parameter values (.csv)

Download original .csv file from GitHub

parameter_name

value

param_label

prior_min

prior_max

prior_note

reference

notes

0

init_pr_depr_m_age1519_no_cc_wealth123

0.06

local

0.01

1

vague prior

1

init_rp_depr_f_not_rec_preg

1.5

local

0.01

100

vague prior

2

init_rp_depr_f_rec_preg

3

local

0.01

100

vague prior

3

init_rp_depr_age2059

1

local

0.01

100

vague prior

4

init_rp_depr_agege60

3

local

0.01

100

vague prior

5

init_rp_depr_cc

1

local

0.01

100

vague prior

6

init_rp_depr_wealth45

1

local

0.01

100

vague prior

7

init_rp_ever_depr_per_year_older_m

0.004

local

0.01

100

vague prior

8

init_rp_ever_depr_per_year_older_f

0.006

local

0.01

100

vague prior

9

init_pr_antidepr_curr_depr

0.11

local

0

1

vague prior

10

init_rp_antidepr_ever_depr_not_curr

0.5

local

0.01

100

vague prior

11

init_pr_ever_diagnosed_depression

0.2

local

0

1

vague prior

12

init_pr_ever_talking_therapy_if_diagnosed

1

local

0

1

vague prior

We assume that talking therapy happens as part of diagnosis

13

init_pr_ever_self_harmed_if_ever_depr

0.004

local

0

1

vague prior

consistent with rate of incident self harm

14

base_3m_prob_depr

0.0021

undetermined

0

1

calibration

Rate is derived indirectly based on prevalence of depression that model produces as an output (Abas et al, 1997; Marwick et al, 2010; Udedi et al, 2014; This is much higher than incidence in Todd et al 1999 (approx 0.16 in 2 months) but that is inconsistent with prevalence unless extremely short duration. )

15

rr_depr_wealth45

3

local

0.01

100

vague prior

Abas et al, 1997; Todd et al 1999; Chibanda et al, 2012;

Abas et al, 1997; Todd et al 1999; Chibanda et al, 2012;

16

rr_depr_cc

1.25

local

0.01

100

vague prior

HIV: Cohen et al Rwanda 2009; Brandt 2009; hypertension: no association in SA Grimsrud et al 2009. Likely the association is with chronic symptoms rather than diagnosis of a chronic condition.

17

rr_depr_pregnancy

3

local

0.01

100

vague prior

could not identify any estimates for African countries; although clear that pregnancy prevalence is relatively high in pregnancy and post-partum (it is clear the relative rate is > 1). Suggest use value of 3 until we have more data.

18

rr_depr_female

1.5

local

0.01

100

vague prior

Kohler et al 2017

Kohler et al 2017

19

rr_depr_prev_epis

50

local

0.01

100

vague prior

No data identified from Malawi or other close countries, but likely to be a large person-specific effect. Consider data on proportion of people with depression ever.

20

rr_depr_on_antidepr

30

local

0.01

100

vague prior

21

rr_depr_age1519

1

local

0.01

100

vague prior

Kim et al 2015

Kim et al 2015

22

rr_depr_agege60

3

local

0.01

100

vague prior

Kohler et al 2017

Kohler et al 2017

23

rr_depr_hiv

1.99

local

0.01

100

vague prior

Ciesla & Roberts 2001

Ciesla & Roberts 2001

24

depr_resolution_rates

[0.2, 0.3, 0.5, 0.7, 0.95]

local

[0, 0, 0, 0, 0]

[1, 1, 1, 1, 1]

vague prior

Abas et al, 1997; Dow et al 2014

Abas et al, 1997; Dow et al 2014

25

rr_resol_depr_cc

0.5

local

0.01

100

vague prior

26

rr_resol_depr_on_antidepr

1.5

universal

0.01

100

vague prior

Hengartner 2017; Cipriani et al 2018; Furukawa et al 2016;Faria et 2017; Kirsch 2014;

Hengartner 2017; Cipriani et al 2018; Furukawa et al 2016;Faria et 2017; Kirsch 2014;

27

rr_resol_depr_current_talk_ther

1.1

local

0.01

100

vague prior

28

prob_3m_stop_antidepr

0.7

local

0

1

vague prior

29

prob_3m_default_antidepr

0.2

local

0

1

vague prior

30

prob_3m_suicide_depr_m

0.0005

local

0

1

vague prior

Chasimpha et al 2015 to be infered based on overall suicide rate and prevalence of depression (assume depression a pre-requisite for suicide) Suicide rate in adults in Karonga study 26.1 per 100,000 person years in adult men (age ge 15) and 8.0 per 100,000 person years in adult women. Chasimpha et al BMC Public Health 2015

Chasimpha et al 2015 to be infered based on overall suicide rate and prevalence of depression (assume depression a pre-requisite for suicide) Suicide rate in adults in Karonga study 26.1 per 100,000 person years in adult men (age ge 15) and 8.0 per 100,000 person years in adult women. Chasimpha et al BMC Public Health 2015

31

rr_suicide_depr_f

0.333

local

0.01

100

vague prior

Chasimpha et al 2015

Chasimpha et al 2015

32

prob_3m_selfharm_depr

0.0005

local

0

1

vague prior

33

sensitivity_of_assessment_of_depression

0.75

universal

0

1

vague prior

34

pr_assessed_for_depression_in_generic_appt_level1

0.01

local

0

1

vague prior

No available reference found, but co-calibrated with pr_assessed_for_depression_for_perinatal_female for a better Model/Data ratio on mental health service usage.

35

anti_depressant_medication_item_code

267

local

1

1000

vague prior

First line treatment (Amitriptyline 25mg_100_CMST)

36

pr_assessed_for_depression_for_perinatal_female

0.01

local

0

1

vague prior

No available reference found, but co-calibrated with pr_assessed_for_depression_in_generic_appt_level1 for a better Model/Data ratio on mental health service usage.

37

recently_pregnant_threshold_years

1

undetermined

1

5

design decision

38

max_talking_therapy_sessions

5

local

1

20

vague prior

39

talking_therapy_interval_months

6

local

1

24

vague prior

40

antidepr_refill_interval_months

1

local

1

24

vague prior

41

antidepr_refill_window_days

7

local

1

30

vague prior

42

selfharm_suicide_event_max_days

90

undetermined

1

365

design decision

43

depression_polling_frequency_months

3

undetermined

1

12

design decision

44

age_threshold_adult_care

5

local

0

20

vague prior

45

age_threshold_depression

15

local

5

20

vague prior