

treatment_effect_avd_still_birth

effect of assisted vaginal delivery on risk of intrapartum still birth

List

[0.55, 0.55]

treatment_effect_cs_still_birth

effect of caesarean section delivery on risk of intrapartum still birth

List

[0.25, 0.25]

prob_hcw_avail_iv_abx

average probability that a health facility providing EmONC care has a HCW available that can delivery signal function - parenteral antibiotics

List

[0.99, 0.99]

prob_hcw_avail_uterotonic

average probability that a health facility providing EmONC care has a HCW available that can delivery signal function - parenteral uterotonics

List

[0.99, 0.99]

prob_hcw_avail_anticonvulsant

average probability that a health facility providing EmONC care has a HCW available that can delivery signal function - parenteral anticonvulsants

List

[0.93, 0.93]

prob_hcw_avail_man_r_placenta

average probability that a health facility providing EmONC care has a HCW available that can delivery signal function - manual removal of retained placenta

List

[0.82, 0.82]

prob_hcw_avail_avd

average probability that a health facility providing EmONC care has a HCW available that can delivery signal function - assisted vaginal delivery

List

[0.46, 0.46]

prob_hcw_avail_blood_tran

average probability that a health facility providing EmONC care has a HCW available that can delivery signal function - blood transfusion

List

[0.86, 0.86]

prob_hcw_avail_surg

average probability that a health facility providing EmONC care has a HCW available that can delivery signal function - obstetric surgery

List

[0.74, 0.74]

prob_hcw_avail_retained_prod

average probability that a health facility providing EmONC care has a HCW available that can delivery signal function - removal of retained products of conception

List

[0.49, 0.49]

prob_hcw_avail_neo_resus

average probability that a health facility providing EmONC care has a HCW available that can delivery signal function - neonatal resuscitation

List

[0.98, 0.98]

mean_hcw_competence_hc

mean competence of HCW at delivering EmONC care at a health centre. A draw below this level prevents intervention delivery

List

[[0.602, 0.602], [0.602, 0.602]]

mean_hcw_competence_hp

mean competence of HCW at delivering EmONC care at a hospital. A draw below this level prevents intervention delivery

List

[[0.662, 0.662], [0.662, 0.662]]

prob_intervention_delivered_anaemia_assessment_pnc

probability a woman will have their Hb levels checked during PNC given that the HSI has ran and the consumables are available (proxy for clinical quality)

List

[0.14, 0.18]

analysis_year

Year on which changes in parameters as part of analysis should be enacted (1st day, 1st month)

Integer

2023

la_analysis_in_progress

Used within the pregnancy_helper_function to signify that labour/postnatal analysis is currently being conducted

Boolean

False

alternative_bemonc_availability

parameter used in analysis to allow manipulation of coverage of BEmONC interventions

Boolean

False

alternative_cemonc_availability

parameter used in analysis to allow manipulation of coverage of CEmONC interventions

Boolean

False

bemonc_availability

set probability of BEmONC intervention being delivered during analysis

Real

1.0

cemonc_availability

set probability of CEmONC intervention being delivered during analysis

Real

1.0

bemonc_cons_availability

set probability of BEmONC consumables being available

Real

1.0

cemonc_cons_availability

set probability of CEmONC consumables being available

Real

1.0

alternative_pnc_coverage

Signals within the analysis event that an alternative level of PNC coverage has been determined following the events run

Boolean

False

alternative_pnc_quality

Signals within the analysis event that an alternative level of PNC quality has been determined following the events run

Boolean

False

pnc_availability_odds

Target odds of maternal PNC coverage when analysis is being conducted - only applied ifalternative_pnc_coverage is true

Real

3.0

pnc_availability_probability

Target probability of quality/consumables when analysis is being conducted - only applied if alternative_pnc_coverage is true

Real

1.0

sba_sens_analysis_max

Signals that max coverage of SBA is being forced for sensitivity analysis

Boolean

False

pnc_sens_analysis_max

Signals that max coverage of PNC is being forced for sensitivity analysis

Boolean

False

pnc_sens_analysis_min

Signals that min coverage of SBA is being forced for sensitivity analysis

Boolean

False

Lifestyle

Name

Description

Type

Value

init_p_urban

initial proportion urban

Dictionary

init_p_wealth_urban

List of probabilities of category given urban

List

[0.75, 0.16, 0.05, 0.02, 0.02]

init_p_wealth_rural

List of probabilities of category given rural

List

[0.11, 0.21, 0.22, 0.23, 0.23]

init_p_bmi_urban_m_not_high_sugar_age1529_not_tob_wealth1

List of probabilities of bmi categories for urban men age 15-29 with not high sugar, not tobacco, wealth level 1

List

[0.06, 0.8, 0.12, 0.01, 0.01]

init_or_higher_bmi_f

odds ratio higher BMI if female

Real

3.0

init_or_higher_bmi_rural

odds ratio higher BMI if rural

Real

0.6

init_or_higher_bmi_high_sugar

odds ratio higher BMI if high sugar intake

Real

1.1

init_or_higher_bmi_age3049

odds ratio higher BMI if age 30-49

Real

1.8

init_or_higher_bmi_agege50

odds ratio higher BMI if age ge 50

Real

2.7

init_or_higher_bmi_tob

odds ratio higher BMI if use tobacco

Real

0.7

init_or_higher_bmi_per_higher_wealth_level

odds ratio for higher initial bmi category per higher wealth level

Real

0.85

init_p_high_sugar

initital proportion with high sugar intake

Real

0.4

init_p_high_salt_urban

initital proportion with high salt intake

Real

0.2

init_or_high_salt_rural

odds ratio high salt if rural

Real

1.5

init_p_ex_alc_m

initital proportion of men with excess alcohol use

Real

0.15

init_p_ex_alc_f

initital proportion of women with excess alcohol use

Real

0.01

init_p_low_ex_urban_m

initital proportion of men with low exercise urban

Real

0.32

init_or_low_ex_rural

odds ratio low exercise rural

Real

0.4

init_or_low_ex_f

odds ratio low exercise female

Real

0.6

init_p_tob_age1519_m_wealth1

initial proportion of 15-19 year old men using tobacco, wealth level 1

Real

0.01

init_or_tob_f

odds ratio tobacco use females

Real

0.2

init_or_tob_age2039_m

odds ratio tobacco use age2039 in men

Real

4.0

init_or_tob_agege40_m

odds ratio tobacco use age40+ in men

Real

6.0

init_or_tob_wealth2

odds ratio tobacco use wealth level 2

Real

2.0

init_or_tob_wealth3

odds ratio tobacco use wealth level 3

Real

3.0

init_or_tob_wealth4

odds ratio tobacco use wealth level 4

Real

4.0

init_or_tob_wealth5

odds ratio tobacco use wealth level 5

Real

5.0

init_dist_mar_stat_age1520

proportions never, current, div_wid age 15-20 baseline

List

[0.7, 0.3, 0]

init_dist_mar_stat_age2030

proportions never, current, div_wid age 20-30 baseline

List

[0.15, 0.8, 0.05]

init_dist_mar_stat_age3040

proportions never, current, div_wid age 30-40 baseline

List

[0.05, 0.7, 0.25]

init_dist_mar_stat_age4050

proportions never, current, div_wid age 40-50 baseline

List

[0.03, 0.5, 0.47]

init_dist_mar_stat_age5060

proportions never, current, div_wid age 50-60 baseline

List

[0.03, 0.3, 0.67]

init_dist_mar_stat_agege60

proportions never, current, div_wid age 60+ baseline

List

[0.03, 0.2, 0.77]

init_age2030_w5_some_ed

proportions of low wealth 20-30 year olds with some education at baseline

Real

0.97

init_prop_age2030_w5_some_ed_sec

proportion of low wealth aged 20-30 with some education who have secondary education at baseline

Real

0.1

init_p_unimproved_sanitation_urban

initial probability of unimproved_sanitation given urban

Real

0.04

init_or_unimproved_sanitation_rural

initial odds ratio of unimproved_sanitation if rural

Real

4.5

init_p_no_clean_drinking_water_urban

initial probability of no_clean_drinking_water given urban

Real

0.017

init_or_no_clean_drinking_water_rural

initial odds ratio of no clean drinking_water if rural

Real

8.6

init_p_wood_burn_stove_urban

initial probability of wood_burn_stove given urban

Real

0.257

init_or_wood_burn_stove_rural

initial odds ratio of wood_burn_stove if rural

Real

40.0

init_p_no_access_handwashing_wealth1

initial probability of no_access_handwashing given wealth 1

Real

0.478

init_or_no_access_handwashing_per_lower_wealth

initial odds ratio of no_access_handwashing per lower wealth level

Real

1.06

init_prop_primary_edu

proportion of starting primary education at baseline age 5-12

Real

0.5

init_rp_some_ed_age0513

relative prevalence of some education at baseline age 5-13

Real

1.01

init_rp_some_ed_age1320

relative prevalence of some education at baseline age 13-20

Real

1.0

init_rp_some_ed_age2030

relative prevalence of some education at baseline age 20-30

Real

1.0

init_rp_some_ed_age3040

relative prevalence of some education at baseline age 30-40

Real

1.0

init_rp_some_ed_age4050

relative prevalence of some education at baseline age 40-50

Real

0.9

init_rp_some_ed_age5060

relative prevalence of some education at baseline age 50-60

Real

0.9

init_rp_some_ed_per_higher_wealth

relative prevalence of some education at baseline per higher wealth level

Real

1.005

init_rp_some_ed_sec_age1320

relative prevalence of secondary education age 15-20

Real

1.0

init_rp_some_ed_sec_age3040

relative prevalence of secondary education age 30-40

Real

0.8

init_rp_some_ed_sec_age4050

relative prevalence of secondary education age 40-50

Real

0.6

init_rp_some_ed_sec_age5060

relative prevalence of secondary education age 50-60

Real

0.4

init_rp_some_ed_sec_agege60

relative prevalence of secondary education age 60+

Real

0.2

init_rp_some_ed_agege60

relative prevalence of some education at baseline age age 60+

Real

0.9

init_rp_some_ed_sec_per_higher_wealth

relative prevalence of secondary education per higher wealth level

Real

1.48

r_urban

probability per 3 months of change from rural to urban

Real

0.0005

r_rural

probability per 3 months of change from urban to rural

Real

1e-05

r_higher_bmi

probability per 3 months of increase in bmi category if rural male age15-29 not using tobacoo with wealth level 1 with not high sugar intake

Real

0.0005

rr_higher_bmi_urban

probability per 3 months of increase in bmi category if

Real

1.5

rr_higher_bmi_f

rate ratio for increase in bmi category for females

Real

3.0

rr_higher_bmi_age3049

rate ratio for increase in bmi category for age 30-49

Real

1.8

rr_higher_bmi_agege50

rate ratio for increase in bmi category for age ge 50

Real

2.7

rr_higher_bmi_tob

rate ratio for increase in bmi category for tobacco users

Real

0.7

rr_higher_bmi_per_higher_wealth

rate ratio for increase in bmi category per higher wealth level

Real

0.85

rr_higher_bmi_high_sugar

rate ratio for increase in bmi category for high sugar intake

Real

1.2

r_lower_bmi

probability per 3 months of decrease in bmi category in non tobacco users

Real

0.001

rr_lower_bmi_tob

rate ratio for lower bmi category for tobacco users

Real

1.4

rr_lower_bmi_pop_advice_weight

probability per 3 months of decrease in bmi category given population advice/campaign on weight

Real

1.1

r_high_salt_urban

probability per 3 months of high salt intake if urban

Real

0.003

rr_high_salt_rural

rate ratio for high salt if rural

Real

1.5

r_not_high_salt

probability per 3 months of not high salt intake

Real

0.0001

rr_not_high_salt_pop_advice_salt

probability per 3 months of not high salt given population advice/campaign on salt

Real

1.1

r_high_sugar

probability per 3 months of high sugar intake

Real

0.0001

r_not_high_sugar

probability per 3 months of not high sugar intake

Real

0.0001

rr_not_high_sugar_pop_advice_sugar

probability per 3 months of not high sugar given population advice/campaign on sugar

Real

1.1

r_low_ex

probability per 3 months of change from not low exercise to low exercise

Real

0.001

r_not_low_ex

probability per 3 months of change from low exercise to not low exercie

Real

0.0001

rr_not_low_ex_pop_advice_exercise

probability per 3 months of not low exercise population advice/campaign on exercise

Real

1.1

rr_low_ex_f

risk ratio for becoming low exercise if female rather than male

Real

0.6

rr_low_ex_urban

risk ratio for becoming low exercise if urban rather than rural

Real

2.0

r_tob

probability per 3 months of change from not using tobacco to using tobacco if male age 15-19 wealth level 1

Real

0.0004

r_not_tob

probability per 3 months of change from tobacco using to not tobacco using

Real

0.0001

rr_tob_f

rate ratio tobacco if female

Real

0.1

rr_tob_age2039

risk ratio for tobacco using if age 20-39 compared with 15-19

Real

1.2

rr_tob_agege40

risk ratio for tobacco using if age >= 40 compared with 15-19

Real

1.5

rr_tob_wealth

risk ratio for tobacco using per 1 higher wealth level (higher wealth level = lower wealth)

Real

1.3

rr_not_tob_pop_advice_tobacco

probability per 3 months of quitting tobacco given population advice/campaign on tobacco

Real

1.1

r_ex_alc

probability per 3 months of change from not excess alcohol to excess alcohol

Real

0.003

r_not_ex_alc

probability per 3 months of change from excess alcohol to not excess alcohol

Real

0.0001

rr_ex_alc_f

risk ratio for becoming excess alcohol if female rather than male

Real

0.07

rr_not_ex_alc_pop_advice_alcohol

probability per 3 months of not excess alcohol given population advice/campaign on alcohol

Real

1.1

r_mar

probability per 3 months of marriage when age 15-30

Real

0.03

r_div_wid

probability per 3 months of becoming divorced or widowed, amongst those married

Real

0.01

r_stop_ed

probabilities per 3 months of stopping education if wealth level 5

Real

0.007

rr_stop_ed_lower_wealth

relative rate of stopping education per 1 lower wealth quantile

Real

1.5

p_ed_primary

probability at age 5 that start primary education if wealth level 5

Real

0.9

rp_ed_primary_higher_wealth

relative probability of starting school per 1 higher wealth level

Real

1.1

p_ed_secondary

probability at age 13 that start secondary education at 13 if in primary education and wealth level 5

Real

0.8

rp_ed_secondary_higher_wealth

relative probability of starting secondary school per 1 higher wealth level

Real

1.05

r_improved_sanitation

probability per 3 months of change from unimproved_sanitation true to false

Real

0.001

r_clean_drinking_water

probability per 3 months of change from drinking_water true to false

Real

0.001

r_non_wood_burn_stove

probability per 3 months of change from wood_burn_stove true to false

Real

0.001

r_access_handwashing

probability per 3 months of change from no access hand washing true to false

Real

0.001

start_date_campaign_exercise_increase

Date of campaign start for increased exercise

Date

2010-07-01 00:00:00

start_date_campaign_quit_smoking

Date of campaign start to quit smoking

Date

2010-07-01 00:00:00

start_date_campaign_alcohol_reduction

Date of campaign start for alcohol reduction

Date

2010-07-01 00:00:00

proportion_of_men_that_are_assumed_to_be_circumcised_at_birth

Proportion of men that are assumed to be circumcised at birth.The men are assumed to be circumcised at birth.

Real

0.2128

proportion_of_men_circumcised_at_initiation

Proportion of men (of all ages) that are assumed to be circumcised at the initiation of thesimulation.

Real

0.2128

proportion_female_sex_workers

proportion of women aged 15-49 years who are sex workers

Real

0.0069

fsw_transition

proportion of sex workers that stop being a sex worker each year

Real

0.18181818181818182

init_p_urban

prop_urban

Chitipa

Karonga

Nkhata Bay

Rumphi

Mzimba

Likoma

Mzuzu

Mzuzu City

Kasungu

Nkhotakota

Ntchisi

Dowa

Salima

Lilongwe

Lilongwe City

Mchinji

Dedza

Ntcheu

Mangochi

Machinga

Zomba

Zomba City

Chiradzulu

Blantyre

Blantyre City

Mwanza

Thyolo

Mulanje

Phalombe

Chikwawa

Nsanje

Balaka

Neno

0.1846

0.2644

0.1716

0.2188

0.0386

0.1503

0

1

0.2029

0.1372

0.1372

0.1379

0.1924

0

1

0.1486

0.1383

0.1118

0.1642

0.1499

0

1

0.0635

0

1

0.2536

0.1111

0.1149

0.0897

0.1171

0.2053

0.1836

0.1015

Malaria

Name

Description

Type

Value

interv

data frame of intervention coverage by year

Dataframe

clin_inc

data frame of clinical incidence by age, district, intervention coverage

Dataframe

inf_inc

data frame of infection incidence by age, district, intervention coverage

Dataframe

sev_inc

data frame of severe case incidence by age, district, intervention coverage

Dataframe

itn_district

data frame of ITN usage rates by district

Dataframe

irs_district

data frame of IRS usage rates by district

Dataframe

sev_symp_prob

probabilities of each symptom for severe malaria cases

Dataframe

sensitivity_rdt

Sensitivity of rdt

Real

0.95

cfr

case-fatality rate for severe malaria

Real

0.15

dur_asym

duration (days) of asymptomatic malaria

Real

110.0

dur_clin

duration (days) of clinical symptoms of malaria

Real

5.0

dur_clin_para

duration (days) of parasitaemia for clinical malaria cases

Real

195.0

treatment_adjustment

probability of death from severe malaria if on treatment

Real

0.5

p_sev_anaemia_preg

probability of severe anaemia in pregnant women with clinical malaria

Real

0.075

mortality_adjust

adjustment of case-fatality rate to match WHO/MAP

Real

10.0

data_end

final year of ICL malaria model outputs, after 2018 = projections

Real

2018.0

irs_rates_boundary

threshold for indoor residual spraying coverage

Real

0.5

irs_rates_upper

indoor residual spraying high coverage

Real

0.8

irs_rates_lower

indoor residual spraying low coverage

Real

0.0

prob_malaria_case_tests

probability that a malaria case will have a scheduled rdt

Real

0.4

itn

projected future itn coverage

Real

0.6

rdt_testing_rates

per capita rdt testing rate of general population

Dataframe

scaling_factor_for_rdt_availability

scaling factor applied to the reports of rdt usage to compensate fornon-availability of rdts at some facilities

Real

1.2

duration_iptp_protection_weeks

duration of protection against clinical malaria conferred by each dose of IPTp

Real

6.0

rr_clinical_malaria_hiv_under5

relative risk of clinical malaria if HIV+ and aged under 5 years

Real

1.7

rr_clinical_malaria_hiv_over5

relative risk of clinical malaria if HIV+ and aged over 5 years

Real

2.6

rr_clinical_malaria_hiv_pregnant

relative risk of clinical malaria if HIV+ and pregnant

Real

3.96

rr_clinical_malaria_cotrimoxazole

relative risk of clinical malaria if on cotrimoxazole

Real

0.58

rr_clinical_malaria_art

relative risk of clinical malaria if HIV+ and on ART and virally suppressed

Real

0.74

rr_clinical_malaria_iptp

relative risk of clinical malaria with each dose of IPTp

Real

0.54

rr_severe_malaria_hiv_under5

relative risk of severe malaria if HIV+ and aged under 5 years

Real

9.69

rr_severe_malaria_hiv_over5

relative risk of severe malaria if HIV+ and aged over 5 years

Real

2.68

rr_severe_malaria_hiv_pregnant

relative risk of clinical malaria if HIV+ and pregnant

Real

2.8

rr_severe_malaria_iptp

relative risk of severe malaria with each dose of IPTp

Real

0.6

prob_of_treatment_success

probability that treatment will clear malaria symptoms

Real

1.0

type_of_scaleup

argument to determine type scale-up of program which will be implemented, can be ‘none’, ‘target’ or ‘max’

String

none

scaleup_start_year

the year when the scale-up starts (it will occur on 1st January of that year)

Integer

2025

scaleup_parameters

the parameters and values changed in scenario analysis

Dataframe

interv

Year

ITN_coverage

IRS_coverage

ACT_coverage

MIS_sleptUnderITN

MIS_IPTp_1dose

MIS_IPTp_2dose

MIS_IPTp_3dose

2001

0

0

0

nan

nan

nan

nan

2002

0

0

0

nan

nan

nan

nan

2003

0.0337

0

0

0.02022

nan

nan

nan

2004

0.1149

0

0.011

0.06894

nan

nan

nan

2005

0.2636

0

0.0269

0.15816

nan

nan

nan

2006

0.2405

0

0.0538

0.1443

nan

nan

nan

2007

0.2865

0.00712375

0.0898

0.1719

nan

nan

nan

2008

0.3185

0.00698449

0.1382

0.1911

nan

nan

nan

2009

0.2908

0.0198598

0.2082

0.17448

nan

nan

nan

Only first 10 rows of 26 are shown.

clin_inc

Unnamed: 0

admin

llin

irs

month

inc_age_gp

clin_incidence

age

monthly_inc_clin

monthly_prob_clin

1

Balaka

0.1

0.8

2

clin_inc_0_0.5

0.616651

0

0.0513875

0.0500895

2

Balaka

0.1

0.8

3

clin_inc_0_0.5

0.724266

0

0.0603555

0.0585702

3

Balaka

0.1

0.8

4

clin_inc_0_0.5

0.487449

0

0.0406208

0.0398068

4

Balaka

0.1

0.8

5

clin_inc_0_0.5

0.221309

0

0.0184424

0.0182734

5

Balaka

0.1

0.8

6

clin_inc_0_0.5

0.0654417

0

0.00545347

0.00543863

6

Balaka

0.1

0.8

7

clin_inc_0_0.5

0.00924685

0

0.000770571

0.000770274

7

Balaka

0.1

0.8

8

clin_inc_0_0.5

0.0258359

0

0.00215299

0.00215068

8

Balaka

0.1

0.8

9

clin_inc_0_0.5

0.0592395

0

0.00493663

0.00492446

9

Balaka

0.1

0.8

10

clin_inc_0_0.5

0.0234651

0

0.00195542

0.00195351

Only first 10 rows of 497664 are shown.

inf_inc

Unnamed: 0

admin

llin

irs

month

inf_inc_age_gp

inf_incidence

age

monthly_inc_inf

monthly_prob_inf

1

Balaka

0.1

0.8

2

inf_inc_0_0.5

1.19984

0

0.0999865

0.0951504

2

Balaka

0.1

0.8

3

inf_inc_0_0.5

1.42709

0

0.118924

0.112125

3

Balaka

0.1

0.8

4

inf_inc_0_0.5

0.955087

0

0.0795906

0.0765057

4

Balaka

0.1

0.8

5

inf_inc_0_0.5

0.464054

0

0.0386712

0.037933

5

Balaka

0.1

0.8

6

inf_inc_0_0.5

0.122824

0

0.0102353

0.0101831

6

Balaka

0.1

0.8

7

inf_inc_0_0.5

0.0174689

0

0.00145575

0.00145469

7

Balaka

0.1

0.8

8

inf_inc_0_0.5

0.0559292

0

0.00466077

0.00464993

8

Balaka

0.1

0.8

9

inf_inc_0_0.5

0.110247

0

0.00918724

0.00914517

9

Balaka

0.1

0.8

10

inf_inc_0_0.5

0.0416001

0

0.00346667

0.00346067

Only first 10 rows of 497664 are shown.

sev_inc

Unnamed: 0

admin

llin

irs

month

sev_inc_age_gp

sev_incidence

age

monthly_inc_sev

monthly_prob_sev

1

Balaka

0.1

0.8

2

sev_inc_0_0.5

0.039965

0

0.00333041

0.00332487

2

Balaka

0.1

0.8

3

sev_inc_0_0.5

0.0449733

0

0.00374778

0.00374076

3

Balaka

0.1

0.8

4

sev_inc_0_0.5

0.0293607

0

0.00244672

0.00244373

4

Balaka

0.1

0.8

5

sev_inc_0_0.5

0.0133483

0

0.00111236

0.00111174

5

Balaka

0.1

0.8

6

sev_inc_0_0.5

0.00411232

0

0.000342693

0.000342634

6

Balaka

0.1

0.8

7

sev_inc_0_0.5

0.000551552

0

4.59627e-05

4.59616e-05

7

Balaka

0.1

0.8

8

sev_inc_0_0.5

0.00155992

0

0.000129993

0.000129985

8

Balaka

0.1

0.8

9

sev_inc_0_0.5

0.00409992

0

0.00034166

0.000341602

9

Balaka

0.1

0.8

10

sev_inc_0_0.5

0.00162945

0

0.000135787

0.000135778

Only first 10 rows of 497664 are shown.

itn_district

District

Year

itn_rate

Balaka

2011

0.3

Balaka

2012

0.5

Balaka

2013

0.7

Balaka

2014

0.6

Balaka

2015

0.4

Balaka

2016

0.6

Balaka

2017

0.6

Balaka

2018

0.6

Blantyre

2010

0.5

Only first 10 rows of 288 are shown.

irs_district

District

Year

irs_rate

Balaka

2011

0

Balaka

2012

0

Balaka

2013

0

Balaka

2014

0

Balaka

2015

0

Balaka

2016

0

Balaka

2017

0

Balaka

2018

0

Blantyre

2010

0

Only first 10 rows of 288 are shown.

sev_symp_prob

symptom

age_group

prop_lower

prop_upper

acidosis

0_5

0.4

0.45

coma_convulsions

0_5

0.3

0.4

renal_failure

0_5

0.05

0.15

severe_anaemia

0_5

0.4

0.5

shock

0_5

0.05

0.15

jaundice

5_60

0.1

0.6

acidosis

5_60

0.45

0.6

coma_convulsions

5_60

0.38

0.45

renal_failure

5_60

0.1

0.5

Only first 10 rows of 12 are shown.

rdt_testing_rates

Year

NumSuspectedCasesTestedByRDT

NumPositiveCasesTestedByRDT

NumSuspectedCasesTestedByMicroscopy

NumPositiveCasesTestedByMicroscopy

NumTreated

NumMalariaCases

TreatmentCoverage

Population

Rate_rdt_testing

2011

580708

253973

166959

50526

nan

5.46033e+06

nan

1.51461e+07

0.0383404

2012

2.76399e+06

1.28185e+06

103754

283138

nan

4.92953e+06

nan

1.55813e+07

0.177392

2013

3.02902e+06

1.23639e+06

129575

44501

nan

4.5475e+06

nan

1.60248e+07

0.189021

2014

5.34472e+06

2.82768e+06

127752

77635

nan

4.26516e+06

nan

1.6478e+07

0.324356

2015

7.03008e+06

3.58532e+06

240212

75923

nan

4.03294e+06

nan

1.69389e+07

0.415025

2016

8.66124e+06

4.73084e+06

216643

96538

nan

3.86857e+06

nan

1.74056e+07

0.497611

2017

9.41394e+06

4.90134e+06

198534

46099

nan

3.85109e+06

nan

1.78812e+07

0.526473

2018

1.13841e+07

5.83074e+06

132475

34735

7.04301e+06

3.78227e+06

1.86211

1.83679e+07

0.619783

2019

1.08613e+07

5.15378e+06

406907

30328

5.08972e+06

3.83515e+06

1.32712

1.88673e+07

0.575668

Only first 10 rows of 15 are shown.

scaleup_parameters

parameter

target_value

min_value

max_value

prob_malaria_case_tests

1

0

1

rdt_testing_rates

0.8

0

1

prob_of_treatment_success

1

0

1

irs_district

0.8

0

0.8

itn_district

0.7

0

0.7

itn

0.7

0

0.7

Measles

Name

Description

Type

Value

beta_baseline

Baseline measles transmission probability

Real

0.00216

beta_scale

Scale value for measles transmission probability sinusoidal function

Real

1.0

phase_shift

Phase shift for measles transmission probability sinusoidal function

Real

5.0

period

Period for measles transmission probability sinusoidal function

Real

12.0

vaccine_efficacy_1

Efficacy of first measles vaccine dose against measles infection

Real

0.85

vaccine_efficacy_2

Efficacy of second measles vaccine dose against measles infection

Real

0.99

prob_severe

Probability of severe measles infection, requiring hospitalisation

Real

0.05

risk_death_on_treatment

Risk of scheduled death occurring if on treatment for measles complications

Real

0.38

symptom_prob

Probability of each symptom with measles infection

Dataframe

case_fatality_rate

Probability that case of measles will result in death if not treated

Dictionary

symptom_prob

age

symptom

probability

1

rash

1

2

rash

1

3

rash

1

4

rash

1

5

rash

1

6

rash

1

7

rash

1

8

rash

1

9

rash

1

Only first 10 rows of 217 are shown.

case_fatality_rate

0

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

21

22

23

24

25

26

27

28

29

30

0.03

0.03

0.03

0.03

0.03

0.01

0.01

0.01

0.01

0.01

0.00333333

0.00333333

0.00333333

0.00333333

0.00333333

0.00333333

0.00333333

0.00333333

0.00333333

0.00333333

0.00333333

0.00333333

0.00333333

0.00333333

0.00333333

0.00333333

0.00333333

0.00333333

0.00333333

0.00333333

0.00333333

NewbornOutcomes

Name

Description

Type

Value

prob_care_seeking_for_complication

baseline probability that a mother will seek care for an unwell neonate following delivery

List

[0.782, 0.782]

prob_day_reaches_week_one_event

Probabilities for day of attendance at postnatal week one event

List

[[0.4, 0.3, 0.2, 0.05, 0.05], [0.4, 0.3, 0.2, 0.05, 0.05]]

prob_early_onset_neonatal_sepsis_day_0

baseline probability of a neonate developing early onset sepsis between birth and 24hrs

List

[0.02, 0.017]

rr_eons_maternal_chorio

relative risk of EONS in newborns whose mothers have chorioamnionitis

List

[6.6, 6.6]

rr_eons_maternal_prom

relative risk of EONS in newborns whose mothers have PROM

List

[4.9, 4.9]

rr_eons_preterm_neonate

relative risk of EONS in preterm newborns

List

[3.36, 3.36]

cfr_early_onset_sepsis

case fatality rate for a neonate due to neonatal sepsis

List

[0.064, 0.056]

cfr_late_onset_sepsis

case fatality rate for a neonate due to neonatal sepsis

List

[0.064, 0.056]

prob_mild_impairment_post_sepsis

probability of the mild neurodevelopmental impairment in survivors of sepsis

List

[0.12, 0.12]

prob_mod_severe_impairment_post_sepsis

probability of the moderate or severe neurodevelopmental impairment in survivors of sepsis

List

[0.23, 0.23]

prob_failure_to_transition

baseline probability of a neonate developing intrapartum related complications (previously birth asphyxia) following delivery

List

[0.01, 0.01]

prob_enceph_no_resus

Probability of a newborn who was not breathing at birth, and didnt receive resuscitation, developing encephalopathy

List

[0.5, 0.5]

cfr_failed_to_transition

case fatality rate for a neonate following failure to transition

List

[0.2, 0.2]

prob_encephalopathy

baseline odds of a neonate developing encephalopathy of any severity following birth

List

[0.0097, 0.0097]

rr_enceph_neonatal_sepsis

relative risk of neonatal encephalopathy if the neonate is also septic

List

[8.67, 8.67]

rr_enceph_obstructed_labour

relative risk for encephalopathy if the mothers labour was obstructed

List

[3.8, 3.8]

rr_enceph_acute_hypoxic_event

relative risk for encephalopathy if the mothers experience an acute event in labour

List

[8.74, 8.74]

prob_enceph_severity

probability of the severity of encephalopathy in a newborn who is encephalopathic

List

[[0.422, 0.338, 0.24], [0.422, 0.338, 0.24]]

prob_mild_impairment_post_enceph

probability of the mild neurodevelopmental impairment in survivors of encephalopathy

List

[0.21, 0.21]

prob_mod_severe_impairment_post_enceph

probability of the moderate or severe neurodevelopmental impairment in survivors of encephalopathy

List

[0.269, 0.269]

cfr_enceph

case fatality rate for a neonate due to mild encephalopathy

List

[0.48, 0.28]

cfr_multiplier_severe_enceph

multiplier for risk of death in a neonate with severe encephalopathy

List

[1.91, 3.28]

prob_respiratory_distress_preterm

probability that a preterm infant will experience respiratory distress at birth

List

[0.12, 0.12]

rr_rds_early_preterm

relative risk of RDS in a preterm newborn born before 34 weeks

List

[2.64, 2.64]

rr_rds_maternal_diabetes_mellitus

relative risk of RDS in a preterm newborn whose mother has DM

List

[2.66, 2.66]

rr_rds_maternal_gestational_diab

relative risk of RDS in a preterm newborn whose mother has gestational diabetes

List

[1.57, 1.57]

cfr_respiratory_distress_syndrome

case fatality rate for respiratory distress syndrome of prematurity

List

[0.29, 0.2]

prob_mild_disability_preterm_<32weeks

probability of mild long term neurodevelopmental disability in preterm infants born at less than 32 weeks gestation

List

[0.324, 0.324]

prob_mod_severe_disability_preterm_<32weeks

probability of moderate/severe longterm neurodevelopmental disability in preterm infants born at less than 32 weeks gestation

List

[0.246, 0.246]

prob_mild_disability_preterm_32_36weeks

probability of mild long term neurodevelopmental disability in preterm infants born between 32 and 36 weeks gestation

List

[0.034, 0.034]

prob_mod_severe_disability_preterm_32_36weeks

probability of moderate/severe long term neurodevelopmental disability in preterm infants born between 32 and 36 weeks gestation

List

[0.018, 0.018]

prob_retinopathy_preterm_early

Probability that a neonate born at less than 32 weeks who survives the neonatal period will develop retinopathy

List

[0.365, 0.365]

prob_retinopathy_preterm_late

Probability that a neonate born at less than 32 weeks who survives the neonatal period will develop retinopathy

List

[0.077, 0.077]

prob_retinopathy_severity_no_treatment

Probabilities that a preterm neonate who developed retinopathy will experience the following vision impairments: none, mild, moderate or blindness

List

[[0.28, 0.03, 0.1, 0.12, 0.47], [0.28, 0.03, 0.1, 0.12, 0.47]]

cfr_preterm_birth

case fatality rate for a neonate born prematurely

List

[0.0227, 0.0187]

rr_preterm_death_early_preterm

relative risk of preterm death in early preterm neonates

List

[1.66, 1.66]

prob_preterm_death_by_day

probability of death due to preterm complications occurring on days 0-14

List

[[0.4, 0.2, 0.15, 0.05, 0.02, 0.018, 0.018, 0.018, 0.018, 0.018, 0.018, 0.018, 0.018, 0.018, 0.018], [0.4, 0.2, 0.15, 0.05, 0.02, 0.018, 0.018, 0.018, 0.018, 0.018, 0.018, 0.018, 0.018, 0.018, 0.018]]

prob_congenital_heart_anomaly

Probability of a congenital heart anomaly in the newborn

List

[0.009, 0.009]

prob_limb_musc_skeletal_anomaly

Probability of a congenital limb or musculoskeletal anomaly in the newborn

List

[0.008, 0.008]

prob_urogenital_anomaly

Probability of a congenital urogenital anomaly in the newborn

List

[0.003, 0.003]

prob_digestive_anomaly

Probability of a congenital digestive anomaly in the newborn

List

[0.0007, 0.0007]

prob_other_anomaly

Probability of a other congenital anomalies in the newborn

List

[0.0004, 0.0004]

cfr_congenital_heart_anomaly

case fatality rate for newborns with congenital heart anomalies

List

[0.062, 0.062]

cfr_limb_or_musculoskeletal_anomaly

case fatality rate for newborns with congenital limb/musculoskeletal anomalies

List

[0.0069, 0.0069]

cfr_urogenital_anomaly

case fatality rate for newborns with congenital urogenital anomalies

List

[0.0085, 0.0085]

cfr_digestive_anomaly

case fatality rate for newborns with congenital digestive anomalies

List

[0.2829, 0.2829]

cfr_other_anomaly

case fatality rate for newborns with other congenital anomalies

List

[0.131, 0.131]

prob_cba_death_by_age_group

probabilities that death from a congenital birth anomaly will occur once the individual reaches the following age groups: early neonatal, late neonatal, post neonatal 1-4 years, 5-9 years, 10 -14 years or 15-69 years

List

[[0.27, 0.08, 0.38, 0.2, 0.02, 0.01, 0.04], [0.3, 0.09, 0.35, 0.18, 0.03, 0.02, 0.03]]

prob_early_breastfeeding_hb

probability that a neonate will be breastfed within the first hour following birth when delivered at home

List

[0.94, 0.67]

prob_breastfeeding_type

probabilities that a woman is 1.) not breastfeeding 2.) non-exclusively breastfeeding 3.)exclusively breastfeeding at birth (until 6 months)

List

[[0.005, 0.277, 0.718], [0.101, 0.289, 0.61]]

prob_early_breastfeeding_hf

probability that a neonate will be breastfed within the first hour following birth when delivered at a health facility

List

[0.94, 0.77]

prob_pnc_check_newborn

probability that a neonate will receive a full postnatal check

List

[0.6, 0.6]

prob_timings_pnc_newborns

probabilities that a postnatal check will happen before or after 48 hours alive

List

[[0.97, 0.03], [0.97, 0.03]]

prob_kmc_available

probability that KMC can be delivered in a given hospital

List

[0.62, 0.62]

treatment_effect_inj_abx_sep

effect of injectable antibiotics treatment on reducing mortality from sepsis

List

[0.35, 0.35]

treatment_effect_supp_care_sep

effect of full supportive care treatment on reducing mortality from sepsis

List

[0.2, 0.2]

treatment_effect_cord_care

effect of full supportive care treatment on reducing incidence of sepsis

List

[0.77, 0.77]

treatment_effect_clean_birth

effect of clean birth practices on reducing incidence of sepsis

List

[0.73, 0.73]

treatment_effect_early_init_bf

effect of early initiation of breastfeeding on reducing incidence of sepsis

List

[0.55, 0.55]

treatment_effect_resuscitation

effect of resuscitation on newborn mortality associated with encephalopathy

List

[0.63, 0.63]

treatment_effect_resuscitation_preterm

effect of resuscitation on newborn mortality associated with prematurity

List

[0.81, 0.81]

treatment_effect_abx_prom

effect of antibiotics given to mothers experience PROM on risk of newborn sepsis

List

[0.67, 0.67]

treatment_effect_steroid_preterm

relative risk of death for preterm neonates following administration of antenatal corticosteroids

List

[0.71, 0.71]

treatment_effect_kmc

treatment effect of kangaroo mother care on preterm mortality

List

[0.49, 0.49]

OesophagealCancer

Name

Description

Type

Value

init_prop_oes_cancer_stage

initial proportions in dysplasia/cancer categories for man aged 20 with no excess alcohol and no tobacco

List

[0.0003, 0.0001, 5e-06, 3e-05, 5e-05, 1e-05]

init_prop_dysphagia_oes_cancer_by_stage

initial proportions of those with dysplasia/cancer categories that have the symptom dysphagia

List

[0.01, 0.03, 0.1, 0.2, 0.3, 0.8]

init_prop_with_dysphagia_diagnosed_oes_cancer_by_stage

initial proportions of people that have symptom of dysphagia that have been diagnosed

List

[0.8, 0.85, 0.9, 0.95, 0.98, 0.9]

init_prop_treatment_status_oes_cancer

initial proportions of people with oesophageal dysplasia/cancer that had initiated treatment

List

[0.01, 0.01, 0.05, 0.05, 0.05, 0.05]

init_prob_palliative_care

initial probability of being under palliative care if in stage 4

Real

0.5

r_low_grade_dysplasia_none

probabilty per 3 months of incident low grade oesophageal dysplasia, amongst people with no oesophageal dysplasia (men, age20, no excess alcohol, no tobacco)

Real

5e-07

rr_low_grade_dysplasia_none_female

rate ratio for low grade oesophageal dysplasia for females

Real

1.3

rr_low_grade_dysplasia_none_per_year_older

rate ratio for low grade oesophageal dysplasia per year older from age 20

Real

1.1

rr_low_grade_dysplasia_none_tobacco

rate ratio for low grade oesophageal dysplasia for tobacco smokers

Real

2.0

rr_low_grade_dysplasia_none_ex_alc

rate ratio for low grade oesophageal dysplasia for no excess alcohol

Real

1.0

r_high_grade_dysplasia_low_grade_dysp

probabilty per 3 months of high grade oesophageal dysplasia, amongst people with low grade dysplasia

Real

0.03

rr_high_grade_dysp_undergone_curative_treatment

rate ratio for high grade dysplasia for people with low grade dysplasia if had curative treatment at low grade dysplasia stage

Real

0.1

r_stage1_high_grade_dysp

probabilty per 3 months of stage 1 oesophageal cancer amongst people with high grade dysplasia

Real

0.01

rr_stage1_undergone_curative_treatment

rate ratio for stage 1 oesophageal cancer for people with high grade dysplasia if had curative treatment at high grade dysplasia stage

Real

0.1

r_stage2_stage1

probabilty per 3 months of stage 2 oesophageal cancer amongst people with stage 1

Real

0.05

rr_stage2_undergone_curative_treatment

rate ratio for stage 2 oesophageal cancer for people with stage 1 oesophageal cancer if had curative treatment at stage 1

Real

0.1

r_stage3_stage2

probabilty per 3 months of stage 3 oesophageal cancer amongst people with stage 2

Real

0.05

rr_stage3_undergone_curative_treatment

rate ratio for stage 3 oesophageal cancer for people with stage 2 oesophageal cancer if had curative treatment at stage 2

Real

0.1

r_stage4_stage3

probabilty per 3 months of stage 4 oesophageal cancer amongst people with stage 3

Real

0.05

rr_stage4_undergone_curative_treatment

rate ratio for stage 4 oesophageal cancer for people with stage 3 oesophageal cancer if had curative treatment at stage 3

Real

0.3

rate_palliative_care_stage4

prob palliative care this 3 month period if stage4

Real

0.5

r_death_oesoph_cancer

probabilty per 3 months of death from oesophageal cancer mongst people with stage 4 oesophageal cancer

Real

0.4

rr_dysphagia_low_grade_dysp

probability per 3 months of dysphagia in a person with low grade oesophageal dysplasia

Real

1.0

rr_dysphagia_high_grade_dysp

rate ratio for dysphagia if have high grade oesophageal dysplasia

Real

1.0

r_dysphagia_stage1

rate ratio for dysphagia if have stage 1 oesophageal cancer

Real

0.01

rr_dysphagia_stage2

rate ratio for dysphagia if have stage 2 oesophageal cancer

Real

2.0

rr_dysphagia_stage3

rate ratio for dysphagia if have stage 3 oesophageal cancer

Real

50.0

rr_dysphagia_stage4

rate ratio for dysphagia if have stage 4 oesophageal cancer

Real

100.0

rp_oes_cancer_female

relative prevalence at baseline of oesophageal dysplasia/cancer if female

Real

1.3

rp_oes_cancer_per_year_older

relative prevalence at baseline of oesophageal dysplasia/cancer per year older than 20

Real

1.1

rp_oes_cancer_tobacco

relative prevalence at baseline of oesophageal dysplasia/cancer if tobacco

Real

2.0

rp_oes_cancer_ex_alc

relative prevalence at baseline of oesophageal dysplasia/cancer

Real

1.0

sensitivity_of_endoscopy_for_oes_cancer_with_dysphagia

sensitivity of endoscopy_for diagnosis of oesophageal cancer for those with dysphagia

Real

1.0

OtherAdultCancer

Name

Description

Type

Value

init_prop_early_other_adult_ca_symptom_other_adult_cancer_by_stage

initial proportions of those with other adult cancer categories that have other adult_ca_symptom

List

[0.3, 0.5, 0.8]

in_prop_other_adult_cancer_stage

initial proportions in other adult cancer stages for person aged 15-29

List

[0.0002, 0.0002, 0.0004]

init_prop_with_early_other_adult_ca_symptom_diagnosed_by_stage

initial proportions of people that have symptom of other_adult_ca_symptom that have been diagnosed

List

[0.3, 0.4, 0.5]

init_prop_treatment_status_other_adult_cancer

initial proportions of people with other_adult cancer previously given treatment

List

[0.1, 0.1, 0.1]

init_prob_palliative_care

initial probability of being under palliative care if in metastatic

Real

0.95

r_site_confined_none

probabilty per 3 months of incident site_confined other_adult cancer amongst people age 15-29 with no other adult cancer

Real

1e-05

rr_site_confined_age3049

rate ratio for site-confined other_adult cancer for age 30-49

Real

5.0

rr_site_confined_age5069

rate ratio for site-confined other_adult cancer for age 50-69

Real

21.0

rr_site_confined_agege70

rate ratio for site-confined other_adult cancer for age ge 70

Real

60.0

rr_site_confined_hiv

rate ratio for site-confined other_adult_cancer if infected with HIV

Real

4.13

r_local_ln_site_confined_other_adult_ca

probabilty per 3 months of local ln other_adult cancer amongst people with site confined

Real

0.15

rr_local_ln_other_adult_ca_undergone_curative_treatment

rate ratio for local_ln for people with site_confined if had curative treatment at site_confined stage

Real

0.1

r_metastatic_local_ln

probabilty per 3 months of metastatic other_adult cancer amongst people with local_ln

Real

0.15

rr_metastatic_undergone_curative_treatment

rate ratio for metastatic Other_adult cancer for people with local_lnOther_adult cancer if had curative treatment at local_ln

Real

0.2

r_death_other_adult_cancer

probabilty per 3 months of death from other adult cancer mongst people with metastatic other_adult cancer

Real

0.2

r_early_other_adult_ca_symptom_site_confined_other_adult_ca

probability per 3 months of other_adult_ca_symptom in a person with site confined other_adult cancer

Real

0.02

rr_early_other_adult_ca_symptom_local_ln_other_adult_ca

rate ratio for other_adult_ca_symptom if have high grade other_adult cancer

Real

3.0

rr_early_other_adult_ca_symptom_metastatic_other_adult_ca

rate ratio for other_adult_ca_symptom if have metastatic other_adult cancer

Real

10.0

rp_other_adult_cancer_age3049

relative prevalence at baseline of bladder cancer/cancer age 30-49

Real

1.5

rp_other_adult_cancer_age5069

relative prevalence at baseline of bladder cancer/cancer age 50-69

Real

2.0

rp_other_adult_cancer_agege70

relative prevalence at baseline of bladder cancer/cancer age 70+

Real

4.0

sensitivity_of_diagnostic_device_for_other_adult_cancer_with_other_adult_ca_site_confined

sensitivity of diagnostic_device_for diagnosis of other_adult cancer for those with other_adult_ca_site-confined

Real

0.8

sensitivity_of_diagnostic_device_for_other_adult_cancer_with_other_adult_ca_local_ln

sensitivity of diagnostic_device_for diagnosis of other_adult cancer for those with other_adult_local_ln

Real

0.95

sensitivity_of_diagnostic_device_for_other_adult_cancer_with_other_adult_ca_metastatic

sensitivity of diagnostic_device_for diagnosis of other_adult cancer for those with other_adult_ca metastatic

Real

0.95

PostnatalSupervisor

Name

Description

Type

Value

prob_obstetric_fistula

probability of a woman developing an obstetric fistula after birth

List

[0.00426, 0.00426]

rr_obstetric_fistula_obstructed_labour

relative risk of obstetric fistula in women who experienced obstructed labour

List

[14.8, 14.8]

prevalence_type_of_fistula

prevalence of 1.) vesicovaginal 2.)rectovaginal fistula

List

[[0.924, 0.076], [0.924, 0.076]]

prob_secondary_pph

baseline probability of secondary PPH

List

[0.0002, 0.00034]

rr_secondary_pph_endometritis

relative risk of secondary postpartum haemorrhage in women with sepsis secondary to endometritis

List

[1, 1]

prob_secondary_pph_severity

probability of mild, moderate or severe secondary PPH

List

[[0.33, 0.33, 0.34], [0.33, 0.33, 0.34]]

cfr_secondary_postpartum_haemorrhage

case fatality rate for secondary pph

List

[0.22, 0.08]

prob_htn_resolves

Weekly probability of resolution of hypertension

List

[0.167, 0.167]

weekly_prob_gest_htn_pn

weekly probability of a woman developing gestational hypertension during the postnatal period

List

[0.0025, 0.0025]

rr_gest_htn_obesity

Relative risk of gestational hypertension for women who are obese

List

[3.31, 3.31]

weekly_prob_pre_eclampsia_pn

weekly probability of a woman developing mild pre-eclampsia during the postnatal period

List

[0.0017, 0.0017]

rr_pre_eclampsia_obesity

Relative risk of pre-eclampsia for women who are obese

List

[3.2, 3.2]

rr_pre_eclampsia_chronic_htn

Relative risk of pre-eclampsia in women who are chronically hypertensive

List

[2.26, 2.26]

rr_pre_eclampsia_diabetes_mellitus

Relative risk of pre-eclampsia in women who have diabetes mellitus

List

[3.7, 3.7]

probs_for_mgh_matrix_pn

probability of mild gestational hypertension moving between states: gestational hypertension, severe gestational hypertension, mild pre-eclampsia, severe pre-eclampsia, eclampsia

List

[[0.918, 0.032, 0.05, 0, 0], [0.918, 0.032, 0.05, 0, 0]]

probs_for_sgh_matrix_pn

probability of severe gestational hypertension moving between states: gestational hypertension, severe gestational hypertension, mild pre-eclampsia, severe pre-eclampsia, eclampsia

List

[[0, 0.92, 0, 0.08, 0], [0, 0.92, 0, 0.08, 0]]

probs_for_mpe_matrix_pn

probability of mild pre-eclampsia moving between states: gestational hypertension, severe gestational hypertension, mild pre-eclampsia, severe pre-eclampsia, eclampsia

List

[[0, 0, 0.95, 0.05, 0], [0, 0, 0.95, 0.05, 0]]

probs_for_spe_matrix_pn

probability of severe pre-eclampsia moving between states: gestational hypertension, severe gestational hypertension, mild pre-eclampsia, severe pre-eclampsia, eclampsia

List

[[0, 0, 0, 0.95, 0.05], [0, 0, 0, 0.95, 0.05]]

probs_for_ec_matrix_pn

probability of eclampsia moving between states: gestational hypertension, severe gestational hypertension, mild pre-eclampsia, severe pre-eclampsia, eclampsia

List

[[0, 0, 0, 0, 1], [0, 0, 0, 0, 1]]

cfr_eclampsia

case fatality rate of eclampsia in the postnatal period

List

[0.028, 0.03]

cfr_severe_pre_eclampsia

case fatality rate of severe pre-eclampsia in the postnatal period

List

[0.018, 0.018]

weekly_prob_death_severe_gest_htn

weekly risk of death from severe hypertension in the postnatal period

List

[2e-05, 2e-05]

baseline_prob_anaemia_per_week

Weekly probability of anaemia in pregnancy

List

[0.017, 0.024]

rr_anaemia_maternal_malaria

relative risk of anaemia secondary to malaria infection

List

[1.45, 1.45]

rr_anaemia_recent_haemorrhage

relative risk of anaemia secondary to recent haemorrhage

List

[1.93, 1.93]

rr_anaemia_hiv_no_art

relative risk of anaemia for a woman with HIV not on ART

List

[4.19, 4.19]

prob_type_of_anaemia_pn

probability of a woman with anaemia having mild, moderate or severe anaemia

List

[[0.52, 0.475, 0.005], [0.52, 0.475, 0.005]]

prob_late_sepsis_endometritis

probability of developing sepsis following postpartum endometritis infection

List

[6.9e-05, 6.2e-05]

rr_sepsis_endometritis_post_cs

relative risk of endometritis following caesarean delivery

List

[12.1, 12.1]

prob_late_sepsis_urinary_tract

probability of developing sepsis following postpartum UTI

List

[5.4e-05, 5.4e-05]

prob_late_sepsis_skin_soft_tissue

probability of developing sepsis following postpartum skin/soft tissue infection

List

[3.9e-05, 3.5e-05]

rr_sepsis_sst_post_cs

relative risk of skin/soft tissue sepsis following caesarean delivery

List

[3.9, 3.9]

cfr_postpartum_sepsis

case fatality rate for postnatal sepsis

List

[0.75, 0.49]

prob_early_onset_neonatal_sepsis_week_1

Baseline probability of a newborn developing sepsis in week one of life

List

[0.02, 0.017]

rr_eons_maternal_chorio

relative risk of EONS in newborns whose mothers have chorioamnionitis

List

[6.6, 6.6]

rr_eons_maternal_prom

relative risk of EONS in newborns whose mothers have PROM

List

[4.9, 4.9]

rr_eons_preterm_neonate

relative risk of EONS in preterm newborns

List

[3.36, 3.36]

cfr_early_onset_neonatal_sepsis

case fatality for early onset neonatal sepsis

List

[0.064, 0.056]

prob_late_onset_neonatal_sepsis

probability of late onset neonatal sepsis (all cause)

List

[0.0045, 0.0038]

cfr_late_neonatal_sepsis

Risk of death from late neonatal sepsis

List

[0.064, 0.056]

prob_sepsis_disabilities

Probabilities of varying disability levels after neonatal sepsis

List

[[0.4, 0.1, 0.3, 0.1, 0.1], [0.4, 0.1, 0.3, 0.1, 0.1]]

prob_care_seeking_postnatal_emergency

baseline probability of emergency care seeking for women in the postnatal period

List

[0.782, 0.782]

prob_care_seeking_postnatal_emergency_neonate

baseline probability care will be sought for a neonate with a complication

List

[0.782, 0.782]

odds_care_seeking_fistula_repair

odds of a woman seeking care for treatment of obstetric fistula

List

[1.5, 1.5]

aor_cs_fistula_age_15_19

odds ratio for care seeking for treatment of obstetric fistula in 15-19 year olds

List

[0.31, 0.31]

aor_cs_fistula_age_lowest_education

odds ratio for care seeking for treatment of obstetric fistula in women in the lowest education quantile

List

[0.69, 0.69]

treatment_effect_early_init_bf

effect of early initiation of breastfeeding on neonatal sepsis rates

List

[0.55, 0.55]

treatment_effect_iron_folic_acid_anaemia

effect of iron and folic acid supplementation on anaemia risk

List

[0.3, 0.3]

treatment_effect_abx_prom

effect of early antibiotics given to a mother with PROM on neonatal sepsis rates

List

[0.67, 0.67]

treatment_effect_clean_birth

Treatment effect of clean birth practices on early onset neonatal sepsis risk

List

[0.73, 0.73]

treatment_effect_cord_care

Treatment effect of chlorhexidine cord care on early onset neonatal sepsis risk

List

[0.77, 0.77]

treatment_effect_anti_htns_progression_pn

Treatment effect of oral anti hypertensives on progression from mild/mod to severe gestationalhypertension

List

[0.49, 0.49]

PregnancySupervisor

Name

Description

Type

Value

prob_ectopic_pregnancy

probability of ectopic pregnancy

List

[0.01, 0.01]

prob_care_seeking_ectopic_pre_rupture

probability a woman will seek care for ectopic pregnancy prior to rupture

List

[0.08, 0.08]

prob_ectopic_pregnancy_death

probability of a woman dying from a ruptured ectopic pregnancy

List

[0.02, 0.012]

prob_multiples

probability that a woman is currently carrying more than one pregnancy

List

[0.0399, 0.0399]

prob_placenta_praevia

probability that this womans pregnancy will be complicated by placenta praevia

List

[0.005, 0.0058]

rr_placenta_praevia_previous_cs

relative risk of placenta praevia in a woman who has previously delivered via caesarean section

List

[1.47, 1.47]

prob_syphilis_during_pregnancy

probability that this womans will develop syphilis during her pregnancy

List

[0.028, 0.028]

prob_previous_miscarriage_at_baseline

probability that a woman at baseline will have previously experienced a miscarriage

Real

0.047

prob_spontaneous_abortion_per_month

underlying risk of spontaneous abortion per month

List

[[0.025, 0.037, 0.05, 0.037, 0.025], [0.025, 0.037, 0.05, 0.037, 0.025]]

rr_spont_abortion_age_35

relative risk of spontaneous abortion in women aged 35 years or older

List

[4, 4]

rr_spont_abortion_age_31_34

relative risk of spontaneous abortion in women aged 31-34 years old

List

[2.31, 2.31]

rr_spont_abortion_prev_sa

relative risk of spontaneous abortion in women who have previously experiences spontaneous abortion

List

[2.23, 2.23]

prob_complicated_sa

probability that a woman who experiences spontaneous abortion with experience any complications

List

[0.11, 0.11]

prob_induced_abortion_per_month

underlying risk of induced abortion per month

List

[0.038, 0.038]

prob_complicated_ia

probability that a woman who experiences induced abortion with experience any complications

List

[0.37, 0.37]

prob_haemorrhage_post_abortion

probability of haemorrhage following an abortion

List

[0.23, 0.23]

prob_sepsis_post_abortion

probability of sepsis following an abortion

List

[0.137, 0.137]

prob_injury_post_abortion

probability of injury following an abortion

List

[0.056, 0.056]

prob_induced_abortion_death

underlying risk of death following an induced abortion

List

[0.005, 0.0025]

prob_spontaneous_abortion_death

underlying risk of death following an spontaneous abortion

List

[0.01, 0.005]

baseline_prob_anaemia_per_month

baseline risk of a woman developing anaemia secondary only to pregnant

List

[0.1, 0.12]

rr_anaemia_maternal_malaria

relative risk of anaemia secondary to malaria infection

List

[1.45, 1.45]

rr_anaemia_hiv_no_art

relative risk of anaemia for a woman with HIV not on ART

List

[4.19, 4.19]

prob_mild_mod_sev_anaemia

probabilities that a womans anaemia will be mild, moderate or severe

List

[[0.52, 0.475, 0.005], [0.5, 0.46, 0.04]]

prob_gest_diab_per_month

underlying risk of gestational diabetes per month without the impact of risk factors

List

[0.0056, 0.0056]

rr_gest_diab_obesity

Relative risk of gestational diabetes for women who are obese

List

[3.97, 3.97]

prob_gest_htn_per_month

underlying risk of gestational hypertension per month without the impact of risk factors

List

[0.0073, 0.0073]

rr_gest_htn_obesity

Relative risk of gestational hypertension for women who are obese

List

[3.31, 3.31]

prob_pre_eclampsia_per_month

underlying risk of pre-eclampsia per month without the impact of risk factors

List

[0.0065, 0.0065]

rr_pre_eclampsia_obesity

Relative risk of pre-eclampsia for women who are obese

List

[3.2, 3.2]

rr_pre_eclampsia_multiple_pregnancy

Relative risk of pre-eclampsia for women who are pregnant with twins

List

[4.07, 4.07]

rr_pre_eclampsia_chronic_htn

Relative risk of pre-eclampsia in women who are chronically hypertensive

List

[2.26, 2.26]

rr_pre_eclampsia_diabetes_mellitus

Relative risk of pre-eclampsia in women who have diabetes mellitus

List

[3.7, 3.7]

probs_for_mgh_matrix

probability of mild gestational hypertension moving between states: gestational hypertension, severe gestational hypertension, mild pre-eclampsia, severe pre-eclampsia, eclampsia

List

[[0.918, 0.032, 0.05, 0, 0], [0.918, 0.032, 0.05, 0, 0]]

probs_for_sgh_matrix

probability of severe gestational hypertension moving between states: gestational hypertension, severe gestational hypertension, mild pre-eclampsia, severe pre-eclampsia, eclampsia

List

[[0, 0.87, 0, 0.13, 0], [0, 0.87, 0, 0.13, 0]]

probs_for_mpe_matrix

probability of mild pre-eclampsia moving between states: gestational hypertension, severe gestational hypertension, mild pre-eclampsia, severe pre-eclampsia, eclampsia

List

[[0, 0, 0.78, 0.22, 0], [0, 0, 0.78, 0.22, 0]]

probs_for_spe_matrix

probability of severe pre-eclampsia moving between states: gestational hypertension, severe gestational hypertension, mild pre-eclampsia, severe pre-eclampsia, eclampsia

List

[[0, 0, 0, 0.16, 0.84], [0, 0, 0, 0.16, 0.84]]

probs_for_ec_matrix

probability of eclampsia moving between states: gestational hypertension, severe gestational hypertension, mild pre-eclampsia, severe pre-eclampsia, eclampsia

List

[[0, 0, 0, 0, 1], [0, 0, 0, 0, 1]]

prob_severe_pre_eclampsia_death

probability of death for a woman experiencing acute severe pre-eclampsia

List

[0.018, 0.018]

prob_eclampsia_death

probability of death for a woman experiencing eclampsia

List

[0.028, 0.03]

prob_monthly_death_severe_htn

monthly risk of death for a woman with severe hypertension

List

[0.0001, 0.0001]

prob_placental_abruption_per_month

monthly probability that a woman will develop placental abruption

List

[0.0005, 0.0005]

rr_placental_abruption_hypertension

Relative risk of placental abruption in women with hypertension

List

[2.2, 2.2]

rr_placental_abruption_previous_cs

Relative risk of placental abruption in women who delivered previously via caesarean section

List

[1.3, 1.3]

prob_aph_placenta_praevia

risk of antepartum haemorrhage due to ongoing placenta praevia

List

[0.09, 0.09]

prob_aph_placental_abruption

risk of antepartum haemorrhage due to placental abruption

List

[0.9, 0.9]

prob_mod_sev_aph

probabilities that APH is mild/moderate or severe

List

[[0.8, 0.2], [0.8, 0.2]]

prob_antepartum_haemorrhage_death

probability of death for a woman suffering acute antepartum haemorrhage

List

[0.11, 0.04]

prob_prom_per_month

monthly probability that a woman will experience premature rupture of membranes

List

[0.0064, 0.0064]

prob_chorioamnionitis

monthly probability of a women developing chorioamnionitis

List

[0.015, 0.013]

prob_antenatal_sepsis_death

case fatality rate for chorioamnionitis

List

[0.75, 0.49]

baseline_prob_early_labour_onset

monthly baseline risk of labour onsetting before term

List

[[0.0008, 0.0033, 0.017, 0.04], [0.0008, 0.0033, 0.017, 0.04]]

rr_preterm_labour_post_prom

relative risk of early labour onset following PROM

List

[5.9, 5.9]

rr_preterm_labour_anaemia

relative risk of early labour onset in women with anaemia

List

[4.58, 4.58]

rr_preterm_labour_malaria

relative risk of early labour onset in women with malaria

List

[3.08, 3.08]

rr_preterm_labour_multiple_pregnancy

relative risk of early labour onset in women pregnant with twins

List

[3.44, 3.44]

prob_still_birth_per_month

underlying risk of stillbirth per month without the impact of risk factors

List

[0.0031, 0.0026]

rr_still_birth_ga_41

relative risk of still birth in women with gestational age 41 weeks

List

[2.24, 2.24]

rr_still_birth_ga_42

relative risk of still birth in women with gestational age 42 weeks

List

[3.88, 3.88]

rr_still_birth_ga_>42

relative risk of still birth in women with gestational age > 42 weeks

List

[6.94, 6.94]

rr_still_birth_gest_diab

relative risk of still birth in women with gestational diabetes

List

[3.91, 3.91]

rr_still_birth_diab_mellitus

relative risk of still birth in women with diabetes mellitus

List

[3.52, 3.52]

rr_still_birth_maternal_malaria

relative risk of still birth in women with malaria

List

[1.81, 1.81]

rr_still_birth_maternal_syphilis

relative risk of still birth in women with syphilis

List

[6.87, 6.87]

rr_still_birth_pre_eclampsia

relative risk of still birth in women with pre-eclampsia

List

[4.15, 4.15]

rr_still_birth_eclampsia

relative risk of still birth in women with eclampsia

List

[4.15, 4.15]

rr_still_birth_gest_htn

relative risk of still birth in women with mild gestational hypertension

List

[1.21, 1.21]

rr_still_birth_chronic_htn

relative risk of still birth in women with chronic hypertension

List

[2.32, 2.23]

rr_still_birth_aph

relative risk of still birth in women with antepartum haemorrhage

List

[2.1, 2.1]

rr_still_birth_chorio

relative risk of still birth in women with chorioamnionitis

List

[2, 2]

prob_seek_care_pregnancy_complication

Probability that a woman who is pregnant will seek care in the event of a complication

List

[0.782, 0.782]

prob_seek_care_pregnancy_loss

Probability that a woman who has developed complications post pregnancy loss will seek care

List

[0.782, 0.782]

prob_seek_care_induction

Probability that a woman who is post term will seek care for induction of labour

List

[0.2, 0.2]

prob_anc1_months_2_to_4

list of probabilities that a woman will attend her first ANC visit at either month 2, 3 or 4 of pregnancy

List

[[0.165, 0.165, 0.67], [0.165, 0.364, 0.471]]

prob_anc1_months_5_to_9

list of probabilities that a woman will attend her first ANC visit on months 5-10

List

[[0.345, 0.245, 0.28, 0.015, 0.015, 0.1], [0.41, 0.25, 0.21, 0.015, 0.015, 0.1]]

odds_early_init_anc4

probability of a woman undergoing 4 or more basic ANC visits with the first visit occurring prior or during month 4 of pregnancy (EANC4+)

List

[0.32, 0.58]

aor_early_anc4_20_24

adjusted odds ratio of EANC4+ in women aged 20-24

List

[1.26, 1.26]

aor_early_anc4_25_29

adjusted odds ratio of EANC4+ in women aged 25-29

List

[1.44, 1.44]

aor_early_anc4_30_34

adjusted odds ratio of EANC4+ in women aged 30-34

List

[1.49, 1.49]

aor_early_anc4_35_39

adjusted odds ratio of EANC4+ in women aged 35-39

List

[1.64, 1.64]

aor_early_anc4_40_44

adjusted odds ratio of EANC4+ in women aged 40-44

List

[1.51, 1.51]

aor_early_anc4_45_49

adjusted odds ratio of EANC4+ in women aged 45-49

List

[1.91, 1.91]

aor_early_anc4_2010

adjusted odds ratio of EANC4+ in 2010

List

[1.51, 1.51]

aor_early_anc4_2015

adjusted odds ratio of EANC4+ in 2015

List

[2.03, 2.03]

aor_early_anc4_parity_2_3

adjusted odds ratio of EANC4+ in women with a parity of 2-3

List

[0.74, 0.74]

aor_early_anc4_parity_4_5

adjusted odds ratio of EANC4+ in women with a parity of 4-5

List

[0.65, 0.65]

aor_early_anc4_parity_6+

adjusted odds ratio of EANC4+ in women with a parity of 6+

List

[0.61, 0.61]

aor_early_anc4_secondary_edu

adjusted odds ratio of EANC4+ in women with secondary education

List

[1.24, 1.24]

aor_early_anc4_tertiary_edu

adjusted odds ratio of EANC4+ in women with tertiary education

List

[2.64, 2.64]

aor_early_anc4_richest_wealth

adjusted odds ratio of EANC4+ in women in the richest wealth quintile

List

[1.32, 1.32]

prob_late_initiation_anc4

probability a woman will undertake 4 or more ANC visits with the first being after 4 months

List

[0.3, 0.29]

prob_early_initiation_anc_below4

probabilities a woman will attend fewer than 4 ANC visits but the first visit will occur before month 4

List

[0.115, 0.101]

prob_early_anc_at_facility_level_1_2

probabilities a woman will attend ANC 1 at facility levels 1 or 2

List

[[0.5, 0.5], [0.5, 0.5]]

treatment_effect_ectopic_pregnancy_treatment

Treatment effect of ectopic pregnancy case management

List

[0.1, 0.1]

treatment_effect_post_abortion_care

Treatment effect of post abortion care

List

[0.2, 0.2]

treatment_effect_iron_folic_acid_anaemia

relative effect of daily iron and folic acid treatment on risk of maternal anaemia

List

[0.3, 0.3]

treatment_effect_calcium_pre_eclamp

risk reduction of pre-eclampsia for women taking daily calcium supplementation

List

[0.45, 0.45]

treatment_effect_gest_htn_calcium

Effect of calcium supplementation on risk of developing gestational hypertension

List

[0.65, 0.65]

treatment_effect_anti_htns_progression

Effect of anti hypertensive medication in reducing the risk of progression from mild to severe hypertension

List

[0.49, 0.49]

prob_glycaemic_control_diet_exercise

probability a womans GDM is controlled by diet and exercise during the first month of treatment

List

[0.5, 0.5]

prob_glycaemic_control_orals

probability a womans GDM is controlled by oral anti-diabetics during the first month of treatment

List

[0.936, 0.936]

treatment_effect_gdm_case_management

Treatment effect of GDM case management on mothers risk of stillbirth

List

[0.9, 0.9]

treatment_effect_still_birth_food_sups

risk reduction of still birth for women receiving nutritional supplements

List

[0.6, 0.6]

anc_service_structure

stores type of ANC service being delivered in the model (anc4 or anc8) and is used in analysisscripts to change ANC structure

Integer

8

analysis_year

Year on which the pregnancy analysis event is scheduled to update any relevant parameters for analysis (1st day 1st month)

Integer

2023

ps_analysis_in_progress

Used within the pregnancy_helper_function to signify that analysis is currently being conducted

Boolean

False

alternative_anc_coverage

Signals within the analysis event that an alternative level of ANC coverage has been determined following the events run

Boolean

False

alternative_anc_quality

Signals within the analysis event that an alternative level of ANC quality has been determined following the events run

Boolean

False

anc_availability_odds

Target odds of early initiation of ANC4+ when analysis is being conducted - only applied ifalternative_anc_coverage is true

Real

9.0

anc_availability_probability

Target probability of quality/consumables when analysis is being conducted - only applied if alternative_anc_quality is true

Real

0.9

alternative_ip_anc_quality

Signals within the analysis event that an alternative level of inpatient ANC quality has been determined following the events run

Boolean

False

ip_anc_availability_probability

Target probability of quality/consumables when analysis is being conducted - only applied if alternative_ip_anc_quality is true

Real

0.9

sens_analysis_min

Signals within the analysis event and code that sensitivity analysis is being undertaken in which ANC is blocked from occurring

Boolean

False

sens_analysis_max

Signals within the analysis event and code that sensitivity analysis is being undertaken in which the maximum coverage of ANC is enforced

Boolean

False

ProstateCancer

Name

Description

Type

Value

init_prop_prostate_ca_stage

initial proportions in prostate cancer stages for men aged 35-49

List

[0.0001, 0.0001, 5e-05]

init_prop_urinary_symptoms_by_stage

initial proportions of those in prostate ca stages that have urinary symptoms

List

[0.3, 0.5, 0.7]

init_prop_pelvic_pain_symptoms_by_stage

initial proportions of those in prostate ca stages that have pelvic pain symptoms

List

[0.0, 0.3, 0.7]

init_prop_with_urinary_symptoms_diagnosed_prostate_ca_by_stage

initial proportions of people with prostate ca and urinary symptoms that have been diagnosed

List

[0.3, 0.4, 0.5]

init_prop_with_pelvic_pain_symptoms_diagnosed_prostate_ca_by_stage

initial proportions of people with prostate ca and pelvic pain symptoms that have been diagnosed

List

[0.3, 0.4, 0.5]

init_prop_treatment_status_prostate_ca

initial proportions of people with prostate ca that had received treatment

List

[0.1, 0.1, 0.1]

init_prob_palliative_care

initial probability of being under palliative care if at metastatic stage

Real

0.95

r_prostate_confined_prostate_ca_none

probabilty per 3 months of incident (prostate confined) prostate cancer amongst people with no prostate ca (men, age35-49)

Real

4e-05

rr_prostate_confined_prostate_ca_age5069

rate ratio for incident (prostate confined) prostate cancer amongst men aged 50-69

Real

2.0

rr_prostate_confined_prostate_ca_agege70

rate ratio for incident (prostate confined) prostate cancer amongst men aged ge 70

Real

4.0

r_local_ln_prostate_ca_prostate_confined

probabilty per 3 months of local lymph node involved prostate ca amongst people with prostate confined prostate ca

Real

0.15

rr_local_ln_prostate_ca_undergone_curative_treatment

rate ratio for local lymph node involved prostate ca for people with prostate confined prostate cadue to undergoing curative treatment

Real

0.1

r_metastatic_prostate_ca_local_ln

probabilty per 3 months of metastatic prostate cancer amongst people with local lymph nodeinvolved prostate ca

Real

0.15

rr_metastatic_prostate_ca_undergone_curative_treatment

rate ratio for metastatic prostate cancer stage 1 for people with lymph node involved prostate ca due toundergoing curative treatment

Real

0.2

r_death_metastatic_prostate_cancer

probabilty per 3 months of death from prostate cancer mongst people with metastatic prostate cancer

Real

0.2

r_urinary_symptoms_prostate_ca

rate of urinary symptoms if have prostate confined prostate ca

Real

0.05

rr_urinary_symptoms_local_ln_or_metastatic_prostate_cancer

rate ratio of urinary symptoms in a person with local lymph node or metastatuc prostate cancer compared with prostate confined prostate ca

Real

1.5

r_pelvic_pain_symptoms_local_ln_prostate_ca

rate of pelvic pain or numbness symptoms if have local lymph node involved prostate cancer

Real

0.05

rr_pelvic_pain_metastatic_prostate_cancer

rate ratio of pelvic pain or numbness in a person with metastatic prostate cancer compared with lymph node involved prostate cancer

Real

1.5

rp_prostate_cancer_age5069

stage-specific relative prevalence at baseline of prostate cancer for age 50-69

Real

2.0

rp_prostate_cancer_agege70

stage-specific relative prevalence at baseline of prostate cancer for age 70+

Real

4.0

sensitivity_of_psa_test_for_prostate_ca

sensitivity of psa test for prostate cancer

Real

0.9

sensitivity_of_biopsy_for_prostate_ca

sensitivity of biopsy for prostate cancer

Real

0.95

RTI

Name

Description

Type

Value

base_rate_injrti

Base rate of RTI per year

Real

0.00420322902234662

rr_injrti_age04

risk ratio of RTI in age 0-4 compared to base rate of RTI

Real

0.145533

rr_injrti_age59

risk ratio of RTI in age 5-9 compared to base rate of RTI

Real

0.551895

rr_injrti_age1017

risk ratio of RTI in age 10-17 compared to base rate of RTI

Real

0.967017

rr_injrti_age1829

risk ratio of RTI in age 18-29 compared to base rate of RTI

Real

1.184184

rr_injrti_age3039

risk ratio of RTI in age 30-39 compared to base rate of RTI

Real

1.052843

rr_injrti_age4049

risk ratio of RTI in age 40-49 compared to base rate of RTI

Real

1.074376

rr_injrti_age5059

risk ratio of RTI in age 50-59 compared to base rate of RTI

Real

1.336449

rr_injrti_age6069

risk ratio of RTI in age 60-69 compared to base rate of RTI

Real

2.308514

rr_injrti_age7079

risk ratio of RTI in age 70-79 compared to base rate of RTI

Real

4.031226

rr_injrti_male

risk ratio of RTI when male compared to females

Real

2.7

rr_injrti_excessalcohol

risk ratio of RTI in those that consume excess alcohol compared to those who do not

Real

6.53

imm_death_proportion_rti

Proportion of those involved in an RTI that die at site of accident or die before seeking medical intervention

Real

0.007

prob_bleeding_leads_to_shock

The proportion of those with heavily bleeding injuries who go into shock

Real

0.042222

prob_death_iss_less_than_9

Proportion of people who pass away in the following month after medical treatment for injuries with an ISSscore less than or equal to 9

Real

0.00733191462346883

prob_death_iss_10_15

Proportion of people who pass away in the following month after medical treatment for injuries with an ISSscore from 10 to 15

Real

0.0111021545889758

prob_death_iss_16_24

Proportion of people who pass away in the following month after medical treatment for injuries with an ISSscore from 16 to 24

Real

0.0313608577284893

prob_death_iss_25_35

Proportion of people who pass away in the following month after medical treatment for injuries with an ISSscore from 25 to 34

Real

0.133987145668097

prob_death_iss_35_plus

Proportion of people who pass away in the following month after medical treatment for injuries with an ISSscore 35 and above

Real

0.22782740761579

prob_perm_disability_with_treatment_severe_TBI

probability that someone with a treated severe TBI is permanently disabled

Real

0.199

prob_death_TBI_SCI_no_treatment

probability that someone with a spinal cord injury will die without treatment

Real

0.9

prop_death_burns_no_treatment

probability that someone with a burn injury will die without treatment

Real

0.6

prob_death_fractures_no_treatment

probability that someone with a fracture injury will die without treatment

Real

0.1

prob_TBI_require_craniotomy

probability that someone with a traumatic brain injury will require a craniotomy surgery

Real

0.124

prob_exploratory_laparotomy

probability that someone with an internal organ injury will require a exploratory_laparotomy

Real

0.319

prob_depressed_skull_fracture

Probability that a skull fracture will be depressed and therefore require surgery

Real

0.14

prob_mild_burns

Probability that a burn within a region will result in < 10% total body surface area

Real

0.56

prob_dislocation_requires_surgery

Probability that a dislocation will require surgery to relocate the joint.

Real

0.01

number_of_injured_body_regions_distribution

The distribution of number of injured AIS body regions, used to decide how many injuries a person has

List

[[1, 2, 3, 4, 5, 6, 7, 8], [0.7362050184224718, 0.19421990546958515, 0.051237591074077896, 0.013517104401461814, 0.0035659777825202245, 0.0009407486372638106, 0.0002481810186400668, 6.547319397917849e-05]]

injury_location_distribution

The distribution of where injuries are located in the body, based on the AIS body region definition

List

[[1, 2, 3, 4, 5, 6, 7, 8], [0.1438, 0.1325, 0.021, 0.0945, 0.0612, 0.0155, 0.1685, 0.363]]

mean_los_ISS_less_than_4

Mean length of stay for someone with an ISS score < 4

Real

4.97

sd_los_ISS_less_than_4

Standard deviation in length of stay for someone with an ISS score < 4

Real

4.86

mean_los_ISS_4_to_8

Mean length of stay for someone with an ISS score between 4 and 8

Real

8.91

sd_los_ISS_4_to_8

Standard deviation in length of stay for someone with an ISS score between 4 and 8

Real

5.93

mean_los_ISS_9_to_15

Mean length of stay for someone with an ISS score between 9 and 15

Real

15.46

sd_los_ISS_9_to_15

Standard deviation in length of stay for someone with an ISS score between 9 and 15

Real

11.16

mean_los_ISS_16_to_24

Mean length of stay for someone with an ISS score between 16 and 24

Real

24.73

sd_los_ISS_16_to_24

Standard deviation in length of stay for someone with an ISS score between 16 and 24

Real

17.03

mean_los_ISS_more_than_25

Mean length of stay for someone with an ISS score between 16 and 24

Real

30.86

sd_los_ISS_more_that_25

Standard deviation in length of stay for someone with an ISS score between 16 and 24

Real

34.03

daly_wt_unspecified_skull_fracture

daly_wt_unspecified_skull_fracture - code 1674

Real

0.195

daly_wt_basilar_skull_fracture

daly_wt_basilar_skull_fracture - code 1675

Real

0.149

daly_wt_epidural_hematoma

daly_wt_epidural_hematoma - code 1676

Real

0.185

daly_wt_subdural_hematoma

daly_wt_subdural_hematoma - code 1677

Real

0.21

daly_wt_subarachnoid_hematoma

daly_wt_subarachnoid_hematoma - code 1678

Real

0.214

daly_wt_brain_contusion

daly_wt_brain_contusion - code 1679

Real

0.174

daly_wt_intraventricular_haemorrhage

daly_wt_intraventricular_haemorrhage - code 1680

Real

0.174

daly_wt_diffuse_axonal_injury

daly_wt_diffuse_axonal_injury - code 1681

Real

0.239

daly_wt_subgaleal_hematoma

daly_wt_subgaleal_hematoma - code 1682

Real

0.174

daly_wt_midline_shift

daly_wt_midline_shift - code 1683

Real

0.239

daly_wt_facial_fracture

daly_wt_facial_fracture - code 1684

Real

0.067

daly_wt_facial_soft_tissue_injury

daly_wt_facial_soft_tissue_injury - code 1685

Real

0.008

daly_wt_eye_injury

daly_wt_eye_injury - code 1686

Real

0.054

daly_wt_neck_soft_tissue_injury

daly_wt_neck_soft_tissue_injury - code 1687

Real

0.1

daly_wt_neck_internal_bleeding

daly_wt_neck_internal_bleeding - code 1688

Real

0.1

daly_wt_neck_dislocation

daly_wt_neck_dislocation - code 1689

Real

0.187

daly_wt_chest_wall_bruises_hematoma

daly_wt_chest_wall_bruises_hematoma - code 1690

Real

0.143

daly_wt_hemothorax

daly_wt_hemothorax - code 1691

Real

0.143

daly_wt_lung_contusion

daly_wt_lung_contusion - code 1692

Real

0.205

daly_wt_diaphragm_rupture

daly_wt_diaphragm_rupture - code 1693

Real

0.205

daly_wt_rib_fracture

daly_wt_rib_fracture - code 1694

Real

0.187

daly_wt_flail_chest

daly_wt_flail_chest - code 1695

Real

0.211

daly_wt_chest_wall_laceration

daly_wt_chest_wall_laceration - code 1696

Real

0.143

daly_wt_closed_pneumothorax

daly_wt_closed_pneumothorax - code 1697

Real

0.164

daly_wt_open_pneumothorax

daly_wt_open_pneumothorax - code 1698

Real

0.164

daly_wt_surgical_emphysema

daly_wt_surgical_emphysema aka subcuteal emphysema - code 1699

Real

0.164

daly_wt_abd_internal_organ_injury

daly_wt_abd_internal_organ_injury - code 1700

Real

0.182

daly_wt_spinal_cord_lesion_neck_with_treatment

daly_wt_spinal_cord_lesion_neck_with_treatment - code 1701

Real

0.589

daly_wt_spinal_cord_lesion_neck_without_treatment

daly_wt_spinal_cord_lesion_neck_without_treatment - code 1702

Real

0.732

daly_wt_spinal_cord_lesion_below_neck_with_treatment

daly_wt_spinal_cord_lesion_below_neck_with_treatment - code 1703

Real

0.296

daly_wt_spinal_cord_lesion_below_neck_without_treatment

daly_wt_spinal_cord_lesion_below_neck_without_treatment - code 1704

Real

0.623

daly_wt_vertebrae_fracture

daly_wt_vertebrae_fracture - code 1705

Real

0.111

daly_wt_clavicle_scapula_humerus_fracture

daly_wt_clavicle_scapula_humerus_fracture - code 1706

Real

0.035

daly_wt_hand_wrist_fracture_with_treatment

daly_wt_hand_wrist_fracture_with_treatment - code 1707

Real

0.01

daly_wt_hand_wrist_fracture_without_treatment

daly_wt_hand_wrist_fracture_without_treatment - code 1708

Real

0.014

daly_wt_radius_ulna_fracture_short_term_with_without_treatment

daly_wt_radius_ulna_fracture_short_term_with_without_treatment - code 1709

Real

0.028

daly_wt_radius_ulna_fracture_long_term_without_treatment

daly_wt_radius_ulna_fracture_long_term_without_treatment - code 1710

Real

0.043

daly_wt_dislocated_shoulder

daly_wt_dislocated_shoulder - code 1711

Real

0.062

daly_wt_amputated_finger

daly_wt_amputated_finger - code 1712

Real

0.005

daly_wt_amputated_thumb

daly_wt_amputated_thumb - code 1713

Real

0.011

daly_wt_unilateral_arm_amputation_with_treatment

daly_wt_unilateral_arm_amputation_with_treatment - code 1714

Real

0.039

daly_wt_unilateral_arm_amputation_without_treatment

daly_wt_unilateral_arm_amputation_without_treatment - code 1715

Real

0.118

daly_wt_bilateral_arm_amputation_with_treatment

daly_wt_bilateral_arm_amputation_with_treatment - code 1716

Real

0.123

daly_wt_bilateral_arm_amputation_without_treatment

daly_wt_bilateral_arm_amputation_without_treatment - code 1717

Real

0.383

daly_wt_foot_fracture_short_term_with_without_treatment

daly_wt_foot_fracture_short_term_with_without_treatment - code 1718

Real

0.026

daly_wt_foot_fracture_long_term_without_treatment

daly_wt_foot_fracture_long_term_without_treatment - code 1719

Real

0.026

daly_wt_patella_tibia_fibula_fracture_with_treatment

daly_wt_patella_tibia_fibula_fracture_with_treatment - code 1720

Real

0.05

daly_wt_patella_tibia_fibula_fracture_without_treatment

daly_wt_patella_tibia_fibula_fracture_without_treatment - code 1721

Real

0.055

daly_wt_hip_fracture_short_term_with_without_treatment

daly_wt_hip_fracture_short_term_with_without_treatment - code 1722

Real

0.258

daly_wt_hip_fracture_long_term_with_treatment

daly_wt_hip_fracture_long_term_with_treatment - code 1723

Real

0.058

daly_wt_hip_fracture_long_term_without_treatment

daly_wt_hip_fracture_long_term_without_treatment - code 1724

Real

0.402

daly_wt_pelvis_fracture_short_term

daly_wt_pelvis_fracture_short_term - code 1725

Real

0.279

daly_wt_pelvis_fracture_long_term

daly_wt_pelvis_fracture_long_term - code 1726

Real

0.182

daly_wt_femur_fracture_short_term

daly_wt_femur_fracture_short_term - code 1727

Real

0.111

daly_wt_femur_fracture_long_term_without_treatment

daly_wt_femur_fracture_long_term_without_treatment - code 1728

Real

0.042

daly_wt_dislocated_hip

daly_wt_dislocated_hip - code 1729

Real

0.016

daly_wt_dislocated_knee

daly_wt_dislocated_knee - code 1730

Real

0.113

daly_wt_amputated_toes

daly_wt_amputated_toes - code 1731

Real

0.006

daly_wt_unilateral_lower_limb_amputation_with_treatment

daly_wt_unilateral_lower_limb_amputation_with_treatment - code 1732

Real

0.039

daly_wt_unilateral_lower_limb_amputation_without_treatment

daly_wt_unilateral_lower_limb_amputation_without_treatment - code 1733

Real

0.173

daly_wt_bilateral_lower_limb_amputation_with_treatment

daly_wt_bilateral_lower_limb_amputation_with_treatment - code 1734

Real

0.088

daly_wt_bilateral_lower_limb_amputation_without_treatment

daly_wt_bilateral_lower_limb_amputation_without_treatment - code 1735

Real

0.443

rt_emergency_care_ISS_score_cut_off

A parameter to determine which level of injury severity corresponds to the emergency health care seeking symptom and which to the non-emergency generic injury symptom

Integer

5

prob_death_MAIS3

A parameter to determine the probability of death without medical intervention with a military AISscore of 3

Real

0.05

prob_death_MAIS4

A parameter to determine the probability of death without medical intervention with a military AISscore of 4

Real

0.31

prob_death_MAIS5

A parameter to determine the probability of death without medical intervention with a military AISscore of 5

Real

0.59

prob_death_MAIS6

A parameter to determine the probability of death without medical intervention with a military AISscore of 6

Real

0.83

femur_fracture_skeletal_traction_mean_los

The mean length of stay for a person with a femur fracture being treated with skeletal traction

Integer

52

other_skeletal_traction_los

The mean length of stay for a person with a non-femur fracture being treated with skeletal traction

Integer

42

prob_foot_frac_require_cast

The probability that a person with a foot fracture will be treated with a plaster cast

Real

0.613

prob_foot_frac_require_maj_surg

The probability that a person with a foot fracture will be treated with a major surgery

Real

0.263

prob_foot_frac_require_min_surg

The probability that a person with a foot fracture will be treated with a major surgery

Real

0.038

prob_foot_frac_require_amp

The probability that a person with a foot fracture will be treated with amputation via a major surgery

Real

0.086

prob_tib_fib_frac_require_cast

The probability that a person with a tibia/fibula fracture will be treated with a plaster cast

Real

0.71

prob_tib_fib_frac_require_maj_surg

The probability that a person with a tibia/fibula fracture will be treated with a major surgery

Real

0.066

prob_tib_fib_frac_require_min_surg

The probability that a person with a tibia/fibula fracture will be treated with a minor surgery

Real

0.175

prob_tib_fib_frac_require_amp

The probability that a person with a tibia/fibula fracture will be treated with an amputation via major surgery

Real

0.024

prob_tib_fib_frac_require_traction

The probability that a person with a tibia/fibula fracture will be treated with skeletal traction

Real

0.025

prob_femural_fracture_require_major_surgery

The probability that a person with a femur fracture will be treated with major surgery

Real

0.187

prob_femural_fracture_require_minor_surgery

The probability that a person with a femur fracture will be treated with minor surgery

Real

0.007

prob_femural_fracture_require_cast

The probability that a person with a femur fracture will be treated with a plaster cast

Real

0.024

prob_femural_fracture_require_amputation

The probability that a person with a femur fracture will be treated with amputation via major surgery

Real

0.005

prob_femural_fracture_require_traction

The probability that a person with a femur fracture will be treated with skeletal traction

Real

0.777

prob_pelvis_fracture_traction

The probability that a person with a pelvis fracture will be treated with skeletal traction

Real

0.71

prob_pelvis_frac_major_surgery

The probability that a person with a pelvis fracture will be treated with major surgery

Real

0.12

prob_pelvis_frac_minor_surgery

The probability that a person with a pelvis fracture will be treated with minor surgery

Real

0.05

prob_pelvis_frac_cast

The probability that a person with a pelvis fracture will be treated with a cast

Real

0.12

prob_dis_hip_require_maj_surg

The probability that a person with a dislocated hip will be treated with a major surgery

Real

0.167

prob_dis_hip_require_cast

The probability that a person with a dislocated hip will be treated with a plaster cast

Real

0.333

prob_hip_dis_require_traction

The probability that a person with a dislocated hip will be treated with skeletal traction

Real

0.5

hdu_cut_off_iss_score

The ISS score used as a criteria to admit patients to the HDU/ICU units

Integer

29

mean_icu_days

The mean length of stay in the ICUfor those without TBI

Real

4.8

sd_icu_days

The standard deviation in length of stay in the ICU for those without TBI

Real

6.0

mean_tbi_icu_days

The mean length of stay in the ICU for those with TBI

Real

8.4

sd_tbi_icu_days

The standard deviation in length of stay in the ICU for those with TBI

Real

6.4

prob_open_fracture_contaminated

The probability that an open fracture will be contaminated

Real

0.07

allowed_interventions

List of additional interventions that can be included when performing model analysis

List

[]

head_prob_112

The probability that this person’s head injury is a skull fracture

Real

0.0455

head_prob_113

The probability that this person’s head injury is a basilar skull fracture

Real

0.0045

head_prob_133a

The probability that this person’s head injury is a Subarachnoid hematoma

Real

0.09149906

head_prob_133b

The probability that this person’s head injury is a Brain contusion

Real

0.301946898

head_prob_133c

The probability that this person’s head injury is an Intraventricular haemorrhage

Real

0.013724859

head_prob_133d

The probability that this person’s head injury is a Subgaleal hematoma

Real

0.050324483

head_prob_134a

The probability that this person’s head injury is an Epidural hematoma

Real

0.086670324

head_prob_134b

The probability that this person’s head injury is a Subdural hematoma

Real

0.080003376

head_prob_135

The probability that this person’s head injury is a Diffuse axonal injury/midline shift

Real

0.061731

head_prob_1101

The probability that this person’s head injury is a laceration

Real

0.253536

head_prob_1114

The probability that this person’s head injury is a burn

Real

0.010564

face_prob_211

The probability that this person’s face injury is a Facial fracture (nasal/unspecified)

Real

0.158585

face_prob_212

The probability that this person’s face injury is a Facial fracture (mandible/zygomatic)

Real

0.294515

face_prob_241

The probability that this person’s face injury is a soft tissue injury

Real

0.339

face_prob_2101

The probability that this person’s face injury is a laceration

Real

0.194845

face_prob_2114

The probability that this person’s face injury is a burn

Real

0.010255

face_prob_291

The probability that this person’s face injury is an eye injury

Real

0.0028

neck_prob_3101

The probability that this person’s neck injury is a laceration

Real

0.06972

neck_prob_3113

The probability that this person’s neck injury is a burn

Real

0.01428

neck_prob_342

The probability that this person’s neck injury is a Soft tissue injury in neck (vertebral artery laceration)

Real

0.004

neck_prob_343

The probability that this person’s neck injury is a Soft tissue injury in neck (pharynx contusion)

Real

0.004

neck_prob_361

The probability that this person’s neck injury is a Sternomastoid m. hemorrhage/ Hemorrhage, supraclavicular triangle/Hemorrhage, posterior triangle/Anterior vertebral vessel hemorrhage/ Neck muscle hemorrhage

Real

0.495

neck_prob_363

The probability that this person’s neck injury is a Hematoma in carotid sheath/Carotid sheath hemorrhage

Real

0.405

neck_prob_322

The probability that this person’s neck injury is an Atlanto-occipital subluxation

Real

0.00264

neck_prob_323

The probability that this person’s neck injury is an Atlanto-axial subluxation

Real

0.00536

thorax_prob_4101

The probability that this person’s thorax injury is a laceration

Real

0.49036

thorax_prob_4113

The probability that this person’s thorax injury is a burn

Real

0.04264

thorax_prob_461

The probability that this person’s thorax injury is Chest wall bruises/haematoma

Real

0.0945

thorax_prob_463

The probability that this person’s thorax injury is Haemothorax

Real

0.0945

thorax_prob_453a

The probability that this person’s thorax injury is a Lung contusion

Real

0.0539

thorax_prob_453b

The probability that this person’s thorax injury is a Diaphragm rupture

Real

0.0161

thorax_prob_412

The probability that this person’s thorax injury is a rib fracture

Real

0.0392

thorax_prob_414

The probability that this person’s thorax injury is flail chest

Real

0.0098

thorax_prob_441

The probability that this person’s thorax injury is a Chest wall lacerations/avulsions

Real

0.08586

thorax_prob_442

The probability that this person’s thorax injury is a Surgical emphysema

Real

0.01749

thorax_prob_443

The probability that this person’s thorax injury is a Closed pneumothorax/ open pneumothorax

Real

0.05565

abdomen_prob_5101

The probability that this person’s abdomen injury is a laceration

Real

0.11026

abdomen_prob_5113

The probability that this person’s thorax injury is a burn

Real

0.03874

abdomen_prob_552

The probability that this person’s thorax injury is a skull fracture

Real

0.047656

abdomen_prob_553

The probability that this person’s thorax injury is an Injury to stomach/intestines/colon

Real

0.77441

abdomen_prob_554

The probability that this person’s thorax injury is an Injury to spleen/Urinary bladder/Liver/Urethra/Diaphragm

Real

0.028934

spine_prob_612

The probability that this person’s spine injury is a vertabrae fracture

Real

0.364

spine_prob_673a

The probability that this person’s spine injury is a Spinal cord injury at neck level

Real

0.015840216

spine_prob_673b

The probability that this person’s spine injury is a Spinal cord injury below neck level

Real

0.040731984

spine_prob_674a

The probability that this person’s spine injury is a Spinal cord injury at neck level

Real

0.074477731

spine_prob_674b

The probability that this person’s spine injury is a Spinal cord injury below neck level

Real

0.116490809

spine_prob_675a

The probability that this person’s spine injury is a Spinal cord injury at neck level

Real

0.134791137

spine_prob_675b

The probability that this person’s spine injury is a Spinal cord injury below neck level

Real

0.210827163

spine_prob_676

The probability that this person’s spine injury is a Spinal cord injury at neck level

Real

0.04284096

upper_ex_prob_7101

The probability that this person’s upper extremity injury is a laceration

Real

0.43896

upper_ex_prob_7113

The probability that this person’s upper extremity injury is a burn

Real

0.03304

upper_ex_prob_712a

The probability that this person’s upper extremity injury is a Fracture to Clavicle, scapula, humerus

Real

0.10802

upper_ex_prob_712b

The probability that this person’s upper extremity injury is a Fracture to Hand/wrist

Real

0.28969

upper_ex_prob_712c

The probability that this person’s upper extremity injury is a Fracture to Radius/ulna

Real

0.09329

upper_ex_prob_722

The probability that this person’s upper extremity injury is a dislocated shoulder

Real

0.025

upper_ex_prob_782a

The probability that this person’s upper extremity injury is an Amputated finger

Real

0.00750024

upper_ex_prob_782b

The probability that this person’s upper extremity injury is a Unilateral arm amputation

Real

0.00102276

upper_ex_prob_782c

The probability that this person’s upper extremity injury is a Thumb amputation

Real

0.002841

upper_ex_prob_783

The probability that this person’s upper extremity injury is a bilateral arm amputation

Real

0.000636

lower_ex_prob_8101

The probability that this person’s lower extremity injury is a laceration

Real

0.186094109

lower_ex_prob_8113

The probability that this person’s lower extremity injury is a burn

Real

0.014007083

lower_ex_prob_811

The probability that this person’s lower extremity injury is a foot fracture

Real

0.023610948

lower_ex_prob_813do

The probability that this person’s lower extremity injury is an open foot fracture

Real

0.013281158

lower_ex_prob_812

The probability that this person’s lower extremity injury is a Fracture to patella, tibia, fibula, ankle

Real

0.354164215

lower_ex_prob_813eo

The probability that this person’s lower extremity injury is an open Fracture to patella, tibia, fibula, ankle

Real

0.199217371

lower_ex_prob_813a

The probability that this person’s lower extremity injury is a Hip fracture

Real

0.029513685

lower_ex_prob_813b

The probability that this person’s lower extremity injury is a Pelvis fracture

Real

0.023610948

lower_ex_prob_813bo

The probability that this person’s lower extremity injury is an open Pelvis fracture

Real

0.005902737

lower_ex_prob_813c

The probability that this person’s lower extremity injury is a Femur fracture

Real

0.076765094

lower_ex_prob_813co

The probability that this person’s lower extremity injury is an open Femur fracture

Real

0.01177596

lower_ex_prob_822a

The probability that this person’s lower extremity injury is a Dislocated hip

Real

0.037338982

lower_ex_prob_822b

The probability that this person’s lower extremity injury is a Dislocated knee

Real

0.002383339

lower_ex_prob_882

The probability that this person’s lower extremity injury is an Amputation of toes

Real

0.00731139

lower_ex_prob_883

The probability that this person’s lower extremity injury is a Unilateral leg amputation

Real

0.007511491

lower_ex_prob_884

The probability that this person’s lower extremity injury is a Bilateral leg amputation

Real

0.007511491

blocked_interventions

A list of interventions that are blocked in a simulation

List

[]

unavailable_treatment_mortality_mais_cutoff

A cut-off score above which an injury will result in additional mortality if the person has sought healthcare and not received it.

Integer

5

consider_death_no_treatment_ISS_cut_off

A cut-off score above which an injuries will be considered severe enough to cause mortality in those whohave not sought care.

Integer

15

maximum_number_of_times_HSI_events_should_run

limit on the number of times an HSI event can run

Integer

5

Schisto

Name

Description

Type

Value

prob_sent_to_lab_test_children

Probability that infected child gets sent to lab test

Real

0.9

prob_sent_to_lab_test_adults

Probability that an infected adults gets sent to lab test

Real

0.6

delay_till_hsi_a_repeated

Time till seeking healthcare again after not being sent to schisto test: start

Real

5.0

delay_till_hsi_b_repeated

Time till seeking healthcare again after not being sent to schisto test: end

Real

20.0

PZQ_efficacy

The efficacy of Praziquantel in clearing burden of any Schistosomiasis worm species

Real

1.0

MDA_coverage_historical

Probability of getting PZQ in the MDA for PSAC, SAC and Adults in historic rounds

Dataframe

MDA_coverage_prognosed

Probability of getting PZQ in the MDA for PSAC, SAC and Adults in future rounds, with the frequency given in months

Dataframe

sm_beta_PSAC

Contact/exposure rate of PSAC

Real

0.3

sm_beta_SAC

Contact/exposure rate of SAC

Real

1.0

sm_beta_Adults

Contact/exposure rate of Adults

Real

0.05

sm_worms_fecundity

Fecundity parameter, driving density-dependent reproduction

Real

0.0006

sm_worm_lifespan

Lifespan of the worm in human host given in years

Real

4.0

sm_high_intensity_threshold

Threshold of worm burden indicating high intensity infection

Real

46.0

sm_low_intensity_threshold

Threshold of worm burden indicating low intensity infection

Real

2.0

sm_high_intensity_threshold_PSAC

Worm burden threshold for high intensity infection in PSAC

Real

20.0

sm_reservoir_2010

Initial reservoir of infectious material per district in 2010

Series

sm_gamma_alpha

Parameter alpha for Gamma distribution for harbouring rates

Series

sm_R0

Effective reproduction number, for the FOI

Series

sh_beta_PSAC

Contact/exposure rate of PSAC

Real

0.3

sh_beta_SAC

Contact/exposure rate of SAC

Real

1.0

sh_beta_Adults

Contact/exposure rate of Adults

Real

0.05

sh_worms_fecundity

Fecundity parameter, driving density-dependent reproduction

Real

0.005

sh_worm_lifespan

Lifespan of the worm in human host given in years

Real

6.0

sh_high_intensity_threshold

Threshold of worm burden indicating high intensity infection

Real

20.0

sh_low_intensity_threshold

Threshold of worm burden indicating low intensity infection

Real

2.0

sh_high_intensity_threshold_PSAC

Worm burden threshold for high intensity infection in PSAC

Real

5.0

sh_reservoir_2010

Initial reservoir of infectious material per district in 2010

Series

sh_gamma_alpha

Parameter alpha for Gamma distribution for harbouring rates

Series

sh_R0

Effective reproduction number, for the FOI

Series

MDA_coverage_historical

PSAC

SAC

Adults

0

0.85

0.44

0

0.92

0.88

0

0.87

0.88

0

0.73

0.02

0

0.8

0.155

0

0.87

0.29

0

0.87

0.9

0

0.48

0.96

0

0.605

0.96

Only first 10 rows of 128 are shown.

MDA_coverage_prognosed

PSAC

SAC

Adults

0.5

0.8

0.5

0.5

0.8

0.5

0.5

0.8

0.5

0.5

0.8

0.5

0.5

0.8

0.5

0

0.8

0.5

0

0.8

0.5

0

0.8

0.5

0

0.8

0.5

Only first 10 rows of 32 are shown.

sm_reservoir_2010

Reservoir

0.0796066

0.0796066

0.0243277

0.158777

0

0

0

0.0891927

0

Only first 10 rows of 32 are shown.

sm_gamma_alpha

alpha_value

0.0652093

0.0652093

0.056

0.07445

0.05

0.05

0.05

0.0665

0.05

Only first 10 rows of 32 are shown.

sm_R0

R0_value

1.46175

1.46175

2.18968

1.26817

0

0

0

1.42196

0

Only first 10 rows of 32 are shown.

sh_reservoir_2010

Reservoir

1.87216

0

0

2.81222

0

0

0

0

0

Only first 10 rows of 32 are shown.

sh_gamma_alpha

alpha_value

0.107616

0.04664

0.0805

0.1377

0.08905

0.0698

0

0.0643

0.0793714

Only first 10 rows of 32 are shown.

sh_R0

R0_value

1.12956

1.1253

1.1248

1.14141

1.12577

1.12423

0

1.12421

1.12471

Only first 10 rows of 32 are shown.

Stunting

Name

Description

Type

Value

prev_HAZ_distribution_age_0_5mo

Distribution of HAZ among less than 6 months of age in 2015 (mean, standard deviation)

List

[-0.8482365, 1.416337]

prev_HAZ_distribution_age_6_11mo

Distribution of HAZ among 6 months and 1 year of age in 2015 (mean, standard deviation)

List

[-0.9940219, 1.504431]

prev_HAZ_distribution_age_12_23mo

Distribution of HAZ among 1 year olds in 2015 (mean, standard deviation)

List

[-1.522101, 1.431207]

prev_HAZ_distribution_age_24_35mo

Distribution of HAZ among 2 year olds in 2015 (mean, standard deviation)

List

[-1.669291, 1.343577]

prev_HAZ_distribution_age_36_47mo

Distribution of HAZ among 3 year olds in 2015 (mean, standard deviation)

List

[-1.797365, 1.212469]

prev_HAZ_distribution_age_48_59mo

Distribution of HAZ among 4 year olds in 2015 (mean, standard deviation)

List

[-1.620094, 1.11541]

or_stunting_male

Odds ratio of stunting if male gender

Real

1.38

or_stunting_preterm_and_AGA

Odds ratio of stunting if born preterm and adequate for gestational age

Real

2.13

or_stunting_SGA_and_term

Odds ratio of stunting if born term and small for geatational age

Real

2.36

or_stunting_SGA_and_preterm

Odds ratio of stunting if born preterm and small for gestational age

Real

5.95

or_stunting_hhwealth_Q5

Odds ratio of stunting if household wealth is poorest Q5, ref group Q1

Real

1.69

or_stunting_hhwealth_Q4

Odds ratio of stunting if household wealth is poorer Q4, ref group Q1

Real

1.48

or_stunting_hhwealth_Q3

Odds ratio of stunting if household wealth is middle Q3, ref group Q1

Real

1.4

or_stunting_hhwealth_Q2

Odds ratio of stunting if household wealth is richer Q2, ref group Q1

Real

1.29

base_inc_rate_stunting_by_agegp

Baseline incidence rate per year of stunting by age group (1-5, 6-11, 12-23, 24-35, 36-47, 48-59mo

List

[0.8, 0.8, 0.8, 0.8, 0.8, 0.8]

rr_stunting_preterm_and_AGA

Relative risk of stunting if born preterm and adequate for gestational age

Real

1.62

rr_stunting_SGA_and_term

Relative risk of stunting if born term and small for gestational age

Real

1.65

rr_stunting_SGA_and_preterm

Relative risk of stunting if born preterm and small for gestational age

Real

2.98

rr_stunting_prior_wasting

Relative risk of stunting if prior wasting in the last 3 months

Real

1.93

rr_stunting_untreated_HIV

Relative risk of stunting for untreated HIV+

Real

1.5

rr_stunting_wealth_level

Relative risk of stunting if wealth-level is greater than 1 compared 1

Real

0.2

rr_stunting_no_exclusive_breastfeeding

Relative risk of stunting for not exclusively breastfed babies < 6 months

Real

1.4

rr_stunting_no_continued_breastfeeding

Relative risk of stunting for not continued breastfed infants 6-24 months

Real

1.3

rr_stunting_per_diarrhoeal_episode

Relative risk of stunting for recent diarrhoea episode

Real

1.04

r_progression_severe_stunting_by_agegp

Rates per year of progression to severe stunting by age group (1-5, 6-11, 12-23, 24-35, 36-47, 48-59mo

List

[0.8, 0.8, 0.8, 0.8, 0.8, 0.8]

rr_progress_severe_stunting_if_prior_wasting

Relative risk of severe stunting if previously wasted

Real

1.93

rr_progress_severe_stunting_untreated_HIV

Relative risk of severe stunting for untreated HIV+

Real

1.3

mean_years_to_1stdev_natural_improvement_in_stunting

Mean time (in years) to a one standard deviation improvement in stunting without any treatment.

Real

1.840675229013975

effectiveness_of_complementary_feeding_education_in_stunting_reduction

Probability of stunting being reduced by one standard deviation (category) by education about supplementary feeding (but not supplying supplementary feeding consmables).

Real

0.25

effectiveness_of_food_supplementation_in_stunting_reduction

Probability of stunting being reduced by one standard deviation (category) by supplementary feeding.

Real

0.41

prob_stunting_diagnosed_at_generic_appt

Probability of a stunted or severely stunted person being checked and correctly diagnosed

Real

0.01

SymptomManager

Name

Description

Type

Value

generic_symptoms_spurious_occurrence

probability and duration of spurious occureneces of generic symptoms

Dataframe

spurious_symptoms

whether or not there will be the spontaneous occurrence of generic symptoms. NB. This is over-ridden if a module key-word argument is provided.

Boolean

True

generic_symptoms_spurious_occurrence

name

odds_ratio_health_seeking_in_children

odds_ratio_health_seeking_in_adults

prob_spurious_occurrence_in_children_per_day

prob_spurious_occurrence_in_adults_per_day

duration_in_days_of_spurious_occurrence_in_children

duration_in_days_of_spurious_occurrence_in_adults

prob_seeks_emergency_appt_in_adults

prob_seeks_emergency_appt_in_children

vomiting

1.31

0.48

0.001

0.001

7

4

0

0

stomachache

0.7

0.48

0.001

0.001

7

4

0

0

sore_throat

1.07

0.58

0.001

0.001

7

4

0

0

respiratory_symptoms

0.55

0.48

0.001

0.001

7

4

0

0

headache

0.39

0.28

0.001

0.001

7

4

0

0

skin_complaint

2.82

0.76

0.001

0.001

7

4

0

0

dental_complaint

0.39

0.92

0.001

0.001

7

4

0

0

backache

1

0.56

0.001

0.001

7

4

0

0

injury

0.55

0.68

0.001

0.001

7

4

0

0

Only first 10 rows of 13 are shown.

Tb

Name

Description

Type

Value

prop_mdr2010

Proportion of active tb cases with multidrug resistance in 2010

Real

0.0186

followup_times

times(weeks) tb treatment monitoring required after tx start

Dataframe

tb_high_risk_distr

list of ten high-risk districts

Dataframe

ipt_coverage

national estimates of coverage of IPT in PLHIV and paediatric contacts

Dataframe

rr_tb_child

relative risk of tb infection if under 16 years of age

Real

0.1

monthly_prob_relapse_tx_complete

monthly probability of relapse once treatment complete

Real

0.0027

monthly_prob_relapse_tx_incomplete

monthly probability of relapse if treatment incomplete

Real

0.0116

monthly_prob_relapse_2yrs

monthly probability of relapse 2 years after treatment complete

Real

0.0001

rr_relapse_hiv

relative risk of relapse for HIV-positive people

Real

4.7

rr_relapse_diabetes

relative risk of relapse for people with diabetes (treated/untreated)

Real

1.86

scaling_factor_WHO

scaling factor applied to WHO estimates to account for the impact of interventions in place

Real

1.60303

duration_active_disease_years

duration of active disease from onset to cure or death

Real

3.0

prop_smear_positive

proportion of new active cases that will be smear-positive

Real

0.62

prop_smear_positive_hiv

proportion of hiv+ active tb cases that will be smear-positive

Real

0.35

death_rate_smear_pos_untreated

probability of death in smear-positive tb cases with untreated tb

Real

0.7

death_rate_smear_neg_untreated

probability of death in smear-negative tb cases with untreated tb

Real

0.2

death_rate_child0_4_treated

probability of death in child aged 0-4 years with treated tb

Real

0.05

death_rate_child5_14_treated

probability of death in child aged 5-14 years with treated tb

Real

0.06

death_rate_adult_treated

probability of death in adult aged >=15 years with treated tb

Real

0.107

rr_death_diabetes

additional risk of death if person has diabetes (treated/untreated)

Real

1.51

rr_tb_bcg

relative risk of progression to active disease for children with BCG vaccine

Real

0.42

rr_tb_hiv

relative risk of progression to active disease for PLHIV

Real

5.0

rr_tb_aids

relative risk of progression to active disease for PLHIV with AIDS

Real

26.0

rr_tb_art_adult

relative risk of progression to active disease for adults with HIV on ART

Real

0.35

rr_tb_art_child

relative risk of progression to active disease for adults with HIV on ART

Real

0.3

rr_tb_obese

relative risk of progression to active disease if obese

Real

0.4

rr_tb_diabetes

relative risk of progression to active disease with any type diabetes

Real

3.0

rr_tb_alcohol

relative risk of progression to active disease with heavy alcohol use

Real

2.9

rr_tb_smoking

relative risk of progression to active disease with smoking

Real

1.3

rr_ipt_adult

relative risk of active TB with IPT in adults

Real

0.4

rr_ipt_child

relative risk of active TB with IPT in children

Real

0.55

rr_ipt_adult_hiv

relative risk of active TB with IPT in adults with hiv

Real

0.68

rr_ipt_child_hiv

relative risk of active TB with IPT in children with hiv

Real

0.31

rr_ipt_art_adult

relative risk of active TB with IPT and ART in adults

Real

0.63

rr_ipt_art_child

relative risk of active TB with IPT and ART in children

Real

0.76

sens_xpert_smear_negative

sensitivity of Xpert test in smear negative TB cases

Real

0.68

sens_xpert_smear_positive

sensitivity of Xpert test in smear positive TB cases

Real

0.98

spec_xpert_smear_negative

specificity of Xpert test in smear negative TB cases

Real

0.99

spec_xpert_smear_positive

specificity of Xpert test in smear positive TB cases

Real

0.99

sens_sputum_smear_positive

sensitivity of sputum smear microscopy in sputum positive cases

Real

1.0

spec_sputum_smear_positive

specificity of sputum smear microscopy in sputum positive cases

Real

1.0

sens_clinical

sensitivity of clinical diagnosis in detecting active TB

Real

0.209

spec_clinical

specificity of clinical diagnosis in detecting TB

Real

0.953

sens_xray_smear_negative

sensitivity of x-ray diagnosis in smear negative TB cases

Real

0.8

sens_xray_smear_positive

sensitivity of x-ray diagnosis in smear positive TB cases

Real

0.91

spec_xray_smear_negative

specificity of x-ray diagnosis in smear negative TB cases

Real

0.67

spec_xray_smear_positive

specificity of x-ray diagnosis in smear positive TB cases

Real

0.67

prob_tx_success_ds

Probability of treatment success for new and relapse TB cases

Real

0.837

prob_tx_success_mdr

Probability of treatment success for MDR-TB cases

Real

0.597

prob_tx_success_0_4

Probability of treatment success for children aged 0-4 years

Real

0.94

prob_tx_success_5_14

Probability of treatment success for children aged 5-14 years

Real

0.92

rate_testing_general_pop

rate of screening / testing per month in general population

Real

0.025

rate_testing_active_tb

rate of screening / testing per month in population with active tb

Dataframe

ds_treatment_length

length of treatment for drug-susceptible tb (first case) in months

Real

6.0

ds_retreatment_length

length of treatment for drug-susceptible tb (secondary case) in months

Real

8.0

mdr_treatment_length

length of treatment for mdr-tb in months

Real

24.0

prob_retained_ipt_6_months

probability of being retained on IPT every 6 months if still eligible

Real

0.9

age_eligibility_for_ipt

eligibility criteria (years of age) for IPT given to contacts of TB cases

Real

5.0

ipt_start_date

year from which IPT is available for paediatric contacts of diagnosed active TB cases

Integer

2014

first_line_test

name of first test to be used for TB diagnosis

String

sputum

second_line_test

name of second test to be used for TB diagnosis

String

xpert

tb_healthseekingbehaviour_cap

number of repeat visits assumed for healthcare services

Integer

5

data_end

last year for which data are available

Integer

2022

length_of_inpatient_stay_if_terminal

length of inpatient stay for end-of-life TB patients

List

[5, 10]

type_of_scaleup

argument to determine type scale-up of program which will be implemented, can be ‘none’, ‘target’ or ‘max’

String

none

scaleup_start_year

the year when the scale-up starts (it will occur on 1st January of that year)

Integer

2025

scaleup_parameters

the parameters and values changed in scenario analysis

Dataframe

followup_times

ds_sputum

ds_clinical_monitor

ds_retreatment_sputum

ds_retreatment_clinical

mdr_sputum

mdr_clinical_monitor

shine_sputum

shine_clinical_monitor

5

2

5

2

5

2

4

2

6

3

8

3

6

3

nan

3

nan

4

nan

4

8

4

nan

4

nan

5

nan

5

10

5

nan

nan

nan

6

nan

6

12

6

nan

nan

nan

nan

nan

7

14

7

nan

nan

nan

nan

nan

8

16

8

nan

nan

nan

nan

nan

nan

18

9

nan

nan

nan

nan

nan

nan

20

10

nan

nan

Only first 10 rows of 24 are shown.

tb_high_risk_distr

district_name

Blantyre

Blantyre City

Chikwawa

Chiradzulu

Chitipa

Dedza

Dowa

Karonga

Kasungu

Only first 10 rows of 32 are shown.

ipt_coverage

year

coverage_plhiv

source

coverage_paediatric

source2

2011

0

not_implemented

0

nan

2012

0

not_implemented

0

nan

2013

0

not_implemented

0

nan

2014

0

not_implemented

35

NTP2019

2015

0

not_implemented

42

NTP2019

2016

0

not_implemented

51

NTP2019

2017

0

not_implemented

61

NTP2019

2018

0.31

MoH_quart_repQ1

57

NTP2019

2019

0.3

MoH_quart_repQ2

57

NTP2020

Only first 10 rows of 41 are shown.

rate_testing_active_tb

year

case_notification_rate_per_100k

treatment_coverage

treatment_success_rates

death_rate

percent_hiv_positive

number_notified_mdr_cases

percent_mdr_treatment_success

percent_death_mdr_cases

coverage_ipt_paediatric_contacts

2011

nan

46

82.7

10.7

nan

nan

nan

nan

nan

2012

138

51

81.8

10.7

nan

27

63.2

31.6

nan

2013

126

48

83.3

9.8

nan

91

52.6

36.8

nan

2014

112

46

85

8.9

nan

106

58.6

34

35

2015

105

46

81.6

10.6

42.6

107

60.9

32.8

42

2016

101

47

82.1

10.3

38.8

66

58.6

29.3

51

2017

95

50

86

9.7

39.1

85

55

35

61

2018

88

48

87.2

8.6

38.5

126

68.8

17

57

2019

92

51

87.6

8.2

35.5

104

73

16

57

Only first 10 rows of 12 are shown.

scaleup_parameters

parameter

target_value

min_value

max_value

tb_treatment_coverage

90

0

100

tb_prob_tx_success_ds

0.9

0

1

tb_prob_tx_success_mdr

0.9

0

1

tb_prob_tx_success_0_4

0.9

0

1

tb_prob_tx_success_5_14

0.9

0

1

first_line_test

xpert

sputum

xpert

second_line_test

sputum

sputum

xpert

ipt_coverage_plhiv

0.9

0

1

ipt_coverage_paediatric

90

0

100