Depression (.xlsx)

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parameter_values

	parameter_name	value	Unnamed: 2	Justification	Unnamed: 4	Unnamed: 5	Unnamed: 6	Unnamed: 7
0	init_pr_depr_m_age1519_no_cc_wealth123	0.06		None
1	init_rp_depr_f_not_rec_preg	1.5		None
2	init_rp_depr_f_rec_preg	3		None
3	init_rp_depr_age2059	1		None
4	init_rp_depr_agege60	3		None
5	init_rp_depr_cc	1		None
6	init_rp_depr_wealth45	1		None
7	init_rp_ever_depr_per_year_older_m	0.004		None
8	init_rp_ever_depr_per_year_older_f	0.006		None
9	init_pr_antidepr_curr_depr	0.11		None
10	init_rp_antidepr_ever_depr_not_curr	0.5		None
11	init_pr_ever_diagnosed_depression	0.2		None
12	init_pr_ever_talking_therapy_if_diagnosed	1		We assume that talking therapy happens as part of diagnosis
13	init_pr_ever_self_harmed_if_ever_depr	0.004		consistent with rate of incident self harm
14	base_3m_prob_depr	0.0021		Rate is derived indirectly based on prevalence of depression that model produces as an output (Abas et al, 1997; Marwick et al, 2010; Udedi et al, 2014; This is much higher than incidence in Todd et al 1999 (approx 0.16 in 2 months) but that is inconsistent with prevalence unless extremely short duration. )
15	rr_depr_wealth45	3		Abas et al, 1997; Todd et al 1999; Chibanda et al, 2012;
16	rr_depr_cc	1.25		HIV: Cohen et al Rwanda 2009; Brandt 2009; hypertension: no association in SA Grimsrud et al 2009. Likely the association is with chronic symptoms rather than diagnosis of a chronic condition.
17	rr_depr_pregnancy	3		could not identify any estimates for African countries; although clear that pregnancy prevalence is relatively high in pregnancy and post-partum (it is clear the relative rate is > 1). Suggest use value of 3 until we have more data.
18	rr_depr_female	1.5		Kohler et al 2017
19	rr_depr_prev_epis	50		No data identified from Malawi or other close countries, but likely to be a large person-specific effect. Consider data on proportion of people with depression ever.
20	rr_depr_on_antidepr	30
21	rr_depr_age1519	1		Kim et al 2015;
22	rr_depr_agege60	3		Kohler et al 2017;
23	rr_depr_hiv	1.99		Ciesla & Roberts 2001;
24	depr_resolution_rates	[0.2, 0.3, 0.5, 0.7, 0.95]		Abas et al, 1997; Dow et al 2014;
25	rr_resol_depr_cc	0.5
26	rr_resol_depr_on_antidepr	1.5		Hengartner 2017; Cipriani et al 2018; Furukawa et al 2016;Faria et 2017; Kirsch 2014;
27	rr_resol_depr_current_talk_ther	1.1
28	prob_3m_stop_antidepr	0.7		None
29	prob_3m_default_antidepr	0.2		None
30	prob_3m_suicide_depr_m	0.0005		Chasimpha et al 2015 to be infered based on overall suicide rate and prevalence of depression (assume depression a pre-requisite for suicide) Suicide rate in adults in Karonga study 26.1 per 100,000 person years in adult men (age ge 15) and 8.0 per 100,000 person years in adult women. Chasimpha et al BMC Public Health 2015
31	rr_suicide_depr_f	0.333		Chasimpha et al 2015
32	prob_3m_selfharm_depr	0.0005		None
33	sensitivity_of_assessment_of_depression	0.75		None
34	pr_assessed_for_depression_in_generic_appt_level1	0.01		No available reference found, but co-calibrated with pr_assessed_for_depression_for_perinatal_female for a better Model/Data ratio on mental health service usage.
35	anti_depressant_medication_item_code	267		First line treatment (Amitriptyline 25mg_100_CMST)
36	pr_assessed_for_depression_for_perinatal_female	0.01		No available reference found, but co-calibrated with pr_assessed_for_depression_in_generic_appt_level1 for a better Model/Data ratio on mental health service usage.